Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • AJNR Case Collection
    • Case of the Week Archive
    • Classic Case Archive
    • Case of the Month Archive
  • Special Collections
    • Spinal CSF Leak Articles (Jan 2020-June 2024)
    • 2024 AJNR Journal Awards
    • Most Impactful AJNR Articles
  • Multimedia
    • AJNR Podcast
    • AJNR Scantastics
    • Video Articles
  • For Authors
    • Submit a Manuscript
    • Author Policies
    • Fast publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Manuscript Submission Guidelines
    • Imaging Protocol Submission
    • Submit a Case for the Case Collection
  • About Us
    • About AJNR
    • Editorial Board
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Other Publications
    • ajnr

User menu

  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

ASHNR American Society of Functional Neuroradiology ASHNR American Society of Pediatric Neuroradiology ASSR
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • AJNR Case Collection
    • Case of the Week Archive
    • Classic Case Archive
    • Case of the Month Archive
  • Special Collections
    • Spinal CSF Leak Articles (Jan 2020-June 2024)
    • 2024 AJNR Journal Awards
    • Most Impactful AJNR Articles
  • Multimedia
    • AJNR Podcast
    • AJNR Scantastics
    • Video Articles
  • For Authors
    • Submit a Manuscript
    • Author Policies
    • Fast publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Manuscript Submission Guidelines
    • Imaging Protocol Submission
    • Submit a Case for the Case Collection
  • About Us
    • About AJNR
    • Editorial Board
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds

Welcome to the new AJNR, Updated Hall of Fame, and more. Read the full announcements.


AJNR is seeking candidates for the position of Associate Section Editor, AJNR Case Collection. Read the full announcement.

 

Research ArticleAdult Brain

CT Perfusion in Acute Lacunar Stroke: Detection Capabilities Based on Infarct Location

J.C. Benson, S. Payabvash, S. Mortazavi, L. Zhang, P. Salazar, B. Hoffman, M. Oswood and A.M. McKinney
American Journal of Neuroradiology December 2016, 37 (12) 2239-2244; DOI: https://doi.org/10.3174/ajnr.A4904
J.C. Benson
aFrom the Department of Radiology (J.C.B., S.P., S.M., A.M.M.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for J.C. Benson
S. Payabvash
aFrom the Department of Radiology (J.C.B., S.P., S.M., A.M.M.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for S. Payabvash
S. Mortazavi
aFrom the Department of Radiology (J.C.B., S.P., S.M., A.M.M.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for S. Mortazavi
L. Zhang
bClinical and Translational Science Institute (L.Z., P.S.), University of Minnesota Medical Center, Minneapolis, Minnesota
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for L. Zhang
P. Salazar
bClinical and Translational Science Institute (L.Z., P.S.), University of Minnesota Medical Center, Minneapolis, Minnesota
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for P. Salazar
B. Hoffman
cVital Images, a division of Toshiba Medical (B.H., M.O.), Minnetonka, Minnesota
dDepartment of Radiology (B.H., M.O.), Hennepin County Medical Center, Minneapolis, Minnesota.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for B. Hoffman
M. Oswood
cVital Images, a division of Toshiba Medical (B.H., M.O.), Minnetonka, Minnesota
dDepartment of Radiology (B.H., M.O.), Hennepin County Medical Center, Minneapolis, Minnesota.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for M. Oswood
A.M. McKinney
aFrom the Department of Radiology (J.C.B., S.P., S.M., A.M.M.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for A.M. McKinney
  • Article
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF
Loading

References

  1. 1.↵
    1. Micheli S,
    2. Corea F
    . Lacunar versus non-lacunar syndromes. Front Neurol Neurosci 2012;30:94–98 doi:10.1159/000333426 pmid:22377873
    CrossRefPubMed
  2. 2.↵
    1. Altmann M,
    2. Thommessen B,
    3. Rønning OM, et al
    . Diagnostic accuracy and risk factors of the different lacunar syndromes. J Stroke Cerebrovasc Dis 2014;23:2085–90 doi:10.1016/j.jstrokecerebrovasdis.2014.03.014 pmid:25126698
    CrossRefPubMed
  3. 3.↵
    1. Hommel M,
    2. Besson G,
    3. Le Bas JF, et al
    . Prospective study of lacunar infarction using magnetic resonance imaging. Stroke 1990;21:546–54 doi:10.1161/01.STR.21.4.546 pmid:2326835
    Abstract/FREE Full Text
  4. 4.↵
    1. Das T,
    2. Settecase F,
    3. Boulos M, et al
    . Multimodal CT provides improved performance for lacunar infarct detection. AJNR Am J Neuroradiol 2015;36:1069–75 doi:10.3174/ajnr.A4255 pmid:25721075
    Abstract/FREE Full Text
  5. 5.↵
    1. Caso V,
    2. Budak K,
    3. Georgiadis D, et al
    . Clinical significance of detection of multiple acute brain infarcts on diffusion weighted magnetic resonance imaging. J Neurol Neurosurg Psychiatry 2005;76:514–18 doi:10.1136/jnnp.2004.046383 pmid:15774438
    Abstract/FREE Full Text
  6. 6.↵
    1. Norrving B
    . Long-term prognosis after lacunar infarction. Lancet Neurol 2003;2:238–45 doi:10.1016/S1474-4422(03)00352-1 pmid:12849212
    CrossRefPubMedWeb of Science
  7. 7.↵
    1. Norrving B
    . Evolving concept of small vessel disease through advanced brain imaging. J Stroke 2015;17:94–100 doi:10.5853/jos.2015.17.2.94 pmid:26060796
    CrossRefPubMed
  8. 8.↵
    1. Arboix A,
    2. Martí-Vilalta JL
    . Lacunar stroke. Expert Rev Neurother 2009;9:179–96 doi:10.1586/14737175.9.2.179 pmid:19210194
    CrossRefPubMed
  9. 9.↵
    1. Pantoni L,
    2. Fierini F,
    3. Poggesi A
    . Thrombolysis in acute stroke patients with cerebral small vessel disease. Cerebrovasc Dis 2014;37:5–13 doi:10.1159/000356796 pmid:24355873
    CrossRefPubMed
  10. 10.↵
    1. Hana T,
    2. Iwama J,
    3. Yokosako S, et al
    . Sensitivity of CT perfusion for the diagnosis of cerebral infarction. J Med Invest 2014;61:41–45 doi:10.2152/jmi.61.41 pmid:24705747
    CrossRefPubMed
  11. 11.↵
    1. Chamorro A,
    2. Sacco RL,
    3. Mohr JP, et al
    . Clinical-computed tomographic correlations of lacunar infarction in the Stroke Data Bank. Stroke 1991;22:175–81 doi:10.1161/01.STR.22.2.175 pmid:2003281
    Abstract/FREE Full Text
  12. 12.↵
    1. Smajlović D,
    2. Sinanović O
    . Sensitivity of the neuroimaging techniques in ischemic stroke. Med Arh 2004;58:282–84 pmid:15628251
    PubMed
  13. 13.↵
    1. Lai PH,
    2. Li JY,
    3. Chang CY, et al
    . Sensitivity of diffusion-weighted magnetic resonance imaging in the diagnosis of acute lacunar infarcts. J Formos Med Assoc 2001;100:370–76 pmid:11480245
    PubMedWeb of Science
  14. 14.↵
    1. Wintermark M,
    2. Bogousslavsky J
    . Imaging of acute ischemic brain injury: the return of computed tomography. Curr Opin Neurol 2003;16:59–63 doi:10.1097/00019052-200302000-00008 pmid:12544858
    CrossRefPubMedWeb of Science
  15. 15.↵
    1. Rudilosso S,
    2. Urra X,
    3. San Román L, et al
    . Perfusion deficits and mismatch in patients with acute lacunar infarcts studied with whole-brain CT perfusion. AJNR Am J Neuroradiol 2015;36:1407–12 doi:10.3174/ajnr.A4303 pmid:25882287
    Abstract/FREE Full Text
  16. 16.↵
    1. Potter GM,
    2. Marlborough FJ,
    3. Wardlaw JM
    . Wide variation in definition, detection, and description of lacunar lesions on imaging. Stroke 2011;42:359–66 doi:10.1161/STROKEAHA.110.594754 pmid:21193752
    Abstract/FREE Full Text
  17. 17.↵
    1. Leiva-Salinas C,
    2. Provenzale JM,
    3. Wintermark M
    . Responses to the 10 most frequently asked questions about perfusion CT. AJR Am J Roentgenol 2011;196:53–60 doi:10.2214/AJR.10.5705 pmid:21178046
    CrossRefPubMed
  18. 18.↵
    1. Tomandl BF,
    2. Klotz E,
    3. Handschu R, et al
    . Comprehensive imaging of ischemic stroke with multisection CT. Radiographics 2003;23:565–92 doi:10.1148/rg.233025036 pmid:12740462
    CrossRefPubMedWeb of Science
  19. 19.↵
    1. Longstreth WT Jr.,
    2. Bernick C,
    3. Manolio TA, et al
    . Lacunar infarcts defined by magnetic resonance imaging of 3660 elderly people: the Cardiovascular Health Study. Arch Neurol 1998;55:1217–25 doi:10.1001/archneur.55.9.1217 pmid:9740116
    CrossRefPubMedWeb of Science
  20. 20.↵
    1. Mayer TE,
    2. Hamann GF,
    3. Baranczyk J, et al
    . Dynamic CT perfusion imaging of acute stroke. AJNR Am J Neuroradiol 2000;21:1441–49 pmid:11003276
    Abstract/FREE Full Text
  21. 21.↵
    1. Maruya J,
    2. Yamamoto K,
    3. Ozawa T, et al
    . Simultaneous multi-section perfusion CT and CT angiography for the assessment of acute ischemic stroke. Acta Neurochir (Wien) 2005;147:383–91; discussion 391–92 doi:10.1007/s00701-004-0465-3 pmid:15662567
    CrossRefPubMed
  22. 22.↵
    1. Biesbroek JM,
    2. Niesten JM,
    3. Dankbaar JW, et al
    . Diagnostic accuracy of CT perfusion imaging for detecting acute ischemic stroke: a systematic review and meta-analysis. Cerebrovasc Dis 2013;35:493–501 doi:10.1159/000350200 pmid:23736122
    CrossRefPubMed
  23. 23.↵
    1. Eckert B,
    2. Küsel T,
    3. Leppien A, et al
    . Clinical outcome and imaging follow-up in acute stroke patients with normal perfusion CT and normal CT angiography. Neuroradiology 2011;53:79–88 doi:10.1007/s00234-010-0702-9 pmid:20422406
    CrossRefPubMed
  24. 24.↵
    1. Sasaki M,
    2. Kudo K,
    3. Ogasawara K, et al
    . Tracer delay-insensitive algorithm can improve reliability of CT perfusion imaging for cerebrovascular steno-occlusive disease: comparison with quantitative single-photon emission CT. AJNR Am J Neuroradiol 2009;30:188–93 doi:10.3174/ajnr.A1274 pmid:18768719
    Abstract/FREE Full Text
  25. 25.↵
    1. Kudo K,
    2. Sasaki M,
    3. Ogasawara K, et al
    . Difference in tracer delay-induced effect among deconvolution algorithms in CT perfusion analysis: quantitative evaluation with digital phantoms. Radiology 2009;251:241–49 doi:10.1148/radiol.2511080983 pmid:19190251
    CrossRefPubMedWeb of Science
  26. 26.↵
    1. Cao W,
    2. Yassi N,
    3. Sharma G, et al
    . Diagnosing acute lacunar infarction using CT perfusion. J Clin Neurosci 2016;29:70–72 doi:10.1016/j.jocn.2016.01.001 pmid:26899357
    CrossRefPubMed
PreviousNext
Back to top

In this issue

American Journal of Neuroradiology: 37 (12)
American Journal of Neuroradiology
Vol. 37, Issue 12
1 Dec 2016
  • Table of Contents
  • Index by author
  • Complete Issue (PDF)
Advertisement
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
CT Perfusion in Acute Lacunar Stroke: Detection Capabilities Based on Infarct Location
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Cite this article
J.C. Benson, S. Payabvash, S. Mortazavi, L. Zhang, P. Salazar, B. Hoffman, M. Oswood, A.M. McKinney
CT Perfusion in Acute Lacunar Stroke: Detection Capabilities Based on Infarct Location
American Journal of Neuroradiology Dec 2016, 37 (12) 2239-2244; DOI: 10.3174/ajnr.A4904

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
0 Responses
Respond to this article
Share
Bookmark this article
CT Perfusion in Acute Lacunar Stroke: Detection Capabilities Based on Infarct Location
J.C. Benson, S. Payabvash, S. Mortazavi, L. Zhang, P. Salazar, B. Hoffman, M. Oswood, A.M. McKinney
American Journal of Neuroradiology Dec 2016, 37 (12) 2239-2244; DOI: 10.3174/ajnr.A4904
del.icio.us logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Purchase

Jump to section

  • Article
    • Abstract
    • ABBREVIATIONS:
    • Materials and Methods
    • Results
    • Discussion
    • Conclusions
    • Footnotes
    • References
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • Falsely normal CT perfusion ischemic core readings are common and often associated with deep infarcts
  • Impact Analysis of Different CT Configurations of Carotid Artery Plaque Calcifications on Cerebrovascular Events
  • Acute Ischemic Stroke or Epileptic Seizure? Yield of CT Perfusion in a "Code Stroke" Situation
  • Automated CT perfusion imaging for acute ischemic stroke: Pearls and pitfalls for real-world use
  • Crossref (39)
  • Google Scholar

This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

  • Review of Perfusion Imaging in Acute Ischemic Stroke
    Jelle Demeestere, Anke Wouters, Soren Christensen, Robin Lemmens, Maarten G. Lansberg
    Stroke 2020 51 3
  • Automated CT perfusion imaging for acute ischemic stroke
    Achala Vagal, Max Wintermark, Kambiz Nael, Andrew Bivard, Mark Parsons, Aaron W. Grossman, Pooja Khatri
    Neurology 2019 93 20
  • The Potential Impact of Neuroimaging and Translational Research on the Clinical Management of Lacunar Stroke
    Salvatore Rudilosso, Alejandro Rodríguez-Vázquez, Xabier Urra, Adrià Arboix
    International Journal of Molecular Sciences 2022 23 3
  • Ischemic Volume and Neurological Deficit: Correlation of Computed Tomography Perfusion with the National Institutes of Health Stroke Scale Score in Acute Ischemic Stroke
    Giovanni Furlanis, Miloš Ajčević, Lara Stragapede, Carlo Lugnan, Mariana Ridolfi, Paola Caruso, Marcello Naccarato, Maja Ukmar, Paolo Manganotti
    Journal of Stroke and Cerebrovascular Diseases 2018 27 8
  • Self-Supervised Dynamic CT Perfusion Image Denoising With Deep Neural Networks
    Dufan Wu, Hui Ren, Quanzheng Li
    IEEE Transactions on Radiation and Plasma Medical Sciences 2021 5 3
  • Wake-up stroke and CT perfusion: effectiveness and safety of reperfusion therapy
    Paola Caruso, Marcello Naccarato, Giovanni Furlanis, Miloš Ajčević, Lara Stragapede, Mariana Ridolfi, Paola Polverino, Maja Ukmar, Paolo Manganotti
    Neurological Sciences 2018 39 10
  • Impact Analysis of Different CT Configurations of Carotid Artery Plaque Calcifications on Cerebrovascular Events
    L. Saba, H. Chen, R. Cau, G.D. Rubeis, G. Zhu, F. Pisu, B. Jang, G. Lanzino, J.S. Suri, Y. Qi, M. Wintermark
    American Journal of Neuroradiology 2022 43 2
  • Automated Brain Perfusion Imaging in Acute Ischemic Stroke: Interpretation Pearls and Pitfalls
    Manal Nicolas-Jilwan, Max Wintermark
    Stroke 2021 52 11
  • Cerebral perfusion and compensatory blood supply in patients with recent small subcortical infarcts
    Salvatore Rudilosso, Carlos Laredo, Marco Mancosu, Nuria Moya-Planas, Yashu Zhao, Oscar Chirife, Ángel Chamorro, Xabier Urra
    Journal of Cerebral Blood Flow & Metabolism 2019 39 7
  • Automated Processing of Head CT Perfusion Imaging for Ischemic Stroke Triage: A Practical Guide to Quality Assurance and Interpretation
    Charlotte Y. Chung, Ranliang Hu, Ryan B. Peterson, Jason W. Allen
    American Journal of Roentgenology 2021 217 6

More in this TOC Section

  • Diagnostic Neuroradiology of Monoclonal Antibodies
  • ML for Glioma Molecular Subtype Prediction
  • Segmentation of Brain Metastases with BLAST
Show more Adult Brain

Similar Articles

Advertisement

Indexed Content

  • Current Issue
  • Accepted Manuscripts
  • Article Preview
  • Past Issues
  • Editorials
  • Editors Choice
  • Fellow Journal Club
  • Letters to the Editor

Cases

  • Case Collection
  • Archive - Case of the Week
  • Archive - Case of the Month
  • Archive - Classic Case

Special Collections

  • Special Collections

Resources

  • News and Updates
  • Turn around Times
  • Submit a Manuscript
  • Author Policies
  • Manuscript Submission Guidelines
  • Evidence-Based Medicine Level Guide
  • Publishing Checklists
  • Graphical Abstract Preparation
  • Imaging Protocol Submission
  • Submit a Case
  • Become a Reviewer/Academy of Reviewers
  • Get Peer Review Credit from Publons

Multimedia

  • AJNR Podcast
  • AJNR SCANtastic
  • Video Articles

About Us

  • About AJNR
  • Editorial Board
  • Not an AJNR Subscriber? Join Now
  • Alerts
  • Feedback
  • Advertise with us
  • Librarian Resources
  • Permissions
  • Terms and Conditions

American Society of Neuroradiology

  • Not an ASNR Member? Join Now

© 2025 by the American Society of Neuroradiology All rights, including for text and data mining, AI training, and similar technologies, are reserved.
Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire