Do FLAIR Vascular Hyperintensities beyond the DWI Lesion Represent the Ischemic Penumbra?

REFERENCES

1. 1.↵
   2. Azizyan A,
   3. Sanossian N,
   4. Mogensen MA, et al

   . Fluid-attenuated inversion recovery vascular hyperintensities: an important imaging marker for cerebrovascular disease. AJNR Am J Neuroradiol 2011;32:1771–75

   Abstract/FREE Full Text
2. 2.↵
   2. Sanossian N,
   3. Saver JL,
   4. Alger JR, et al

   . Angiography reveals that fluid-attenuated inversion recovery vascular hyperintensities are due to slow flow, not thrombus. AJNR Am J Neuroradiol 2009;30:564–68

   Abstract/FREE Full Text
3. 3.↵
   2. Lee KY,
   3. Latour LL,
   4. Luby M, et al

   . Distal hyperintense vessels on FLAIR: an MRI marker for collateral circulation in acute stroke? Neurology 2009;72:1134–39

   CrossRef
4. 4.↵
   2. Huang X,
   3. Liu W,
   4. Zhu W, et al

   . Distal hyperintense vessels on FLAIR: a prognostic indicator of acute ischemic stroke. Eur Neurol 2012;68:214–20

   CrossRefPubMed
5. 5.↵
   2. Olindo S,
   3. Chausson N,
   4. Joux J, et al

   . Fluid-attenuated inversion recovery vascular hyperintensity: an early predictor of clinical outcome in proximal middle cerebral artery occlusion. Arch Neurol 2012;69:1462–68

   CrossRefPubMed
6. 6.↵
   2. Pérez de la Ossa N,
   3. Hernandez-Perez M,
   4. Domenech S, et al

   . Hyperintensity of distal vessels on FLAIR is associated with slow progression of the infarction in acute ischemic stroke. Cerebrovasc Dis 2012;34:376–84

   CrossRefPubMed
7. 7.↵
   2. Girot M,
   3. Gauvrit JY,
   4. Cordonnier C, et al

   . Prognostic value of hyperintense vessel signals on fluid-attenuated inversion recovery sequences in acute cerebral ischemia. Eur Neurol 2007;57:75–79

   CrossRefPubMed
8. 8.↵
   2. Ebinger M,
   3. Kufner A,
   4. Galinovic I, et al

   . Fluid-attenuated inversion recovery images and stroke outcome after thrombolysis. Stroke 2012;43:539–42

   Abstract/FREE Full Text
9. 9.↵
   2. Cheng B,
   3. Ebinger M,
   4. Kufner A, et al

   . Hyperintense vessels on acute stroke fluid-attenuated inversion recovery imaging: associations with clinical and other MRI findings. Stroke 2012;43:2957–61

   Abstract/FREE Full Text
10. 10.↵
    2. Hohenhaus M,
    3. Schmidt WU,
    4. Brunecker P, et al

    . FLAIR vascular hyperintensities in acute ICA and MCA infarction: a marker for mismatch and stroke severity? Cerebrovasc Dis 2012;34:63–69

    CrossRefPubMed
11. 11.↵
    2. Schellinger PD,
    3. Chalela JA,
    4. Kang DW, et al

    . Diagnostic and prognostic value of early MR imaging vessel signs in hyperacute stroke patients imaged <3 hours and treated with recombinant tissue plasminogen activator. AJNR Am J Neuroradiol 2005;26:618–24

    Abstract/FREE Full Text
12. 12.↵
    2. Kamran S,
    3. Bates V,
    4. Bakshi R, et al

    . Significance of hyperintense vessels on FLAIR MRI in acute stroke. Neurology 2000;55:265–69

    CrossRef
13. 13.↵
    2. Haussen DC,
    3. Koch S,
    4. Saraf-Lavi E, et al

    . FLAIR distal hyperintense vessels as a marker of perfusion-diffusion mismatch in acute stroke. J Neuroimaging 2013;23:397–400

    CrossRefPubMed
14. 14.↵
    2. Toyoda K,
    3. Ida M,
    4. Fukuda K

    . Fluid-attenuated inversion recovery intraarterial signal: an early sign of hyperacute cerebral ischemia. AJNR Am J Neuroradiol 2001;22:1021–29

    Abstract/FREE Full Text
15. 15.↵
    2. Cosnard G,
    3. Duprez T,
    4. Grandin C, et al

    . Fast FLAIR sequence for detecting major vascular abnormalities during the hyperacute phase of stroke: a comparison with MR angiography. Neuroradiology 1999;41:342–46

    CrossRefPubMedWeb of Science
16. 16.↵
    2. Bang OY,
    3. Saver JL,
    4. Kim SJ, et al

    . Collateral flow predicts response to endovascular therapy for acute ischemic stroke. Stroke 2011;42:693–99

    Abstract/FREE Full Text
17. 17.↵
    2. Maeda M,
    3. Koshimoto Y,
    4. Uematsu H, et al

    . Time course of arterial hyperintensity with fast fluid-attenuated inversion-recovery imaging in acute and subacute middle cerebral arterial infarction. J Magn Reson Imaging 2001;13:987–90

    CrossRefPubMed
18. 18.↵
    2. Labeyrie MA,
    3. Turc G,
    4. Hess A, et al

    . Diffusion lesion reversal after thrombolysis: a MR correlate of early neurological improvement. Stroke 2012;43:2986–91

    Abstract/FREE Full Text
19. 19.↵
    2. Lansberg MG,
    3. Straka M,
    4. Kemp S, et al

    . MRI profile and response to endovascular reperfusion after stroke (DEFUSE 2): a prospective cohort study. Lancet Neurol 2012;11:860–67

    CrossRefPubMedWeb of Science
20. 20.↵
    2. Kono T,
    3. Naka H,
    4. Nomura E, et al

    . The association between hyperintense vessel sign and final ischemic lesion differ in its location. J Stroke Cerebrovasc Dis 2014;23:1337–43

    CrossRefPubMed
21. 21.↵
    2. Gawlitza M,
    3. Gragert J,
    4. Quaschling U, et al

    . FLAIR-hyperintense vessel sign, diffusion-perfusion mismatch and infarct growth in acute ischemic stroke without vascular recanalisation therapy. J Neuroradiol 2014;41:227–33

    CrossRefPubMed
22. 22.↵
    2. Liu W,
    3. Xu G,
    4. Yue X, et al

    . Hyperintense vessels on FLAIR: a useful non-invasive method for assessing intracerebral collaterals. Eur J Radiol 2011;80:786–91

    CrossRefPubMed
23. 23.↵
    2. Muir KW,
    3. Buchan A,
    4. von Kummer R, et al

    . Imaging of acute stroke. Lancet Neurol 2006;5:755–68

    CrossRefPubMedWeb of Science
24. 24.↵
    2. Donnan GA,
    3. Baron JC,
    4. Ma H, et al

    . Penumbral selection of patients for trials of acute stroke therapy. Lancet Neurol 2009;8:261–69

    CrossRefPubMedWeb of Science