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Index by author

November 01, 2016; Volume 37,Issue 11

  1. Blumenthal, D.T.

    1. EDITOR'S CHOICEADULT BRAIN
      Early Biomarkers from Conventional and Delayed-Contrast MRI to Predict the Response to Bevacizumab in Recurrent High-Grade Gliomas
      D. Daniels, D. Guez, D. Last, C. Hoffmann, D. Nass, A. Talianski, G. Tsarfaty, S. Salomon, A.A. Kanner, D.T. Blumenthal, F. Bokstein, S. Harnof, D. Yekutieli, S. Zamir, Z.R. Cohen, L. Zach and Y. Mardor
      American Journal of Neuroradiology November 2016, 37 (11) 2003-2009; DOI: https://doi.org/10.3174/ajnr.A4866

      Twenty-four patients with recurrent high-grade gliomas were scanned before and during bevacizumab treatment with standard and delayed-contrast MRI. The mean change in lesion volumes of responders (overall survival, >1 year) and nonresponders (overall survival, <1 year) was evaluated. Treatment-response-assessment maps (TRAMs) were calculated by subtracting conventional T1WI (acquired a few minutes postcontrast) from delayed T1WI (acquired with a delay of >1 hour postcontrast). These maps depict the spatial distribution of contrast accumulation and clearance. At progression, the increase in lesion volumes in delayed-contrast MR imaging was 37.5% higher than the increase in conventional T1WI. The authors conclude that the benefit of standard and delayed-contrast MRI for assessing and predicting the response to bevacizumab was demonstrated and that the increased sensitivity of delayed-contrast MRI reflects its potential contribution to the management of bevacizumab-treated patients with recurrent HGG.

  2. Boiten, J.

    1. EDITOR'S CHOICEADULT BRAIN
      Comparison of CTA- and DSA-Based Collateral Flow Assessment in Patients with Anterior Circulation Stroke
      I.G.H. Jansen, O.A. Berkhemer, A.J. Yoo, J.A. Vos, G.J. Lycklama à Nijeholt, M.E.S. Sprengers, W.H. van Zwam, W.J. Schonewille, J. Boiten, M.A.A. van Walderveen, R.J. van Oostenbrugge, A. van der Lugt, H.A. Marquering and C.B.L.M. Majoie on behalf of the MR CLEAN investigators (www.mrclean-trial.org)
      American Journal of Neuroradiology November 2016, 37 (11) 2037-2042; DOI: https://doi.org/10.3174/ajnr.A4878

      The authors set out to determine the agreement between collateral flow assessment on CTA and DSA and their respective associations with clinical outcome. They used patient data that was randomized in MR CLEAN with middle cerebral artery occlusion and both baseline CTA images and complete DSA runs. Collateral flow on CTA and DSA was graded 0 (absent) to 3 (good).Of 45 patients with evaluable imaging data, collateral flow was graded on CTA as 0, 1, 2, 3 for 3, 10, 20, and 12 patients, respectively, and on DSA for 12, 17, 10, and 6 patients, respectively. The adjusted odds ratio for favorable outcome on mRS was 2.27 and 1.29 for CTA and DSA, respectively. The relationship between the dichotomized collateral score and mRS 0–2 was significant for CTA, but not for DSA. They conclude that the commonly applied collateral flow assessment on CTA and DSA showed large differences and that these techniques are not interchangeable. CTA was significantly associated with mRS at 90 days, whereas DSA was not.

  3. Bokstein, F.

    1. EDITOR'S CHOICEADULT BRAIN
      Early Biomarkers from Conventional and Delayed-Contrast MRI to Predict the Response to Bevacizumab in Recurrent High-Grade Gliomas
      D. Daniels, D. Guez, D. Last, C. Hoffmann, D. Nass, A. Talianski, G. Tsarfaty, S. Salomon, A.A. Kanner, D.T. Blumenthal, F. Bokstein, S. Harnof, D. Yekutieli, S. Zamir, Z.R. Cohen, L. Zach and Y. Mardor
      American Journal of Neuroradiology November 2016, 37 (11) 2003-2009; DOI: https://doi.org/10.3174/ajnr.A4866

      Twenty-four patients with recurrent high-grade gliomas were scanned before and during bevacizumab treatment with standard and delayed-contrast MRI. The mean change in lesion volumes of responders (overall survival, >1 year) and nonresponders (overall survival, <1 year) was evaluated. Treatment-response-assessment maps (TRAMs) were calculated by subtracting conventional T1WI (acquired a few minutes postcontrast) from delayed T1WI (acquired with a delay of >1 hour postcontrast). These maps depict the spatial distribution of contrast accumulation and clearance. At progression, the increase in lesion volumes in delayed-contrast MR imaging was 37.5% higher than the increase in conventional T1WI. The authors conclude that the benefit of standard and delayed-contrast MRI for assessing and predicting the response to bevacizumab was demonstrated and that the increased sensitivity of delayed-contrast MRI reflects its potential contribution to the management of bevacizumab-treated patients with recurrent HGG.

  4. Boll, M.-C.

    1. ADULT BRAIN
      Open Access
      Ataxia Severity Correlates with White Matter Degeneration in Spinocerebellar Ataxia Type 7
      C.R. Hernandez-Castillo, I. Vaca-Palomares, F. Barrios, L. Martinez, M.-C. Boll and J. Fernandez-Ruiz
      American Journal of Neuroradiology November 2016, 37 (11) 2050-2054; DOI: https://doi.org/10.3174/ajnr.A4903

  5. Boothe, E.

    1. PERIPHERAL NERVOUS SYSTEM
      3D MR Neurography of the Lumbosacral Plexus: Obtaining Optimal Images for Selective Longitudinal Nerve Depiction
      G. Cho Sims, E. Boothe, R. Joodi and A. Chhabra
      American Journal of Neuroradiology November 2016, 37 (11) 2158-2162; DOI: https://doi.org/10.3174/ajnr.A4879

  6. Bortolotti, C.

    1. ADULT BRAIN
      Open Access
      Aneurysms Associated with Brain Arteriovenous Malformations
      S.K. Rammos, B. Gardenghi, C. Bortolotti, H.J. Cloft and G. Lanzino
      American Journal of Neuroradiology November 2016, 37 (11) 1966-1971; DOI: https://doi.org/10.3174/ajnr.A4869

  7. Bouillot, P.

    1. INTERVENTIONAL
      Open Access
      Virtual-versus-Real Implantation of Flow Diverters: Clinical Potential and Influence of Vascular Geometry
      P. Bouillot, O. Brina, H. Yilmaz, M. Farhat, G. Erceg, K.-O. Lovblad, M.I. Vargas, Z. Kulcsar and V.M. Pereira
      American Journal of Neuroradiology November 2016, 37 (11) 2079-2086; DOI: https://doi.org/10.3174/ajnr.A4845

  8. Bracco, S.

    1. Reply:
      S. Bracco and E. Bertelli
      American Journal of Neuroradiology November 2016, 37 (11) E73; DOI: https://doi.org/10.3174/ajnr.A4910

  9. Branch, C.A.

    1. ADULT BRAIN
      Open Access
      Bidirectional Changes in Anisotropy Are Associated with Outcomes in Mild Traumatic Brain Injury
      S.B. Strauss, N. Kim, C.A. Branch, M.E. Kahn, M. Kim, R.B. Lipton, J.M. Provataris, H.F. Scholl, M.E. Zimmerman and M.L. Lipton
      American Journal of Neuroradiology November 2016, 37 (11) 1983-1991; DOI: https://doi.org/10.3174/ajnr.A4851

  10. Brina, O.

    1. INTERVENTIONAL
      Open Access
      Virtual-versus-Real Implantation of Flow Diverters: Clinical Potential and Influence of Vascular Geometry
      P. Bouillot, O. Brina, H. Yilmaz, M. Farhat, G. Erceg, K.-O. Lovblad, M.I. Vargas, Z. Kulcsar and V.M. Pereira
      American Journal of Neuroradiology November 2016, 37 (11) 2079-2086; DOI: https://doi.org/10.3174/ajnr.A4845
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