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Research ArticleHEAD & NECK

High-Resolution MRI Findings following Trigeminal Rhizotomy

B.G. Northcutt, D.P. Seeburg, J. Shin, N. Aygun, D.A. Herzka, D. Theodros, C.R. Goodwin, C. Bettegowda, M. Lim and A.M. Blitz
American Journal of Neuroradiology October 2016, 37 (10) 1920-1924; DOI: https://doi.org/10.3174/ajnr.A4868
B.G. Northcutt
aFrom the Departments of Radiology and Radiologic Sciences, Division of Neuroradiology (B.G.N., D.P.S., J.S., N.A., A.M.B.)
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  • ORCID record for B.G. Northcutt
D.P. Seeburg
aFrom the Departments of Radiology and Radiologic Sciences, Division of Neuroradiology (B.G.N., D.P.S., J.S., N.A., A.M.B.)
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J. Shin
aFrom the Departments of Radiology and Radiologic Sciences, Division of Neuroradiology (B.G.N., D.P.S., J.S., N.A., A.M.B.)
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N. Aygun
aFrom the Departments of Radiology and Radiologic Sciences, Division of Neuroradiology (B.G.N., D.P.S., J.S., N.A., A.M.B.)
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D.A. Herzka
bBiomedical Engineering (D.A.H.)
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D. Theodros
cNeurosurgery (D.T., C.R.G., C.B., M.L.), Johns Hopkins Hospital, Baltimore, Maryland.
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C.R. Goodwin
cNeurosurgery (D.T., C.R.G., C.B., M.L.), Johns Hopkins Hospital, Baltimore, Maryland.
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C. Bettegowda
cNeurosurgery (D.T., C.R.G., C.B., M.L.), Johns Hopkins Hospital, Baltimore, Maryland.
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M. Lim
cNeurosurgery (D.T., C.R.G., C.B., M.L.), Johns Hopkins Hospital, Baltimore, Maryland.
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A.M. Blitz
aFrom the Departments of Radiology and Radiologic Sciences, Division of Neuroradiology (B.G.N., D.P.S., J.S., N.A., A.M.B.)
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Article Figures & Data

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  • Fig 1.
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    Fig 1.

    Coronal CISS precontrast images at the level of Meckel's cave. A, Decreased T2 signal intensity and poorly delineated nerve rootlets in the left Meckel's cave after rhizotomy. Note a normal-appearing right Meckel's cave. B, A different patient with clumping of the nerve rootlets inferiorly within the left Meckel's cave post-rhizotomy. C, Central clumping of nerve rootlets in the right Meckel's cave post-rhizotomy. D, A different patient with more subtle clumping of the nerve rootlets in the left Meckel's cave and subtle decreased CISS SI post-rhizotomy.

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    Fig 2.

    Graph showing the ratio of CISS SI of the right and left Meckel's caves in control patients and rhizotomy/nonrhizotomy in Meckel's caves in post-rhizotomy patients. The control group ratio was 0.99 compared with 0.87 for patients who underwent rhizotomy (P < .001).

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    Fig 3.

    Coronal CISS precontrast at the level of Meckel's caves. Encephalomalacia of the medial left temporal lobe (straight arrow) adjacent to Meckel's cave. Also note clumping of the nerve rootlets in the left Meckel's cave (curved arrow) status post rhizotomy.

Tables

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    Table 1:

    Subject age and sex

    Post-RhizotomyTreatment-NaïveP Value
    No. of Subjects2654
    Age (mean) (range) (yr)60 (27–85)55 (29–74).09
    Sex6 Men, 20 women20 Men, 34 women.31
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    Table 2:

    Frequency of findings within Meckel's cave in treatment-naïve versus post-rhizotomy patientsa

    Post-RhizotomyTreatment-NaïveP Value
    Subjective clumping16/26 (62%)3/54 (6%)<.001
    Decreased CISS13/26 (50%)3/54 (6%)<.001
    Subjective clumping without decreased CISS SI4/26 (15%)0/54 (0%).01
    ↓ CISS SI without clumping1/26 (4%)0/54 (0%).33
    Subjective nerve clumping and ↓ CISS SI12/26 (46%)3/54 (6%)<.001
    Subjective nerve clumping and/or ↓ CISS SI17/26 (65%)3/54 (6%)<.001
    • Note:—↓ indicates decrease.

    • ↵a Interobserver agreement = 90%, κ = 0.69.

    • View popup
    Table 3:

    Ratio of CISS SI in treatment-naïve versus post-rhizotomy patients

    Control Right MC/Left MC (mean ratio ± SD)Rhizotomy MC/Contralateral MC (mean ratio ± SD)P Value
    Ratio of CISS SI0.99 (±0.09)0.87 (±0.15)<.001
    • Note:—MC indicates Meckel cave.

    • View popup
    Table 4:

    Frequency of findings in the adjacent structures in treatment-naïve versus post-rhizotomy patients

    Post-RhizotomyTreatment-NaïveP ValueInterobserver Agreementκ
    Encephalomalacia8/26 (31%)0/54 (0%)<.00198.8%0.93
    Hematoma1/26 (4%)0/54 (0%).33100%1
    Atrophy of muscles of mastication3/26 (10%)3/54 (4%).3896.3%0.64
    CN V enhancement0/26 (0%)0/54 (0%)1.00100%1
    Vascular injury0/26 (0%)0/54 (0%)1.00100%1
    • Note:—CN indicates cranial nerve.

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American Journal of Neuroradiology: 37 (10)
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Cite this article
B.G. Northcutt, D.P. Seeburg, J. Shin, N. Aygun, D.A. Herzka, D. Theodros, C.R. Goodwin, C. Bettegowda, M. Lim, A.M. Blitz
High-Resolution MRI Findings following Trigeminal Rhizotomy
American Journal of Neuroradiology Oct 2016, 37 (10) 1920-1924; DOI: 10.3174/ajnr.A4868

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High-Resolution MRI Findings following Trigeminal Rhizotomy
B.G. Northcutt, D.P. Seeburg, J. Shin, N. Aygun, D.A. Herzka, D. Theodros, C.R. Goodwin, C. Bettegowda, M. Lim, A.M. Blitz
American Journal of Neuroradiology Oct 2016, 37 (10) 1920-1924; DOI: 10.3174/ajnr.A4868
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