Article Figures & Data
Tables
- Table 1:
Reason for ineligibility for randomization among the patients screened for the trial
Reason for Ineligibility No. % Improvement of neurologic status before randomization 8 23 Expiry of time window for randomization 5 13 Emergency clot evacuation 5 13 Hemodynamic instability 5 13 Beyond age range 4 11 Pure intraventricular hemorrhage 3 8 Signs of coning 3 8 Lack of equipoise 3 8 No aneurysm on CT angiogram (AVM found) 1 3 Treatment-Unrelated Adverse Event No. Aneurysm rebleeding 1 Hydrocephalus (early) 5 Hydrocephalus (late) 1 Intracerebral hematoma 2 Intraventricular hemorrhage 2 Diffuse cerebral edema 1 Early Treatment Arm Treatment after Recovery Arm No. of patients 5 3 WFNS score on admission WFNS IV-II WFNS IV-I WFNS V-III WFNS V-II Good outcome 1 (MRS 1) 1 (MRS 0) Poor outcome 4 (all MRS 6) 2 (all MRS 6) - Table 4:
Summary of studies of patients with poor-grade subarachnoid hemorrhage treated with early endovascular coiling
Study (yr) No. of Patients Methodology Good Outcome (%) Mortality Rate (%) Bracard et al5 (2002) 80 Included HH grades 4 and 5, good outcome GOS 1 or 2, up to 1 year follow-up 52.5 (GOS 1–2) 8.75 GOS 3 37.5 van Loon et al6 (2002) 11 WFNS grade V, outcome measure GOS, mean follow-up 12 months 36 18 Weir et al7 (2003) 27 HH grades 4 and 5, outcome assessed by mRS, mean follow-up 23 months 30 59 Jain et al8 (2004) 13 Older than 70 yr, poor HH grades 4 and 5, outcome measure GOS 15 47 Bergui and Bradac9 (2004) 45 48 44 Suzuki et al10 (2006) 111 HH grades 4/5, outcome by mRS, follow-up ≤24 mo 35.1 32.4 Pereiera et al11 (2007) 51 Outcome by GOS at 12 mo, GOS 1–3 considered good; 4–5, poor 57 35 Taylor et al12 (2011) 47 WFNS grades IV/V, 6-month GOS for outcome 53 27 Note:—GOS indicates Glasgow Outcome Scale; HH, Hunt and Hess.
