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Aneurysm Characteristics Anterior ICA ≥10 mm Anterior ICA <10 mm Posterior Other Anterior P Value Total Aneurysm size (mm) <.0001 Mean ± SD (n) 16.8 ± 6.3 (317) 5.2 ± 2.2 (360) 13.8 ± 8.4 (93) 9.2 ± 8.0 (126) 10.7 ± 7.7 (896) Median, range 15.0, 10.0–42.0 5.0, 1.0–10.0 11.6, 1.5–45.0 6.7, 1.0–55.0 9.0, 1.0–55.0 Aneurysm type <.0001 Small 0.0% (0/317) 100.0% (360/360) 35.5% (33/93) 63.5% (80/126) 52.8% (473/896) Large 85.8% (272/317) 0.0% (0/360) 49.5% (46/93) 31.0% (39/126) 39.8% (357/896) Giant 14.2% (45/317) 0.0% (0/360) 15.1% (14/93) 5.6% (7/126) 7.4% (66/896) Aneurysm neck (mm) <.0001 Mean ± SD (n) 8.5 ± 5.0 (297) 4.1 ± 2.2 (335) 8.7 ± 7.5 (70) 4.8 ± 5.1 (110) 6.2 ± 4.9 (812) Median, range 7.6, 0.9–50.0 3.9, 0.8–22.0 6.6, 1.7–53.0 3.9, 1.0–50.0 5.0, 0.8–53.0 Aneurysm shape <.0001 Saccular 77.3% (245/317) 87.8% (316/360) 35.8% (34/95) 71.7% (91/127) 76.0% (689/906) Fusiform 15.5% (49/317) 4.7% (17/360) 29.5% (28/95) 15.0% (19/127) 12.8% (116/906) Dissecting 3.2% (10/317) 2.2% (8/360) 28.4% (27/95) 7.1% (9/127) 6.0% (54/906) Other 4.1% (13/317) 5.3% (19/360) 6.3% (6/95) 6.3% (8/127) 5.2% (47/906) Aneurysm location <.0001 Internal carotid artery 100.0% (317/317) 100.0% (360/360) 0.0% (0/95) 0.0% (0/127) 75.5% (684/906) Middle cerebral artery 0.0% (0/317) 0.0% (0/360) 0.0% (0/95) 33.9% (43/127) 4.7% (43/906) Posterior cerebral artery 0.0% (0/317) 0.0% (0/360) 15.8% (15/95) 0.0% (0/127) 1.7% (15/906) Basilar artery 0.0% (0/317) 0.0% (0/360) 46.3% (44/95) 0.0% (0/127) 4.9% (44/906) Other 0.0% (0/317) 0.0% (0/360) 37.9% (36/95) 66.1% (84/127) 13.2% (120/906) Presented with ruptured aneurysm 3.8% (12/317) 6.7% (24/360) 7.4% (7/95) 25.2% (32/127) <.0001 8.4% (76/906) Multiple PEDs utilized 45.4% (144/317) 27.4% (98/358) 37.9% (36/95) 22.8% (29/127) <.0001 34.1% (308/904) Patient Characteristics Anterior ICA ≥10 mm Anterior ICA <10 mm Posterior Other Anterior P Value Total 95% CI Aneurysm size (mm) <.0001 (10.7–11.8) Mean ± SD (n) 16.8 ± 6.3 (296) 5.3 ± 2.2 (291) 14.2 ± 8.5 (88) 9.7 ± 8.3 (112) 11.2 ± 7.8 (787) Median, range 15.0, 10.0–42.0 5.0, 1.2–10.0 12.0, 1.5–45.0 7.1, 1.0–55.0 10.0, 1.0–55.0 Spontaneous rupture 1.4% (4/296) 0.0% (0/291) 1.1% (1/90) 0.0% (0/112) .1657 0.6% (5/793) (0.2%–1.5%) Intracranial hemorrhage 2.7% (8/296) 1.4% (4/291) 2.2% (2/90) 5.4% (6/112) .2299 2.5% (20/793) (1.6%–3.9%) Ischemic stroke 5.4% (16/296) 2.4% (7/291) 6.7% (6/90) 6.3% (7/112) .1726 4.5% (36/793) (3.2%–6.2%) Parent artery stenosis 0.3% (1/296) 0.3% (1/291) 0.0% (0/90) 0.0% (0/112) 1.0000 0.3% (2/793) (0.0%–0.9%) Cranial neuropathy 0.7% (2/296) 0.0% (0/291) 0.0% (0/90) 0.0% (0/112) .7257 0.3% (2/793) (0.0%–0.9%) Neurologic morbidity 8.8% (26/296) 4.1% (12/291) 8.9% (8/90) 11.6% (13/112) .0496 7.4% (59/793) (5.7%–9.5%) Neurologic mortality 3.7% (11/296) 1.4% (4/291) 7.8% (7/90) 7.1% (8/112) .0108 3.8% (30/793) (2.6%–5.4%) Neurologic morbidity and mortality (all patients) 9.5% (28/296) 4.1% (12/291) 13.3% (12/90) 13.4% (15/112) .0046 8.4% (67/793) (6.6%–10.6%) Neurologic morbidity and mortality (patients with unruptured aneurysms) 9.5% (27/285) 3.4% (9/268) 12.0% (10/83) 9.9% (8/81) .0104 7.5% (54/720) (5.7%–9.7%) Neurologic morbidity and mortality (patients with ruptured aneurysms) 16.7% (2/12) 12.5% (3/24) 28.6% (2/7) 21.9% (7/32) .7639 18.4% (14/76) (10.5%–29.0%) Neurologic morbidity and mortality (excluding ruptured, dissecting, or fusiform aneurysms) 7.7% (18/233) 3.6% (9/253) 8.6% (3/35) 9.7% (6/62) .1343 6.2% (36/585) (4.4%–8.4%) Major Complications <72 Hours 72 Hours–30 Days >30 Days P Value Total Anterior Posterior Anterior Posterior Anterior Posterior Spontaneous rupture 0.1% (1/703) 0.0% (0/90) 0.3% (2/703) 1.1% (1/90) 0.1% (1/703) 0.0% (0/90) .6290 0.6% (5/793) Intracranial hemorrhage 0.4% (3/703) 2.2% (2/90) 1.6% (11/703) 0.0% (0/90) 0.6% (4/703) 0.0% (0/90) .1363 2.5% (20/793) Ischemic stroke 2.1% (15/703) 3.3% (3/90) 0.9% (6/703) 2.2% (2/90) 1.3% (9/703) 1.1% (1/90) .1102 4.5% (36/793) Parent artery stenosis 0.0% (0/703) 0.0% (0/90) 0.1% (1/703) 0.0% (0/90) 0.1% (1/703) 0.0% (0/90) 1.0000 0.3% (2/793) Cranial neuropathy 0.0% (0/703) 0.0% (0/90) 0.3% (2/703) 0.0% (0/90) 0.0% (0/703) 0.0% (0/90) .3331 0.3% (2/793) Neurologic morbidity 2.6% (18/703) 5.6% (5/90) 2.8% (20/703) 2.2% (2/90) 1.8% (13/703) 1.1% (1/90) .2757 7.4% (59/793) Neurologic mortality 1.0% (7/703) 3.3% (3/90) 1.4% (10/703) 2.2% (2/90) 0.9% (6/703) 2.2% (2/90) .7014 3.8% (30/793) Neurologic morbidity and mortality (all patients) 2.8% (20/703) 5.6% (5/90) 3.1% (22/703) 4.4% (4/90) 1.8% (13/703) 3.3% (3/90) .2543 8.4% (67/793) Neurologic morbidity and mortality (patients with unruptured aneurysms) 2.5% (16/637) 6.0% (5/83) 2.7% (17/637) 3.6% (3/83) 1.7% (11/637) 2.4% (2/83) .3511 7.5% (54/720) Neurologic morbidity and mortality (patients with ruptured aneurysms) 5.8% (4/69) 0.0% (0/7) 8.7% (6/69) 14.3% (1/7) 2.9% (2/69) 14.3% (1/7) .4768 18.4% (14/76) Neurologic morbidity and mortality (excluding ruptured, dissecting, or fusiform aneurysms) 2.5% (14/550) 2.9% (1/35) 2.5% (14/550) 2.9% (1/35) 0.9% (5/550) 2.9% (1/35) .0934 6.2% (36/585) Major Complications Small Large Giant P Value Total Anterior Posterior Anterior Posterior Anterior Posterior Aneurysm size (mm) <.0001 Mean ± SD (n) 5.3 ± 2.2 (360) 6.1 ± 2.5 (27) 14.8 ± 4.1 (292) 14.8 ± 4.1 (46) 29.2 ± 5.6 (49) 28.5 ± 6.2 (14) 11.3 ± 7.7 (788) Median, range 5.0, 1.0–10.0 6.3, 1.5–9.4 14.0, 10.0–24.5 14.3, 10.0–23.0 27.0, 25.0–55.0 26.0, 25.0–45.0 10.0, 1.0–55.0 Spontaneous rupture 0.0% (0/360) 0.0% (0/27) 0.7% (2/292) 0.0% (0/46) 4.1% (2/49) 7.1% (1/14) .0011 0.6% (5/793) Intracranial hemorrhage 1.9% (7/360) 0.0% (0/27) 2.7% (8/292) 2.2% (1/46) 6.1% (3/49) 7.1% (1/14) .0901 2.5% (20/793) Ischemic stroke 2.8% (10/360) 0.0% (0/27) 4.8% (14/292) 4.3% (2/46) 12.2% (6/49) 21.4% (3/14) .0008 4.5% (36/793) Parent artery stenosis 0.3% (1/360) 0.0% (0/27) 0.3% (1/292) 0.0% (0/46) 0.0% (0/49) 0.0% (0/14) 1.0000 0.3% (2/793) Cranial neuropathy 0.0% (0/360) 0.0% (0/27) 0.7% (2/292) 0.0% (0/46) 0.0% (0/49) 0.0% (0/14) .3373 0.3% (2/793) Neurologic morbidity 5.0% (18/360) 0.0% (0/27) 7.5% (22/292) 6.5% (3/46) 22.4% (11/49) 28.6% (4/14) <.0001 7.4% (59/793) Neurologic mortality 1.7% (6/360) 3.7% (1/27) 4.8% (14/292) 6.5% (3/46) 6.1% (3/49) 21.4% (3/14) .0033 3.8% (30/793) Neurologic morbidity and mortality (all patients) 5.3% (19/360) 3.7% (1/27) 8.6% (25/292) 10.9% (5/46) 22.4% (11/49) 35.7% (5/14) <.0001 8.4% (67/793) Neurologic morbidity and mortality (patients with unruptured aneurysms) 3.5% (11/311) 0.0% (0/24) 7.9% (22/277) 11.4% (5/44) 22.9% (11/48) 30.8% (4/13) <.0001 7.5% (54/720) Neurologic morbidity and mortality (patients with ruptured aneurysms) 16.0% (8/50) 33.3% (1/3) 18.8% (3/16) 0.0% (0/2) 50.0% (1/2) 100.0% (1/1) .1385 18.4% (14/76) Neurologic morbidity and mortality (excluding ruptured, dissecting, or fusiform aneurysms) 3.8% (11/293) 0.0% (0/12) 6.4% (14/218) 11.8% (2/17) 20.5% (8/39) 20.0% (1/5) .0005 6.2% (36/585)
