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Research ArticleHead & Neck

Actinomycosis in the Mandible: CT and MR Findings

Y. Sasaki, T. Kaneda, J.W. Uyeda, H. Okada, K. Sekiya, M. Suemitsu and O. Sakai
American Journal of Neuroradiology February 2014, 35 (2) 390-394; DOI: https://doi.org/10.3174/ajnr.A3673
Y. Sasaki
aFrom the Departments of Radiology (Y.S., T.K., K.S.)
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T. Kaneda
aFrom the Departments of Radiology (Y.S., T.K., K.S.)
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J.W. Uyeda
dDepartment of Radiology (J.W.U., O.S.) Boston Medical Center, Boston University School of Medicine, Boston, Massachusetts.
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H. Okada
bHistology (H.O.)
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K. Sekiya
aFrom the Departments of Radiology (Y.S., T.K., K.S.)
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M. Suemitsu
cPathology (M.S.), Nihon University School of Dentistry at Matsudo, Chiba, Japan
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O. Sakai
dDepartment of Radiology (J.W.U., O.S.) Boston Medical Center, Boston University School of Medicine, Boston, Massachusetts.
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  • Fig 1.
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    Fig 1.

    A 68-year-old woman with discharge of pus on the right side of the face. A, Panoramic radiograph reveals a large osteolytic region (arrows), with a floating tooth (arrowhead), in the right mandibular body crossing the midline. Axial CT in bone (B) and soft tissue (C) windows reveals an ill-defined osteolytic lesion in the right mandibular body crossing the midline (arrows). Note extensive demineralization of the buccal and lingual cortices and extensive soft tissue infiltrative change extending to the skin (arrowheads). D and E, Coronal CT in soft tissue window shows bone destruction and fistula from the mandible to the skin (arrows). F, Axial T1-weighted MR image shows heterogeneous, low signal intensity in the lesion involving the mandible and surrounding soft tissues (arrow). G, Contrast-enhanced axial T1-weighted MR image shows heterogeneous mass with moderate contrast enhancement in the lesion involving the mandible and surrounding soft tissues (arrow). H, Coronal T2-weighted MR image shows a fistula (arrow). I and J, Axial STIR MR images shows multiple mildly reactive nodes with increased signal intensity in levels IA and IB (arrows). K, Photomicrograph of a specimen shows actinomycotic granules (arrowheads) and presence of sequestra (arrows) (hematoxylin-eosin stain, original magnification × 200).

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    Fig 2.

    A 40-year-old man with discharge of pus on the right side of the face. A, Axial CT in soft tissue window reveals extensive soft tissue (outer layer fat around mandible) infiltrative change extending to the skin (arrow). B, Contrast-enhanced axial CT scan in soft tissue window reveals a heterogeneous, moderately enhancing mass in the lesion and extensive soft tissue (outer layer fat around mandible) infiltrative change extending to the skin (arrow). Axial T1-weighted (C) and contrast-enhanced axial T1-weighted (D) MR imaging reveals heterogeneous, low signal intensity in the lesion involving the mandible and surrounding soft tissues (arrow). Note this lesion shows diffuse and moderate contrast enhancement of the soft tissue and marrow space.

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    Fig 3.

    A 28-year-old man with swelling of the right mandibular region. A, Axial CT in bone window shows a heterogeneous osteolytic lesion with periosteal reaction in the posterior body to ramus of the right mandible (arrows). B, Axial CT in soft tissue window shows extensive soft tissue infiltrative change extending to the skin (arrow), masseter muscle (arrowhead), and parotid gland (thin arrow).

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    Fig 4.

    A 66-year-old woman with swelling of left mandibular region. A, Axial CT in soft tissue window demonstrates foci of air adjacent to the left mandible (arrow) and swelling of masseter and medial pterygoid muscle (arrowheads). B, Axial STIR MR image shows extensive inflammation in the left masseter muscle, medial pterygoid muscles, parotid gland (arrowheads), and mandibular bone marrow (arrow).

Tables

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    Table 1:

    CT imaging features of MA

    Patient No/Age (y)/SexCT Imaging Findings
    Contrast EnhancementMarginDensityIntralesional GasFistulaOsteolysisPeriosteal ReactionSequestraLymphadenopathy
    1/40/MMod. heterog.IrregularLow–intermed.−++++−
    2/34/MNot doneIrregularLow–intermed.+++−−−
    3/66/FNot doneIrregularLow–intermed.+−+++−
    4/28/MNot doneIrregularLow–intermed.−++++−
    5/78/FNot doneIrregularLow–intermed.+++++−
    6/68/FNot doneIrregularLow–intermed.+−+−−−
    • Note:—F indicates female; M, male; Low–intermed., low to intermediate; Mod. heterog., moderate heterogeneous.

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    Table 2:

    MR imaging features of actinomycosis in the mandible

    Patient NoMRI Findings
    Gadolinium EnhancementCellulitis Adjacent to the Facial SkinInflammation of Masseter MuscleInflammation of Pterygoid MuscleLymph Adenopathy
    1Moderate heterogeneous+−−
    2Not done++−−
    3Not done+++−
    4Not done+++−
    5Not done+++−
    6Moderate heterogeneous+++−
    • Note:—+ indicates findings present; −, findings absent.

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American Journal of Neuroradiology: 35 (2)
American Journal of Neuroradiology
Vol. 35, Issue 2
1 Feb 2014
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Cite this article
Y. Sasaki, T. Kaneda, J.W. Uyeda, H. Okada, K. Sekiya, M. Suemitsu, O. Sakai
Actinomycosis in the Mandible: CT and MR Findings
American Journal of Neuroradiology Feb 2014, 35 (2) 390-394; DOI: 10.3174/ajnr.A3673

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Actinomycosis in the Mandible: CT and MR Findings
Y. Sasaki, T. Kaneda, J.W. Uyeda, H. Okada, K. Sekiya, M. Suemitsu, O. Sakai
American Journal of Neuroradiology Feb 2014, 35 (2) 390-394; DOI: 10.3174/ajnr.A3673
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