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Research ArticleNeurointervention

Safety and Efficacy of Intravenous Tirofiban as Antiplatelet Premedication for Stent-Assisted Coiling in Acutely Ruptured Intracranial Aneurysms

S. Kim, J.-H. Choi, M. Kang, J.-K. Cha and J.-T. Huh
American Journal of Neuroradiology March 2016, 37 (3) 508-514; DOI: https://doi.org/10.3174/ajnr.A4551
S. Kim
aFrom the Departments of Radiology (S.K., M.K.)
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J.-H. Choi
bNeurosurgery (J.-H.C., J.-T.H.)
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M. Kang
aFrom the Departments of Radiology (S.K., M.K.)
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J.-K. Cha
cNeurology (J.-K.C.), Busan-Ulsan Regional Cardio-Cerebrovascular Disease Center, Dong-A University Hospital, Busan, Republic of Korea.
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J.-T. Huh
bNeurosurgery (J.-H.C., J.-T.H.)
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References

  1. 1.↵
    1. Molyneux AJ,
    2. Kerr RS,
    3. Yu LM, et al
    . International subarachnoid aneurysm trial (ISAT) of neurosurgical clipping versus endovascular coiling in 2143 patients with ruptured intracranial aneurysm: a randomised comparison of effects on survival, dependency, seizures, rebleeding, subgroups, and aneurysm occlusion. Lancet 2005;366:809–17 doi:10.1016/S0140-6736(05)67214-5 pmid:16139655
    CrossRefPubMedWeb of Science
  2. 2.↵
    1. Benitez RP,
    2. Silva MT,
    3. Klem J, et al
    . Endovascular occlusion of wide-necked aneurysms with a new intracranial microstent (Neuroform) and detachable coils. Neurosurgery 2004;54:1359–67; discussion 1368 doi:10.1227/01.NEU.0000124484.87635.CD pmid:15157292
    CrossRefPubMedWeb of Science
  3. 3.↵
    1. Fiorella D,
    2. Albuquerque FC,
    3. Han P, et al
    . Preliminary experience using the Neuroform stent for the treatment of cerebral aneurysms. Neurosurgery 2004;54:6–16; discussion 16–17 doi:10.1227/01.NEU.0000097194.35781.EA pmid:14683536
    CrossRefPubMedWeb of Science
  4. 4.↵
    1. Piotin M,
    2. Blanc R,
    3. Spelle L, et al
    . Stent-assisted coiling of intracranial aneurysms: clinical and angiographic results in 216 consecutive aneurysms. Stroke 2010;41:110–15 doi:10.1161/STROKEAHA.109.558114 pmid:19959540
    CrossRefPubMed
  5. 5.↵
    1. Jeong HW,
    2. Jin SC
    . Intra-arterial infusion of a glycoprotein IIb/IIIa antagonist for the treatment of thromboembolism during coil embolization of intracranial aneurysm: a comparison of abciximab and tirofiban. AJNR Am J Neuroradiol 2013;34:1621–25 doi:10.3174/ajnr.A3501 pmid:23660289
    Abstract/FREE Full Text
  6. 6.↵
    1. Aggour M,
    2. Pierot L,
    3. Kadziolka K, et al
    . Abciximab treatment modalities for thromboembolic events related to aneurysm coiling. Neurosurgery 2010;67(2 suppl operative):503–08 doi:10.1227/NEU.0b013e3181f8d1db pmid:21099579
    CrossRefPubMed
  7. 7.↵
    1. Yi HJ,
    2. Gupta R,
    3. Jovin TG, et al
    . Initial experience with the use of intravenous eptifibatide bolus during endovascular treatment of intracranial aneurysms. AJNR Am J Neuroradiol 2006;27:1856–60 pmid:17032856
    Abstract/FREE Full Text
  8. 8.↵
    1. Dawson P,
    2. Strickland NH
    . Thromboembolic phenomena in clinical angiography; role of materials and technique. J Vasc Interv Radiol 1991;2:125–32 doi:10.1016/S1051-0443(91)72485-88 pmid:1799742
    CrossRefPubMed
  9. 9.↵
    1. Pierot L,
    2. Spelle L,
    3. Vitry F
    . Immediate clinical outcome of patients harboring unruptured intracranial aneurysms treated by endovascular approach: results of the ATENA study. Stroke 2008;39:2497–504 doi:10.1161/STROKEAHA.107.512756 pmid:18617659
    Abstract/FREE Full Text
  10. 10.↵
    1. Bodily KD,
    2. Cloft HJ,
    3. Lanzino G, et al
    . Stent-assisted coiling in acutely ruptured intracranial aneurysms: a qualitative, systematic review of the literature. AJNR Am J Neuroradiol 2011;32:1232–36 doi:10.3174/ajnr.A2478 pmid:21546464
    Abstract/FREE Full Text
  11. 11.↵
    1. Meckel S,
    2. Singh TP,
    3. Undrén P, et al
    . Endovascular treatment using predominantly stent-assisted coil embolization and antiplatelet and anticoagulation management of ruptured blood blister-like aneurysms. AJNR Am J Neuroradiol 2011;32:764–71 doi:10.3174/ajnr.A2392 pmid:21372169
    Abstract/FREE Full Text
  12. 12.↵
    1. Ries T,
    2. Buhk JH,
    3. Kucinski T, et al
    . Intravenous administration of acetylsalicylic acid during endovascular treatment of cerebral aneurysms reduces the rate of thromboembolic events. Stroke 2006;37:1816–21 doi:10.1161/01.STR.0000226933.44962.a6 pmid:16778126
    Abstract/FREE Full Text
  13. 13.↵
    1. Müller I,
    2. Seyfarth M,
    3. Rüdiger S, et al
    . Effect of a high loading dose of clopidogrel on platelet function in patients undergoing coronary stent placement. Heart 2001;85:92–93 doi:10.1136/heart.85.1.92 pmid:11119474
    FREE Full Text
  14. 14.↵
    1. Park JH,
    2. Kim JE,
    3. Sheen SH, et al
    . Intraarterial abciximab for treatment of thromboembolism during coil embolization of intracranial aneurysms: outcome and fatal hemorrhagic complications. J Neurosurg 2008;108:450–57 doi:10.3171/JNS/2008/108/3/0450 pmid:18312090
    CrossRefPubMedWeb of Science
  15. 15.↵
    1. Walsh RD,
    2. Barrett KM,
    3. Aguilar MI, et al
    . Intracranial hemorrhage following neuroendovascular procedures with abciximab is associated with high mortality: a multicenter series. Neurocrit Care 2011;15:85–95 doi:10.1007/s12028-010-9338-1 pmid:20169473
    CrossRefPubMedWeb of Science
  16. 16.↵
    1. Cho YD,
    2. Lee JY,
    3. Seo JH, et al
    . Early recurrent hemorrhage after coil embolization in ruptured intracranial aneurysms. Neuroradiology 2012;54:719–26 doi:10.1007/s00234-011-0950-3 pmid:21969241
    CrossRefPubMedWeb of Science
  17. 17.↵
    1. Tcheng JE,
    2. Ellis SG,
    3. George BS, et al
    . Pharmacodynamics of chimeric glycoprotein IIb/IIIa integrin antiplatelet antibody Fab 7E3 in high-risk coronary angioplasty. Circulation 1994;90:1757–64 doi:10.1161/01.CIR.90.4.1757 pmid:7923659
    Abstract/FREE Full Text
  18. 18.↵
    1. McCuigan MA,
    2. Caravati EM
    1. Dart RC
    ed, McCuigan MA, Caravati EM. Medical Toxicology. 3rd ed. Philadelphia: Lippincott, Williams & Wilkins; 2003:635–37
  19. 19.↵
    Highlights of prescribing information: AGGRASTAT (tirofiban hydrochloride). Food and Drug Administration, Silver Spring, Maryland. http://www.accessdata.fda.gov/drugsatfda_docs/label/2013/020912s019s020lbl.pdf. Accessed August 7, 2015.
  20. 20.↵
    1. Chalouhi N,
    2. Jabbour P,
    3. Kung D, et al
    . Safety and efficacy of tirofiban in stent-assisted coil embolization of intracranial aneurysms. Neurosurgery 2012;71:710–14; discussion 714 doi:10.1227/NEU.0b013e31826213f9 pmid:22668886
    CrossRefPubMed
  21. 21.↵
    1. Lodi YM,
    2. Latorre JG,
    3. El-Zammar Z, et al
    . Stent assisted coiling of the ruptured wide necked intracranial aneurysm. J Neurointerv Surg 2012;4:281–86 doi:10.1136/neurintsurg-2011-010035 pmid:21990500
    Abstract/FREE Full Text
  22. 22.↵
    1. Roitberg BZ,
    2. Khan N,
    3. Alp MS, et al
    . Bedside external ventricular drain placement for the treatment of acute hydrocephalus. Br J Neurosurg 2001;15:324–27 doi:10.1080/02688690120072478 pmid:11599448
    CrossRefPubMed
  23. 23.↵
    1. Ehtisham A,
    2. Taylor S,
    3. Bayless L, et al
    . Placement of external ventricular drains and intracranial pressure monitors by neurointensivists. Neurocrit Care 2009;10:241–47 doi:10.1007/s12028-008-9097-4 pmid:18449808
    CrossRefPubMedWeb of Science
  24. 24.↵
    1. Binz DD,
    2. Toussaint LG 3rd.,
    3. Friedman JA
    . Hemorrhagic complications of ventriculostomy placement: a meta-analysis. Neurocrit Care 2009;10:253–56 doi:10.1007/s12028-009-9193-0 pmid:19224404
    CrossRefPubMedWeb of Science
  25. 25.↵
    1. Scholz C,
    2. Hubbe U,
    3. Deininger M, et al
    . Hemorrhage rates of external ventricular drain (EVD), intracranial pressure gauge (ICP) or combined EVD and ICP gauge placement within 48 h of endovascular coil embolization of cerebral aneurysms. Clin Neurol Neurosurg 2013;115:1399–402 doi:10.1016/j.clineuro.2013.01.023 pmid:23428140
    CrossRefPubMed
  26. 26.↵
    1. Kung DK,
    2. Policeni BA,
    3. Capuano AW, et al
    . Risk of ventriculostomy-related hemorrhage in patients with acutely ruptured aneurysms treated using stent-assisted coiling. J Neurosurg 2011;114:1021–27 doi:10.3171/2010.9.JNS10445 pmid:20950080
    CrossRefPubMedWeb of Science
  27. 27.↵
    1. Wiviott SD,
    2. Braunwald E,
    3. McCabe CH, et al
    ; TRITON-TIMI 38 Investigators. Prasugrel versus clopidogrel in patients with acute coronary syndromes. N Engl J Med 2007;357:2001–15 doi:10.1056/NEJMoa0706482 pmid:17982182
    CrossRefPubMedWeb of Science
  28. 28.↵
    1. Gurbel PA,
    2. Bliden KP,
    3. Butler K, et al
    . Randomized double-blind assessment of the ONSET and OFFSET of the antiplatelet effects of ticagrelor versus clopidogrel in patients with stable coronary artery disease: the ONSET/OFFSET study. Circulation 2009;120:2577–85 doi:10.1161/CIRCULATIONAHA.109.912550 pmid:19923168
    Abstract/FREE Full Text
  29. 29.↵
    1. Zhu B,
    2. Effron MB,
    3. Kulkarni MP, et al
    . The onset of inhibition of platelet aggregation with prasugrel compared with clopidogrel loading doses using gatekeeping analysis of integrated clinical pharmacology data. J Cardiovasc Pharmacol 2011;57:317–24 doi:10.1097/FJC.0b013e3182073dfb pmid:21266916
    CrossRefPubMed
  30. 30.↵
    1. Kulcsár Z,
    2. Wetzel SG,
    3. Augsburger L, et al
    . Effect of flow diversion treatment on very small ruptured aneurysms. Neurosurgery 2010;67:789–93 doi:10.1227/01.NEU.0000372920.39101.55 pmid:20657324
    CrossRefPubMedWeb of Science
  31. 31.↵
    1. Aydin K,
    2. Arat A,
    3. Sencer S, et al
    . Treatment of ruptured blood blister-like aneurysms with flow diverter SILK stents. J Neurointerv Surg 2015;7:202–09 doi:10.1136/neurintsurg-2013-011090 pmid:24491271
    Abstract/FREE Full Text
  32. 32.↵
    1. Chalouhi N,
    2. Zanaty M,
    3. Starke R, et al
    . O-022: a new protocol for anticoagulation with tirofiban during stenting of intracranial aneurysms. J Neurointerv Surg 2014;6:A11–12 doi:10.1136/neurintsurg-2014-011343.22
    Abstract/FREE Full Text
  33. 33.↵
    AGGRASTAT (tirofiban hydrochloride). MERCK & CO., INC., West Point, PA. Food and Drug Administration, Silver Spring, Maryland. http://www.accessdata.fda.gov/drugsatfda_docs/label/1998/20913lbl.pdf. Accessed August 8, 2015.
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S. Kim, J.-H. Choi, M. Kang, J.-K. Cha, J.-T. Huh
Safety and Efficacy of Intravenous Tirofiban as Antiplatelet Premedication for Stent-Assisted Coiling in Acutely Ruptured Intracranial Aneurysms
American Journal of Neuroradiology Mar 2016, 37 (3) 508-514; DOI: 10.3174/ajnr.A4551

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Safety and Efficacy of Intravenous Tirofiban as Antiplatelet Premedication for Stent-Assisted Coiling in Acutely Ruptured Intracranial Aneurysms
S. Kim, J.-H. Choi, M. Kang, J.-K. Cha, J.-T. Huh
American Journal of Neuroradiology Mar 2016, 37 (3) 508-514; DOI: 10.3174/ajnr.A4551
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  • The Prophylactic Use of Tirofiban versus Oral Antiplatelet Medications in Stent-Assisted Coiling of Intracranial Aneurysms: A Meta-analysis
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