MRI Tractography of Corticospinal Tract and Arcuate Fasciculus in High-Grade Gliomas Performed by Constrained Spherical Deconvolution: Qualitative and Quantitative Analysis

Tractographic reconstruction of corticospinal tracts in patients with high-grade gliomas. Coronal T1-weighted MR image (A) shows the corticospinal tract (arrow) on the healthy side with overlay of the Pensfield motor homunculus (arrowheads indicate neoplasm margins) and the neoplasm volume segmentation (B) (blue volume). Coronal (C) and sagittal (D) rotated images show tractographic reconstruction of CSTs on both healthy (arrow) and neoplasm-affected sides (empty arrow) of the brain. In this patient, the lateral portion of the CST on the affected side is poorly represented due to neoplasm disruption. E, Coronal T1-weighted MR image shows CSTs, both on healthy (arrow) and neoplasm-affected sides (empty arrow) of another patient (neoplasm segmentation is depicted by red volume). In this case, on the affected side, the lateral portion of the CST passes through the neoplasm and is poorly involved. F, Coronal T1-weighted MR image shows the medial portion of CSTs on the healthy side (arrow) and the absence of their involvement in the neoplasm-affected one (empty arrow). N indicates neoplasm.