Article Figures & Data
Figures
- Fig 1.
CT-guided percutaneous puncture inoculation of a VX2 tumor mass. A, Incorrect positioning of puncture needle and the adjustment of needle position and direction. B, Correct positioning of puncture needle, just at the junction of the vertebral body and left vertebral pedicle. C, Puncture needle breaking the vertebral cortical bone and reconfirming that the needle positioning is not deep enough. D, Slow advancement of the puncture needle to the middle of vertebral body.
- Fig 2.
CT scan reconstruction after successful puncture: coronal section (A), sagittal section (B), and axial section (C). The rabbit vertebra is narrow and long, with the central part being thin and small (arrowhead). The cross-section of the vertebral head is relatively thicker, and the puncture needle tip (arrow) is positioned at the relatively thicker side of vertebra head after successful puncture.
- Fig 3.
CT of a successful model of a spinal tumor. A and B, Irregular bone destruction inside the lumbar vertebrae and cortical bone destruction at the vertebra posterior border. C and D, Another experimental animal with vertebral bone destruction. The vertebral cortical bone broke at the vertebra border, with a small amount of high-attenuation osteogenesis inside.
- Fig 4.
MR images of the vertebra of a paralyzed rabbit with abnormal signal (arrow) from the L4 vertebra. A, Low signal on T1WI. B, High signal on T2WI. C, Enhanced scan shows significantly enhanced lesions and spinal cord compression.
- Fig 5.
PET-CT images of a spinal tumor in a successful rabbit model with increased uptake of radionuclide at L5 vertebra (arrow). The left column shows a reconstructed image at CT coronal and sagittal positions, the middle column shows PET image, and the right column shows PET-CT fused image.
- Fig 6.
CT-guided PVP treatment of a rabbit spinal tumor. A, High-attenuation metallic puncture needle (arrow) into the vertebral body during PVP. B, Satisfactory sedimentation of high-attenuation bone cement (arrowhead) in the vertebral body after PVP.
- Fig 7.
General pathology and hematoxylin-eosin staining of a successful animal model. A, Bone destruction at the posterior border of the vertebra, with the spinal cord (arrowhead) being compressed by the back side of the tumor (arrow). B, Magnification ×40. C, Hematoxylin-eosin staining. Tumor cells have a nest arrangement under the microscope, and the cells are bulky, with clear boundaries, a high level of cell atypia, an increased nuclear cytoplasm ratio, visible pathologic mitotic count, and a staggered arrangement of tumor cells and bone. Magnification ×400.
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