Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home

User menu

  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

ASHNR American Society of Functional Neuroradiology ASHNR American Society of Pediatric Neuroradiology ASSR
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds

AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Research ArticleNeurointervention

Cavernous Carotid Aneurysms in the Era of Flow Diversion: A Need to Revisit Treatment Paradigms

O. Tanweer, E. Raz, A. Brunswick, D. Zumofen, M. Shapiro, H.A. Riina, M. Fouladvand, T. Becske and P.K. Nelson
American Journal of Neuroradiology December 2014, 35 (12) 2334-2340; DOI: https://doi.org/10.3174/ajnr.A4081
O. Tanweer
aFrom the Departments of Neurosurgery (O.T., A.B., D.Z., P.K.N.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
E. Raz
bRadiology (E.R., D.Z., M.S., H.A.R., T.B., P.K.N.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
A. Brunswick
aFrom the Departments of Neurosurgery (O.T., A.B., D.Z., P.K.N.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
D. Zumofen
aFrom the Departments of Neurosurgery (O.T., A.B., D.Z., P.K.N.)
bRadiology (E.R., D.Z., M.S., H.A.R., T.B., P.K.N.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
M. Shapiro
bRadiology (E.R., D.Z., M.S., H.A.R., T.B., P.K.N.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
H.A. Riina
bRadiology (E.R., D.Z., M.S., H.A.R., T.B., P.K.N.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
M. Fouladvand
cNeurology (M.F., T.B., P.K.N.), New York University School of Medicine, New York, New York.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
T. Becske
bRadiology (E.R., D.Z., M.S., H.A.R., T.B., P.K.N.)
cNeurology (M.F., T.B., P.K.N.), New York University School of Medicine, New York, New York.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
P.K. Nelson
aFrom the Departments of Neurosurgery (O.T., A.B., D.Z., P.K.N.)
bRadiology (E.R., D.Z., M.S., H.A.R., T.B., P.K.N.)
cNeurology (M.F., T.B., P.K.N.), New York University School of Medicine, New York, New York.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF
Loading

Article Figures & Data

Figures

  • Tables
  • Fig 1.
    • Download figure
    • Open in new tab
    • Download powerpoint
    Fig 1.

    A 65-year-old woman who presented with progressive left-sided ophthalmoparesis due to third and fourth cranial nerve palsy. Digital subtraction angiography in frontal (A) and lateral (B) views demonstrates a large (19-mm-diameter) aneurysm arising from the cavernous segment of the left internal carotid artery. The patient was treated by endoluminal reconstruction of the LICA with 3 overlapping PEDs (frontal, C, and lateral, D). One-year follow-up digital subtraction angiography in frontal (E) and lateral (F) views and 5-year follow-up digital subtraction angiography in frontal (G) and lateral (H) views confirm stable angiographic cure. Regression of symptoms was correlated with the resolution of aneurysm mass effect as illustrated by comparison of the pretreatment gadolinium-enhanced axial T1-weighted MR image (I, white arrow) with the 5-year follow-up axial T2-weighted MR image (J).

  • Fig 2.
    • Download figure
    • Open in new tab
    • Download powerpoint
    Fig 2.

    Radiographic outcomes at 6, 12, and 36 months.

Tables

  • Figures
    • View popup
    Table 1:

    Generally accepted indications to treat CCAs

    Indications
    Symptomatic CCAs
        Symptomatic mass effect (ophthalmoplegia or intractable retro-orbital pain)
        Symptomatic with acute thrombotic changes
    Symptomatic or asymptomatic CCAs
        Ruptured aneurysms
        Bony erosion
        Radiographic evidence of projection into subarachnoid space
        Underlying coagulopathy
        Large aneurysms (>10 mm)
        Evidence of growth of aneurysms
    • View popup
    Table 2:

    Demographics, patient presentation, and aneurysm characteristics

    No. or Mean
    Age (yr)57 ± 14.2
    Female83.7% (36)
    Presenting symptom
        Visual65.1% (28)
        Headaches16.3% (7)
        Thromboembolic event4.7% (2)
        Memory2.3% (1)
        Facial pain/numbness2.3% (1)
    Aneurysm maximum diameter (mm)24.3 ± 9.7
        Small, <10 mm0
        Large, 10–25 mm23
        Giant, ≥25 mm20
    Aneurysm neck (mm)13.6 ± 11.6
    Dome-to-neck ratio2.2 ± .9
    • View popup
    Table 3:

    Systematic review of the literature for flow diversion of CCAs

    StudyTotal Aneurysms in StudySilk or PEDCCAs (No.)Major Morbidity (No.)Mortality (No.)
    Berge et al2977Silk2930
    Becske et al7,a108PED2810
    Chan et al3013PED500
    Chitale et al3142PED1620
    Cinar et al3255PED500
    Fischer et al33,b101PED1510
    Lubicz et al3434Silk510
    Lylyk et al563PED1100
    McAuliffe et al35,c57PED1100
    Nelson et al631PED500
    O'Kelly et al894PED2800
    Piano et al36104Silk1610
    PED
    Saatci et al37251PED2810
    Velioglu et al38,d87Silk1901
    Yu et al27,e178PED3211
    Current study43PED4310
    Total133829612 (4.1%)2 (0.7%)
    PED only2277 (3.1%)1 (0.44%)
    0.68Silk only534 (7.5%)1 (1.9%)
    • ↵a T. Becske, MD, personal oral communication, April 2013.

    • ↵b H. Henkes, MD, personal e-mail communication, April 2013.

    • ↵c W. McAuliffe, MD, personal e-mail communication, April 2013.

    • ↵d N. Kocer, MD, personal e-mail communication, April 2013.

    • ↵e S.C. Yu, MD, personal e-mail communication, April 2013.

PreviousNext
Back to top

In this issue

American Journal of Neuroradiology: 35 (12)
American Journal of Neuroradiology
Vol. 35, Issue 12
1 Dec 2014
  • Table of Contents
  • Index by author
  • Complete Issue (PDF)
Advertisement
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Cavernous Carotid Aneurysms in the Era of Flow Diversion: A Need to Revisit Treatment Paradigms
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Cite this article
O. Tanweer, E. Raz, A. Brunswick, D. Zumofen, M. Shapiro, H.A. Riina, M. Fouladvand, T. Becske, P.K. Nelson
Cavernous Carotid Aneurysms in the Era of Flow Diversion: A Need to Revisit Treatment Paradigms
American Journal of Neuroradiology Dec 2014, 35 (12) 2334-2340; DOI: 10.3174/ajnr.A4081

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
0 Responses
Respond to this article
Share
Bookmark this article
Cavernous Carotid Aneurysms in the Era of Flow Diversion: A Need to Revisit Treatment Paradigms
O. Tanweer, E. Raz, A. Brunswick, D. Zumofen, M. Shapiro, H.A. Riina, M. Fouladvand, T. Becske, P.K. Nelson
American Journal of Neuroradiology Dec 2014, 35 (12) 2334-2340; DOI: 10.3174/ajnr.A4081
del.icio.us logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Purchase

Jump to section

  • Article
    • Abstract
    • ABBREVIATIONS:
    • Materials and Methods
    • Results
    • Discussion
    • Conclusions
    • Footnotes
    • References
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • Reconstruction of the sphenoid sinus erosion or dehiscence after treatment of unruptured intracavernous aneurysms with flow diverter stents
  • Long-term outcomes of flow diversion for unruptured intracranial aneurysms: a systematic review and meta-analysis
  • Flow diversion for compressive unruptured internal carotid artery aneurysms with neuro-ophthalmological symptoms: a systematic review and meta-analysis
  • Onset-to-treatment time and aneurysmal regression predict improvement of cranial neuropathy after flow diversion treatment in patients with symptomatic internal carotid artery aneurysms
  • Flow diversion for compressive unruptured internal carotid artery aneurysms with neuro-ophthalmological symptoms: a systematic review and meta-analysis
  • Onset-to-treatment time and aneurysmal regression predict improvement of cranial neuropathy after flow diversion treatment in patients with symptomatic internal carotid artery aneurysms
  • Flow diversion for internal carotid artery aneurysms with compressive neuro-ophthalmologic symptoms: clinical and anatomical results in an international multicenter study
  • Use of flow diverter stent for treatment of a cervical carotid artery dissection and pseudoaneurysm causing Horners syndrome
  • Flow Diversion in Ruptured Intracranial Aneurysms: A Meta-Analysis
  • Carotid cavernous fistula after Pipeline placement: a single-center experience and review of the literature
  • Treatment of direct carotid-cavernous fistulas with a double lumen balloon
  • Therapeutic Internal Carotid Artery Occlusion for Large and Giant Aneurysms: A Single Center Cohort of 146 Patients
  • Crossref
  • Google Scholar

This article has not yet been cited by articles in journals that are participating in Crossref Cited-by Linking.

More in this TOC Section

  • A Retrospective Study in Tentorial DAVFs
  • Proximal Protection Devices for Carotid Stenting
  • Rescue Reentry in Carotid Near-Occlusion
Show more NEUROINTERVENTION

Similar Articles

Advertisement

Indexed Content

  • Current Issue
  • Accepted Manuscripts
  • Article Preview
  • Past Issues
  • Editorials
  • Editor's Choice
  • Fellows' Journal Club
  • Letters to the Editor
  • Video Articles

Cases

  • Case Collection
  • Archive - Case of the Week
  • Archive - Case of the Month
  • Archive - Classic Case

More from AJNR

  • Trainee Corner
  • Imaging Protocols
  • MRI Safety Corner
  • Book Reviews

Multimedia

  • AJNR Podcasts
  • AJNR Scantastics

Resources

  • Turnaround Time
  • Submit a Manuscript
  • Submit a Video Article
  • Submit an eLetter to the Editor/Response
  • Manuscript Submission Guidelines
  • Statistical Tips
  • Fast Publishing of Accepted Manuscripts
  • Graphical Abstract Preparation
  • Imaging Protocol Submission
  • Evidence-Based Medicine Level Guide
  • Publishing Checklists
  • Author Policies
  • Become a Reviewer/Academy of Reviewers
  • News and Updates

About Us

  • About AJNR
  • Editorial Board
  • Editorial Board Alumni
  • Alerts
  • Permissions
  • Not an AJNR Subscriber? Join Now
  • Advertise with Us
  • Librarian Resources
  • Feedback
  • Terms and Conditions
  • AJNR Editorial Board Alumni

American Society of Neuroradiology

  • Not an ASNR Member? Join Now

© 2025 by the American Society of Neuroradiology All rights, including for text and data mining, AI training, and similar technologies, are reserved.
Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire