Longitudinal Mixed-Effect Model Analysis of the Association between Global and Tissue-Specific Brain Atrophy and Lesion Accumulation in Patients with Clinically Isolated Syndrome

M. Varosanec; T. Uher; D. Horakova; J. Hagemeier; N. Bergsland; M. Tyblova; Z. Seidl; M. Vaneckova; J. Krasensky; M.G. Dwyer; E. Havrdova; R. Zivadinov

doi:10.3174/ajnr.A4330

Research ArticleAdult Brain

Open Access

Longitudinal Mixed-Effect Model Analysis of the Association between Global and Tissue-Specific Brain Atrophy and Lesion Accumulation in Patients with Clinically Isolated Syndrome

M. Varosanec, T. Uher, D. Horakova, J. Hagemeier, N. Bergsland, M. Tyblova, Z. Seidl, M. Vaneckova, J. Krasensky, M.G. Dwyer, E. Havrdova and R. Zivadinov

American Journal of Neuroradiology August 2015, 36 (8) 1457-1464; DOI: https://doi.org/10.3174/ajnr.A4330

M. Varosanec

aFrom the Buffalo Neuroimaging Analysis Center (M.V., T.U., J.H., N.B., M.G.D., R.Z.), Department of Neurology, University at Buffalo SUNY, Buffalo, New York

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

T. Uher

aFrom the Buffalo Neuroimaging Analysis Center (M.V., T.U., J.H., N.B., M.G.D., R.Z.), Department of Neurology, University at Buffalo SUNY, Buffalo, New York

bDepartment of Neurology and Center of Clinical Neuroscience (T.U., D.H., M.T., E.H.)

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

D. Horakova

bDepartment of Neurology and Center of Clinical Neuroscience (T.U., D.H., M.T., E.H.)

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

J. Hagemeier

aFrom the Buffalo Neuroimaging Analysis Center (M.V., T.U., J.H., N.B., M.G.D., R.Z.), Department of Neurology, University at Buffalo SUNY, Buffalo, New York

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

N. Bergsland

aFrom the Buffalo Neuroimaging Analysis Center (M.V., T.U., J.H., N.B., M.G.D., R.Z.), Department of Neurology, University at Buffalo SUNY, Buffalo, New York

dIRCCS “Santa Maria Nascente” (N.B.), Don Gnocchi Foundation, Milan, Italy.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for N. Bergsland

M. Tyblova

bDepartment of Neurology and Center of Clinical Neuroscience (T.U., D.H., M.T., E.H.)

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Z. Seidl

cDepartment of Radiology (Z.S., M.V., J.K.), Charles University in Prague, First Faculty of Medicine and General University Hospital, Prague, Czech Republic

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

M. Vaneckova

cDepartment of Radiology (Z.S., M.V., J.K.), Charles University in Prague, First Faculty of Medicine and General University Hospital, Prague, Czech Republic

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

J. Krasensky

cDepartment of Radiology (Z.S., M.V., J.K.), Charles University in Prague, First Faculty of Medicine and General University Hospital, Prague, Czech Republic

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

M.G. Dwyer

aFrom the Buffalo Neuroimaging Analysis Center (M.V., T.U., J.H., N.B., M.G.D., R.Z.), Department of Neurology, University at Buffalo SUNY, Buffalo, New York

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

E. Havrdova

bDepartment of Neurology and Center of Clinical Neuroscience (T.U., D.H., M.T., E.H.)

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

R. Zivadinov

aFrom the Buffalo Neuroimaging Analysis Center (M.V., T.U., J.H., N.B., M.G.D., R.Z.), Department of Neurology, University at Buffalo SUNY, Buffalo, New York

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Article
Figures & Data
Info & Metrics
Responses
References
PDF

Submit a Response to This Article

Compose eLetter

Title *

Contents

More information about text formats

Plain text

No HTML tags allowed.
Web page addresses and e-mail addresses turn into links automatically.
Lines and paragraphs break automatically.

Author Information

Contributors
First Name and Middle Initial * First or given name, e.g. 'Peter'. Last Name * Your last, or family, name, e.g. 'MacMoody'. Email Address * Your email address, e.g. higgs-boson@gmail.com Occupation * Your role and/or occupation, e.g. 'Orthopedic Surgeon'. Affiliation * Your organization or institution (if applicable), e.g. 'Royal Free Hospital'.

Statement of Competing Interests

Competing interests? *

Yes

Please describe the competing interests

Vertical Tabs

Jump to comment:

No eLetters have been published for this article.

PreviousNext

In this issue

American Journal of Neuroradiology

Vol. 36, Issue 8

1 Aug 2015

Table of Contents
Index by author
Complete Issue (PDF)

Download PDF

Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Your Email *

Your Name *

Send To *

Enter multiple addresses on separate lines or separate them with commas.

You are going to email the following Longitudinal Mixed-Effect Model Analysis of the Association between Global and Tissue-Specific Brain Atrophy and Lesion Accumulation in Patients with Clinically Isolated Syndrome

Message Subject (Your Name) has sent you a message from American Journal of Neuroradiology

Message Body (Your Name) thought you would like to see the American Journal of Neuroradiology web site.

Your Personal Message

CAPTCHA

This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

Cite this article

M. Varosanec, T. Uher, D. Horakova, J. Hagemeier, N. Bergsland, M. Tyblova, Z. Seidl, M. Vaneckova, J. Krasensky, M.G. Dwyer, E. Havrdova, R. Zivadinov

Longitudinal Mixed-Effect Model Analysis of the Association between Global and Tissue-Specific Brain Atrophy and Lesion Accumulation in Patients with Clinically Isolated Syndrome

American Journal of Neuroradiology Aug 2015, 36 (8) 1457-1464; DOI: 10.3174/ajnr.A4330

Citation Manager Formats

BibTeX
Bookends
EasyBib
EndNote (tagged)
EndNote 8 (xml)
Medlars
Mendeley
Papers
RefWorks Tagged
Ref Manager
RIS
Zotero

0 Responses

Respond to this article

Bookmark this article

User Name *

Password *

Remember my user name & password.

Longitudinal Mixed-Effect Model Analysis of the Association between Global and Tissue-Specific Brain Atrophy and Lesion Accumulation in Patients with Clinically Isolated Syndrome

M. Varosanec, T. Uher, D. Horakova, J. Hagemeier, N. Bergsland, M. Tyblova, Z. Seidl, M. Vaneckova, J. Krasensky, M.G. Dwyer, E. Havrdova, R. Zivadinov

American Journal of Neuroradiology Aug 2015, 36 (8) 1457-1464; DOI: 10.3174/ajnr.A4330

Share This Article:

Tweet Widget
Facebook Like
Google Plus One

Purchase

Jump to section

Article
Figures & Data
Info & Metrics
Responses
References
PDF

PubMed
Google Scholar

Cited By...

FEMA: Fast and efficient mixed-effects algorithm for large sample whole-brain imaging data
Evolution of Brain Volume Loss Rates in Early Stages of Multiple Sclerosis
Brain and White Matter Hyperintensity Volumes After 10 Years of Random Assignment to Lifestyle Intervention

Crossref (13)
Google Scholar

This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

Brain and White Matter Hyperintensity Volumes After 10 Years of Random Assignment to Lifestyle Intervention

Mark A. Espeland, Kirk Erickson, Rebecca H. Neiberg, John M. Jakicic, Thomas A. Wadden, Rena R. Wing, Lisa Desiderio, Guray Erus, Meng-Kang Hsieh, Christos Davatzikos, Barbara J. Maschak-Carey, Paul J. Laurienti, Kathryn Demos-McDermott, R. Nick Bryan

Diabetes Care 2016 39 5
Atorvastatin Treatment of Cavernous Angiomas with Symptomatic Hemorrhage Exploratory Proof of Concept (AT CASH EPOC) Trial

Sean P Polster, Agnieszka Stadnik, Amy L Akers, Ying Cao, Gregory A Christoforidis, Maged D Fam, Kelly D Flemming, Romuald Girard, Nicholas Hobson, James I Koenig, Janne Koskimäki, Karen Lane, James K Liao, Cornelia Lee, Seán B Lyne, Nichol McBee, Leslie Morrison, Kristina Piedad, Robert Shenkar, Matthew Sorrentino, Richard E Thompson, Kevin J Whitehead, Hussein A Zeineddine, Daniel F Hanley, Issam A Awad

Neurosurgery 2019 85 6
Identification of multiple sclerosis patients at highest risk of cognitive impairment using an integrated brain magnetic resonance imaging assessment approach

T. Uher, M. Vaneckova, M. P. Sormani, J. Krasensky, L. Sobisek, J. Blahova Dusankova, Z. Seidl, E. Havrdova, T. Kalincik, R. H. B. Benedict, D. Horakova

European Journal of Neurology 2017 24 2
Evolution of Brain Volume Loss Rates in Early Stages of Multiple Sclerosis

Tomas Uher, Jan Krasensky, Charles Malpas, Niels Bergsland, Michael G. Dwyer, Eva Kubala Havrdova, Manuela Vaneckova, Dana Horakova, Robert Zivadinov, Tomas Kalincik

Neurology Neuroimmunology & Neuroinflammation 2021 8 3
Imaging in mice and men: Pathophysiological insights into multiple sclerosis from conventional and advanced MRI techniques

Julia Krämer, Wolfgang Brück, Frauke Zipp, Manuela Cerina, Sergiu Groppa, Sven G. Meuth

Progress in Neurobiology 2019 182
New and enlarging white matter lesions adjacent to the ventricle system and thalamic atrophy are independently associated with lateral ventricular enlargement in multiple sclerosis

Tim Sinnecker, Esther Ruberte, Sabine Schädelin, Vera Canova, Michael Amann, Yvonne Naegelin, Iris-Katharina Penner, Jannis Müller, Jens Kuhle, Bernhard Décard, Tobias Derfuss, Ludwig Kappos, Cristina Granziera, Jens Wuerfel, Stefano Magon, Özgür Yaldizli

Journal of Neurology 2020 267 1
Predictive MRI Biomarkers in MS—A Critical Review

Vlad Eugen Tiu, Iulian Enache, Cristina Aura Panea, Cristina Tiu, Bogdan Ovidiu Popescu

Medicina 2022 58 3
FEMA: Fast and efficient mixed‐effects algorithm for large sample whole‐brain imaging data

Pravesh Parekh, Chun Chieh Fan, Oleksandr Frei, Clare E. Palmer, Diana M. Smith, Carolina Makowski, John R. Iversen, Diliana Pecheva, Dominic Holland, Robert Loughnan, Pierre Nedelec, Wesley K. Thompson, Donald J. Hagler, Ole A. Andreassen, Terry L. Jernigan, Thomas E. Nichols, Anders M. Dale

Human Brain Mapping 2024 45 2
The spatio-temporal relationship between white matter lesion volume changes and brain atrophy in clinically isolated syndrome and early multiple sclerosis

Rozemarijn M. Mattiesing, Giordano Gentile, Iman Brouwer, Ronald A. van Schijndel, Bernard M.J. Uitdehaag, Jos W.R. Twisk, Ludwig Kappos, Mark S. Freedman, Giancarlo Comi, Dominic Jack, Nicola De Stefano, Frederik Barkhof, Marco Battaglini, Hugo Vrenken

NeuroImage: Clinical 2022 36
What do we currently know about the clinically isolated syndrome suggestive of multiple sclerosis? An update

Tomasz Grzegorski, Jacek Losy

Reviews in the Neurosciences 2020 31 3

Main menu

User menu

Search

American Journal of Neuroradiology

Longitudinal Mixed-Effect Model Analysis of the Association between Global and Tissue-Specific Brain Atrophy and Lesion Accumulation in Patients with Clinically Isolated Syndrome

Plain text

Vertical Tabs

Jump to comment:

In this issue

Citation Manager Formats

Related Articles

Cited By...

More in this TOC Section

Similar Articles

Indexed Content

Cases

Special Collections

Resources

Multimedia

About Us

American Society of Neuroradiology