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Research ArticleBrain
Open Access

Diffusion and Perfusion MRI to Differentiate Treatment-Related Changes Including Pseudoprogression from Recurrent Tumors in High-Grade Gliomas with Histopathologic Evidence

A.J. Prager, N. Martinez, K. Beal, A. Omuro, Z. Zhang and R.J. Young
American Journal of Neuroradiology May 2015, 36 (5) 877-885; DOI: https://doi.org/10.3174/ajnr.A4218
A.J. Prager
aFrom the Departments of Radiology (A.J.P., R.J.Y.)
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N. Martinez
bNeurology (N.M., A.O.)
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K. Beal
cRadiation Oncology (K.B.)
ethe Brain Tumor Center (K.B., A.O., R.J.Y.), Memorial Sloan Kettering Cancer Center, New York, New York.
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A. Omuro
bNeurology (N.M., A.O.)
ethe Brain Tumor Center (K.B., A.O., R.J.Y.), Memorial Sloan Kettering Cancer Center, New York, New York.
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Z. Zhang
dEpidemiology and Biostatistics (Z.Z.)
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R.J. Young
aFrom the Departments of Radiology (A.J.P., R.J.Y.)
ethe Brain Tumor Center (K.B., A.O., R.J.Y.), Memorial Sloan Kettering Cancer Center, New York, New York.
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American Journal of Neuroradiology: 36 (5)
American Journal of Neuroradiology
Vol. 36, Issue 5
1 May 2015
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Cite this article
A.J. Prager, N. Martinez, K. Beal, A. Omuro, Z. Zhang, R.J. Young
Diffusion and Perfusion MRI to Differentiate Treatment-Related Changes Including Pseudoprogression from Recurrent Tumors in High-Grade Gliomas with Histopathologic Evidence
American Journal of Neuroradiology May 2015, 36 (5) 877-885; DOI: 10.3174/ajnr.A4218

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Diffusion and Perfusion MRI to Differentiate Treatment-Related Changes Including Pseudoprogression from Recurrent Tumors in High-Grade Gliomas with Histopathologic Evidence
A.J. Prager, N. Martinez, K. Beal, A. Omuro, Z. Zhang, R.J. Young
American Journal of Neuroradiology May 2015, 36 (5) 877-885; DOI: 10.3174/ajnr.A4218
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  • "Synthetic" DSC Perfusion MRI with Adjustable Acquisition Parameters in Brain Tumors Using Dynamic Spin-and-Gradient-Echo Echoplanar Imaging
  • Identification of a Single-Dose, Low-Flip-Angle-Based CBV Threshold for Fractional Tumor Burden Mapping in Recurrent Glioblastoma
  • Arterial Spin-Labeling and DSC Perfusion Metrics Improve Agreement in Neuroradiologists Clinical Interpretations of Posttreatment High-Grade Glioma Surveillance MR Imaging--An Institutional Experience
  • Volumetric Measurement of Relative CBV Using T1-Perfusion-Weighted MRI with High Temporal Resolution Compared with Traditional T2*-Perfusion-Weighted MRI in Postoperative Patients with High-Grade Gliomas
  • Spatiotemporal Heterogeneity in Multiparametric Physiologic MRI Is Associated with Patient Outcomes in IDH-Wildtype Glioblastoma
  • Centrally Reduced Diffusion Sign for Differentiation between Treatment-Related Lesions and Glioma Progression: A Validation Study
  • Diagnostic Performance of PET and Perfusion-Weighted Imaging in Differentiating Tumor Recurrence or Progression from Radiation Necrosis in Posttreatment Gliomas: A Review of Literature
  • 18F-FET PET Imaging in Differentiating Glioma Progression from Treatment-Related Changes: A Single-Center Experience
  • Response Assessment in Neuro-Oncology Criteria for Gliomas: Practical Approach Using Conventional and Advanced Techniques
  • Perfusion MRI-Based Fractional Tumor Burden Differentiates between Tumor and Treatment Effect in Recurrent Glioblastomas and Informs Clinical Decision-Making
  • Utility of Dynamic Susceptibility Contrast Perfusion-Weighted MR Imaging and 11C-Methionine PET/CT for Differentiation of Tumor Recurrence from Radiation Injury in Patients with High-Grade Gliomas
  • Multiparametric Evaluation in Differentiating Glioma Recurrence from Treatment-Induced Necrosis Using Simultaneous 18F-FDG-PET/MRI: A Single-Institution Retrospective Study
  • A Simple Automated Method for Detecting Recurrence in High-Grade Glioma
  • Osseous Pseudoprogression in Vertebral Bodies Treated with Stereotactic Radiosurgery: A Secondary Analysis of Prospective Phase I/II Clinical Trials
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