Article Figures & Data
Figures
- Fig 1.
The distribution of collateral scores in different clot locations. Collateral scores 3 and 4 are pooled into same group.
- Fig 2.
Collateral score and the site of the occlusion predict the clinical outcome. A proximal clot (ICA or M1P) is more strongly associated with unfavorable outcome than poor collateral status (CS 0–1).
Tables
- Table 1:
Demographic and baseline characteristics of all patients and by good collateral status, the locus of the thrombus, and 3-month outcome
Characteristic All Patients (n = 105) Collateral Score 0–1 (n = 47) Collateral Score 2–4 (n = 58) P1 mRS ≤2 at Day 90 (n = 54) mRS 3–6 at Day 90 (n = 50) P2 Proximal Thrombus (ICA+M1P, n = 38) Distal Thrombus (M1D+M2+M3, n = 67) P3 Age (yr) (mean) (SD) 68.8 (13.5) 70.1 (14.4) 67.8 (12.7) .38 66.4 (13.1) 71.3 (13.6) .06 66.0 (15.1) 70.4 (12.3) .11 Male (%) 60 (57) 29 (62) 31 (53) .40 32 (59) 28 (56) .74 27 (71) 33 (49) .03 NIHSS score before treatment (median) (IQR) 13 (10) 15 (7) 11 (12) .02 9 (10) 17 (7) <.001 18 (7) 11 (10) <.001 NIHSS score 24 hours after thrombolysis (median) (IQR) 6 (14) 14 (14) 3 (7) <.001 2 (4) 16 (11) <.001 15 (10) 3 (7) <.001 ASPECTS at admission CT (median) (IQR) 10 (2) 8 (3) 10 (0) <.001 10 (1) 9 (2) .20 9 (3) 10 (2) .07 ASPECTS at 24 hours after CT (median) (IQR) 7 (5) 5 (4) 8.5 (3) <.001 9 (3) 5 (4) <.001 4 (5) 8 (4) <.001 Collateral score (median) (IQR) 2 (3) 0 (1) 3 (1) <.001 3 (1) 1 (2) <.001 1 (3) 2 (2) .01 Onset-to-treatment time (min) (mean) (SD) 132 (27) 124 (26) 138 (27) .008 133 (26) 129 (29) .46 131 (31) 132 (25) .85 Hypertension (No.) (%) 69 (65.7) 31 (66) 38 (66) .96 36 (66.7) 33 (66.0) .94 22 (57.9) 47 (70.1) .20 Diabetes (No.) (%) 17 (16.2) 9 (19) 8 (14) .46 6 (11.1) 11 (22.0) .13 8 (21.1) 9 (13.4) .31 Atrial fibrillation (No.) (%) 41 (39.0) 19 (40) 22 (38) .79 23 (42.6) 18 (36.0) .49 12 (31.6) 29 (43.3) .24 Coronary artery disease (No.) (%) 35 (33.3) 19 (40) 16 (28) .17 12 (22.2) 23 (46.0) .01 16 (42.1) 19 (28.4) .15 Note:—P1 indicates a P value between poor and good collateral status; P2, P value between mRS ≤ 2 and mRS > 2 groups; P3, P value between the proximal and distal thrombus groups; IQR, interquartile range; min, minutes.
mRS ≤2 at 2 Months Odds Ratio 95% CI P Value Clot location – – .003 ICA ref ref – M1 proximal 10.1 0.74–140 .08 M1 distal 33.8 2.9–428 .007 M2 and M3 115.8 7.7–1737 .001 Onset-to-treatment time 0.99 0.97–1.02 .44 Sex 0.34 0.09–1.3 .11 Age 0.95 0.90–0.99 .02 Admission NIHSS score 0.81 0.71–0.92 .001 Favorable CS (2–4) 9.3 2.4–35.8 .001 Note:—ref indicates reference location; –, not applicable.
↵a Odds ratios are per minute for onset-to-treatment time, per year for age, and per 1 point for NIHSS.
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