Article Figures & Data
Figures
- Fig 1.
A–C, Glioblastoma multiforme involving the paraventricular region of the right frontal lobe seen on axial T2-weighted, T1-weighted postgadolinium, and DSC CBV. D–F, IVIM parametric maps f, D*, and fD* (scale bars: f = unitless; D*, fD* = mm2s−1). G, Logarithmic plot of signal-intensity decay as a function of b of the region of interest of maximal perfusion fraction, with the corresponding biexponential fit.
- Fig 2.
A–C, Oligoastrocytoma, grade 2, centered on the pre-central gyrus of the right frontal lobe, seen on axial T2-weighted, T1-weighted postgadolinium, and DSC CBV. D–F, IVIM parametric maps f, D*, and fD* (scale bars: f = unitless; D*, fD* = mm2s−1). G, Logarithmic plot of signal-intensity decay as a function of b of the region of interest of the maximal perfusion fraction, with the corresponding biexponential fit.
- Fig 3.
Box-and-whisker plot (median, 25th and 75th percentiles, minimum, maximum, and outliers) of f, D*, fD*, and D, as measured in ROIs of the maximum perfusion fraction. Dark gray indicates high-grade tumors; medium gray, low-grade tumors; light gray, contralateral control region of both high- and low- grade. P values are indicated when <.05.
- Fig 4.
Scatterplots comparing relative DSC CBV (y-axis) with absolute IVIM f (x-axis). Pearson r correlation coefficient is given.
- Fig 5.
Normalized histograms of the perfusion fraction comprising the voxels of all whole tumor volumes for the high-grade (A) and low-grade (B) groups and for the control group (C). The total number of voxels included is indicated by n. An increase in the normalized number of highly perfused voxels can be observed in the high-grade tumor group in comparison with the low-grade and control groups.
Tables
Grade Age (yr) Sex Localization Sample Obtained Pathologic Diagnosis WHO Grade High 1 77 Male Left parietal lobe Surgical resection Glioblastoma multiforme IV 2 67 Male Right parietal lobe Surgical resection Glioblastoma multiforme IV 3 84 Female Left parietal lobe Stereotaxic biopsy Glioblastoma multiforme IV 4 61 Female Right frontal lobe Surgical resection Glioblastoma multiforme IV 5 60 Male Right frontal lobe Surgical resection Glioblastoma multiforme IV 6 68 Male Right insula Surgical resection Glioblastoma multiforme IV 7 73 Male Right frontotemporal lobes Surgical resection Anaplastic oligoastrocytoma III 8 36 Male Left insula Stereotaxic biopsy Diffuse glioma III 9 50 Male Left temporal lobe Stereotaxic biopsy Glioblastoma multiforme IV 10 43 Male Left temporal lobe Surgical resection Glioblastoma multiforme IV 11 73 Male Left temporal lobe Surgical resection Glioblastoma multiforme IV 12 53 Male Left parietal lobe Surgical resection Glioblastoma multiforme IV 13 60 Female Left operculum Stereotaxic biopsy Glioblastoma multiforme IV 14 24 Male Left cingulum Stereotaxic biopsy Anaplastic oligoastrocytoma III 15 61 Male Left temporal lobe Surgical resection Glioblastoma multiforme IV 16 63 Female Right frontal lobe Surgical resection Glioblastoma multiforme IV Low 1 38 Male Right frontal lobe Surgical resection Oligoastrocytoma II 2 58 Male Right frontal lobe Surgical resection Neuroglial tumor II 3 54 Male Left temporo-occipital lobes Stereotaxic biopsy Diffuse astrocytoma II 4 38 Male Left frontal lobe Stereotaxic biopsy Oligodendroglioma II 5 2 Male Centered on 3rd ventricle Stereotaxic biopsy Pilomyxoid astrocytoma II Note:—WHO indicates World Health Organization.
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