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AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Research ArticlePediatric Neuroimaging
Open Access

MR Imaging Evaluation of Inferior Olivary Nuclei: Comparison of Postoperative Subjects with and without Posterior Fossa Syndrome

Z. Patay, J. Enterkin, J.H. Harreld, Y. Yuan, U. Löbel, Z. Rumboldt, R. Khan and F. Boop
American Journal of Neuroradiology April 2014, 35 (4) 797-802; DOI: https://doi.org/10.3174/ajnr.A3762
Z. Patay
aFrom the Departments of Radiological Sciences (Z.P., J.H.H., U.L.)
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J. Enterkin
eDepartment of Radiology (J.E., Z.R.), Medical University of South Carolina, Charleston, South Carolina.
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J.H. Harreld
aFrom the Departments of Radiological Sciences (Z.P., J.H.H., U.L.)
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Y. Yuan
bBiostatistics (Y.Y.)
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U. Löbel
aFrom the Departments of Radiological Sciences (Z.P., J.H.H., U.L.)
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Z. Rumboldt
eDepartment of Radiology (J.E., Z.R.), Medical University of South Carolina, Charleston, South Carolina.
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R. Khan
cPediatrics (R.K.)
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F. Boop
dSurgery (F.B.), St. Jude Children's Research Hospital, Memphis, Tennessee
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    Fig 1.

    The Guillain-Mollaret triangle and dentatorubrothalamocortical projections.

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    Fig 2.

    Transverse proton attenuation–weighted images illustrating the MR imaging appearance of normal IONs (A, white arrows) and unilateral (B, black arrow) and bilateral (C, black arrows) HOD in patients approximately 4 months after surgery for midline posterior fossa tumors. Note that with this imaging technique, normal IONs (white arrows) are barely recognizable, but in abnormal conditions, their conspicuity is markedly increased, allowing confident identification of HOD in most cases.

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    Fig 3.

    Transverse proton attenuation–weighted images showing chronologic changes (increasing conspicuity) within the bilateral inferior olivary nuclei (white arrowheads) in a patient with PFS during the first year after surgery. A, Preoperative study. B, At 1-month follow-up. C, At 6-month follow-up. D, At 10-month follow-up.

Tables

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  • Clinical features of patients with and without posterior fossa syndrome

    VariablePFS (n = 12)Non-PFS (n = 12)
    Mutism >24 hours120
    Immediate postoperative
        Mild-to-moderate dysmetria72
        Severe dysmetria50
        Mild-to-moderate ataxia07
        Severe ataxia122
    At last follow-upa
        Mild-to-moderate dysmetria20
        Severe dysmetria10
        Mild-to-moderate ataxia75
        Severe ataxia51
    • Note:—Dysmetria: incoordination of limbs with either some (i.e., mild to moderate) or complete (i.e., severe) impairment of function. Ataxia: impaired ability to sit and walk with independent mobility retained (mild to moderate) or with mobility assistance required (severe).

    • ↵a Time to last follow-up evaluation: 3–99 months.

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American Journal of Neuroradiology: 35 (4)
American Journal of Neuroradiology
Vol. 35, Issue 4
1 Apr 2014
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Cite this article
Z. Patay, J. Enterkin, J.H. Harreld, Y. Yuan, U. Löbel, Z. Rumboldt, R. Khan, F. Boop
MR Imaging Evaluation of Inferior Olivary Nuclei: Comparison of Postoperative Subjects with and without Posterior Fossa Syndrome
American Journal of Neuroradiology Apr 2014, 35 (4) 797-802; DOI: 10.3174/ajnr.A3762

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MR Imaging Evaluation of Inferior Olivary Nuclei: Comparison of Postoperative Subjects with and without Posterior Fossa Syndrome
Z. Patay, J. Enterkin, J.H. Harreld, Y. Yuan, U. Löbel, Z. Rumboldt, R. Khan, F. Boop
American Journal of Neuroradiology Apr 2014, 35 (4) 797-802; DOI: 10.3174/ajnr.A3762
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