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Research ArticleINTERVENTIONAL
Open Access

Outcome Differences between Intra-Arterial Iso- and Low-Osmolality Iodinated Radiographic Contrast Media in the Interventional Management of Stroke III Trial

T.A. Tomsick, L.D. Foster, D.S. Liebeskind, M.D. Hill, J. Carrozella, M. Goyal, R. von Kummer, A.M. Demchuk, I. Dzialowski, V. Puetz, T. Jovin, H. Morales, Y.Y. Palesch, J. Broderick, P. Khatri, S.D. Yeatts and for the IMS III Investigators
American Journal of Neuroradiology November 2015, 36 (11) 2074-2081; DOI: https://doi.org/10.3174/ajnr.A4421
T.A. Tomsick
aFrom the Department of Radiology (T.A.T., J.C., H.M.), University of Cincinnati Academic Health Center, University Hospital, Cincinnati, Ohio
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L.D. Foster
bDepartment of Public Health Sciences (L.D.F., Y.Y.P., S.D.Y.), Medical University of South Carolina, Charleston, South Carolina
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D.S. Liebeskind
cUniversity of California, Los Angeles Stroke Center (D.S.L.), Los Angeles, California
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M.D. Hill
dDepartment of Radiology and Clinical Neurosciences (M.D.H., M.G.)
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  • ORCID record for M.D. Hill
J. Carrozella
aFrom the Department of Radiology (T.A.T., J.C., H.M.), University of Cincinnati Academic Health Center, University Hospital, Cincinnati, Ohio
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M. Goyal
dDepartment of Radiology and Clinical Neurosciences (M.D.H., M.G.)
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R. von Kummer
fDepartments of Neuroradiology (R.v.K.)
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A.M. Demchuk
eCalgary Stroke Program (A.M.D.), Department of Clinical Neurosciences/Medicine/Community Health Sciences, Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada
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I. Dzialowski
hDepartment of Neurology (I.D.), Elblandklinikum Meissen, Academic Teaching Hospital of Universitätsklinikum, Carl Gustav Carus Technische Universität Dresden, Meißen, Germany
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V. Puetz
gNeurology (V.P.), Dresden University Stroke Center, Universitätsklinikum Carl Gustav Carus Technischen Universität Dresden, Dresden, Germany
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T. Jovin
jThe Stroke Institute (T.J.), University of Pittsburgh Medical Center, Pittsburgh. Pennsylvania.
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H. Morales
aFrom the Department of Radiology (T.A.T., J.C., H.M.), University of Cincinnati Academic Health Center, University Hospital, Cincinnati, Ohio
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Y.Y. Palesch
bDepartment of Public Health Sciences (L.D.F., Y.Y.P., S.D.Y.), Medical University of South Carolina, Charleston, South Carolina
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J. Broderick
iDepartment of Neurology (J.B., P.K.), University of Cincinnati Academic Health Center, Cincinnati, Ohio
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P. Khatri
iDepartment of Neurology (J.B., P.K.), University of Cincinnati Academic Health Center, Cincinnati, Ohio
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S.D. Yeatts
bDepartment of Public Health Sciences (L.D.F., Y.Y.P., S.D.Y.), Medical University of South Carolina, Charleston, South Carolina
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Article Information

vol. 36 no. 11 2074-2081
DOI 
https://doi.org/10.3174/ajnr.A4421
PubMed 
26228892

Published By 
American Journal of Neuroradiology
Print ISSN 
0195-6108
Online ISSN 
1936-959X
History 
  • Received November 19, 2014
  • Accepted after revision March 3, 2015
  • Published online November 13, 2015.

Copyright & Usage 
© 2015 by American Journal of Neuroradiology Indicates open access to non-subscribers at www.ajnr.org

Author Information

  1. T.A. Tomsicka,
  2. L.D. Fosterb,
  3. D.S. Liebeskindc,
  4. M.D. Hilld,
  5. J. Carrozellaa,
  6. M. Goyald,
  7. R. von Kummerf,
  8. A.M. Demchuke,
  9. I. Dzialowskih,
  10. V. Puetzg,
  11. T. Jovinj,
  12. H. Moralesa,
  13. Y.Y. Paleschb,
  14. J. Brodericki,
  15. P. Khatrii,
  16. S.D. Yeattsb,
  17. for the IMS III Investigators
  1. aFrom the Department of Radiology (T.A.T., J.C., H.M.), University of Cincinnati Academic Health Center, University Hospital, Cincinnati, Ohio
  2. bDepartment of Public Health Sciences (L.D.F., Y.Y.P., S.D.Y.), Medical University of South Carolina, Charleston, South Carolina
  3. cUniversity of California, Los Angeles Stroke Center (D.S.L.), Los Angeles, California
  4. dDepartment of Radiology and Clinical Neurosciences (M.D.H., M.G.)
  5. eCalgary Stroke Program (A.M.D.), Department of Clinical Neurosciences/Medicine/Community Health Sciences, Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada
  6. fDepartments of Neuroradiology (R.v.K.)
  7. gNeurology (V.P.), Dresden University Stroke Center, Universitätsklinikum Carl Gustav Carus Technischen Universität Dresden, Dresden, Germany
  8. hDepartment of Neurology (I.D.), Elblandklinikum Meissen, Academic Teaching Hospital of Universitätsklinikum, Carl Gustav Carus Technische Universität Dresden, Meißen, Germany
  9. iDepartment of Neurology (J.B., P.K.), University of Cincinnati Academic Health Center, Cincinnati, Ohio
  10. jThe Stroke Institute (T.J.), University of Pittsburgh Medical Center, Pittsburgh. Pennsylvania.
  1. Please address correspondence to Thomas A. Tomsick, MD, University of Cincinnati Academic Health Center, UC Health, Department of Radiology, 234 Goodman St, Cincinnati, OH 45267-0761; e-mail: thomas.tomsick{at}uchealth.com
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  • Contrast-induced nephropathy: A dilemma between loss of neurons or nephrons in the setting of endovascular treatment of acute ischemic stroke
    Fernando Delgado Acosta, Elvira Jiménez Gómez, Isabel Bravo Rey, Roberto Valverde Moyano, Francisco de Asís Bravo-Rodriguez, Rafael Oteros Fernández
    Interventional Neuroradiology 2020 26 1
  • Variable MR and pathologic patterns of hemorrhage after iodinated contrast infusion in MCA occlusion/reperfusion model
    Humberto Morales, Aigang Lu, Yuko Kurosawa, Joseph F Clark, Thomas Tomsick
    Journal of NeuroInterventional Surgery 2017 9 12
  • Hemorrhagic Transformation Rates following Contrast Media Administration in Patients Hospitalized with Ischemic Stroke
    F.G. Moser, T.M. Todoran, M. Ryan, E. Baker, C. Gunnarsson, J.A. Kellum
    American Journal of Neuroradiology 2022 43 3
  • Iodinated Contrast Agents Reduce the Efficacy of Intravenous Recombinant Tissue-Type Plasminogen Activator in Acute Ischemic Stroke Patients: a Multicenter Cohort Study
    Zhicai Chen, Chao Xu, Wansi Zhong, Xiaoxian Gong, Haitao Hu, Xuting Zhang, Yi Chen, Qingqing Li, Zhongyu Luo, Zhuojian Chen, Min Lou
    Translational Stroke Research 2021 12 4
  • Reply:
    T.A. Tomsick, D.S. Liebeskind, M.D. Hill, R. von Kummer, M. Goyal, J.P. Broderick
    American Journal of Neuroradiology 2017 38 6
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Cite this article
T.A. Tomsick, L.D. Foster, D.S. Liebeskind, M.D. Hill, J. Carrozella, M. Goyal, R. von Kummer, A.M. Demchuk, I. Dzialowski, V. Puetz, T. Jovin, H. Morales, Y.Y. Palesch, J. Broderick, P. Khatri, S.D. Yeatts, for the IMS III Investigators
Outcome Differences between Intra-Arterial Iso- and Low-Osmolality Iodinated Radiographic Contrast Media in the Interventional Management of Stroke III Trial
American Journal of Neuroradiology Nov 2015, 36 (11) 2074-2081; DOI: 10.3174/ajnr.A4421

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Outcome Differences between Intra-Arterial Iso- and Low-Osmolality Iodinated Radiographic Contrast Media in the Interventional Management of Stroke III Trial
T.A. Tomsick, L.D. Foster, D.S. Liebeskind, M.D. Hill, J. Carrozella, M. Goyal, R. von Kummer, A.M. Demchuk, I. Dzialowski, V. Puetz, T. Jovin, H. Morales, Y.Y. Palesch, J. Broderick, P. Khatri, S.D. Yeatts, for the IMS III Investigators
American Journal of Neuroradiology Nov 2015, 36 (11) 2074-2081; DOI: 10.3174/ajnr.A4421
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Cited By...

  • Hemorrhagic Transformation Rates following Contrast Media Administration in Patients Hospitalized with Ischemic Stroke
  • Variable MR and pathologic patterns of hemorrhage after iodinated contrast infusion in MCA occlusion/reperfusion model
  • Reply:
  • Crossref (5)
  • Google Scholar

This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

  • Contrast-induced nephropathy: A dilemma between loss of neurons or nephrons in the setting of endovascular treatment of acute ischemic stroke
    Fernando Delgado Acosta, Elvira Jiménez Gómez, Isabel Bravo Rey, Roberto Valverde Moyano, Francisco de Asís Bravo-Rodriguez, Rafael Oteros Fernández
    Interventional Neuroradiology 2020 26 1
  • Variable MR and pathologic patterns of hemorrhage after iodinated contrast infusion in MCA occlusion/reperfusion model
    Humberto Morales, Aigang Lu, Yuko Kurosawa, Joseph F Clark, Thomas Tomsick
    Journal of NeuroInterventional Surgery 2017 9 12
  • Hemorrhagic Transformation Rates following Contrast Media Administration in Patients Hospitalized with Ischemic Stroke
    F.G. Moser, T.M. Todoran, M. Ryan, E. Baker, C. Gunnarsson, J.A. Kellum
    American Journal of Neuroradiology 2022 43 3
  • Iodinated Contrast Agents Reduce the Efficacy of Intravenous Recombinant Tissue-Type Plasminogen Activator in Acute Ischemic Stroke Patients: a Multicenter Cohort Study
    Zhicai Chen, Chao Xu, Wansi Zhong, Xiaoxian Gong, Haitao Hu, Xuting Zhang, Yi Chen, Qingqing Li, Zhongyu Luo, Zhuojian Chen, Min Lou
    Translational Stroke Research 2021 12 4
  • Reply:
    T.A. Tomsick, D.S. Liebeskind, M.D. Hill, R. von Kummer, M. Goyal, J.P. Broderick
    American Journal of Neuroradiology 2017 38 6

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  • SAVE vs. Solumbra Techniques for Thrombectomy
  • CT Perfusion&Reperfusion in Acute Ischemic Stroke
  • Delayed Reperfusion Post-Thrombectomy&Thrombolysis
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