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Research ArticleNeurointervention

Mechanical Thrombectomy of Distal Occlusions in the Anterior Cerebral Artery: Recanalization Rates, Periprocedural Complications, and Clinical Outcome

J. Pfaff, C. Herweh, M. Pham, S. Schieber, P.A. Ringleb, M. Bendszus and M. Möhlenbruch
American Journal of Neuroradiology April 2016, 37 (4) 673-678; DOI: https://doi.org/10.3174/ajnr.A4594
J. Pfaff
aFrom the Departments of Neuroradiology (J.P., C.H., M.P., M.B., M.M.)
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  • ORCID record for J. Pfaff
C. Herweh
aFrom the Departments of Neuroradiology (J.P., C.H., M.P., M.B., M.M.)
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  • ORCID record for C. Herweh
M. Pham
aFrom the Departments of Neuroradiology (J.P., C.H., M.P., M.B., M.M.)
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S. Schieber
bNeurology (S.S., P.A.R.), University of Heidelberg, Heidelberg, Germany.
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P.A. Ringleb
bNeurology (S.S., P.A.R.), University of Heidelberg, Heidelberg, Germany.
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M. Bendszus
aFrom the Departments of Neuroradiology (J.P., C.H., M.P., M.B., M.M.)
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M. Möhlenbruch
aFrom the Departments of Neuroradiology (J.P., C.H., M.P., M.B., M.M.)
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    Figure

    Flowchart of treatments of distal ACA occlusions. The asterisk indicates the percentage of the overall successful stent-retriever placements.

Tables

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    Table 1:

    Baseline characteristics of patients with a distal anterior cerebral artery occlusion

    CharacteristicsPatients (N = 30)
    Age (yr), mean (SD)64 (13)
    Male14 (46.6%)
    Hypertension20 (66.6%)
    Diabetes mellitus5 (16.6%)
    Atrial fibrillation13 (43.3%)
    Coronary artery disease3 (10%)
    Congestive heart failure2 (6.6%)
    Hypercholesterolemia8 (26.6%)
    Previous stroke0 (0%)
    History of smoking3 (10%)
    Prestroke mRS
        022 (73.3%)
        15 (16.6%)
        23 (10%)
    Initial NIHSS score, median (IQR)18 (13–23)
    Time from stroke onset to initial imaging (min), median (IQR)90 (61–155)
        CT16
        MR14
    Time from stroke onset to imaginga (min), median (IQR)
        CT76 (55–150)
        MR154 (87–230)
    ASPECTSa, median (IQR)
        CT9 (9)
        MR7 (7–9)b
    Initial occlusion site
        ICA (excluding Carotid-T)1 (3.3%)
        Carotid-T18 (60%)
        M19 (30%)
        M22 (6.6%)
    Intravenous tPA25 (83.3%)
    Time from stroke onset to groin puncture (min), median (IQR)211 (139–289)
    • Note:—IQR indicates interquartile range.

    • ↵a According to the imaging modality.

    • ↵b MR-ASPECTS was assessed on axial diffusion-weighted images.

    • View popup
    Table 2:

    Occlusion site and vessel diameter of the anterior cerebral artery

    Occlusion SiteTotal (N = 30)Vessel Diameter (mm), mean (SD)No. of Device Passesa, mean (SD)
    Proximal pericallosal artery = A2 segment (between AcomA and genu of corpus callosum)7 (23.3%)1.9 (0.4)1.28 (0.69)
    Middle pericallosal artery = A3 segment (curving around genu of corpus callosum)
        Inferior segment6 (20%)1.8 (0.2)2 (1.26)
        Anterior segment2 (6.6%)2.1 (0.3)1.5 (0.5)
        Superior segment8 (26.6%)1.7 (0.4)1.57 (0.72)
    Distal pericallosal artery
        A4 and A5 segments and distal branches other than CMA5 (16.6%)1.7 (0.4)1 (0)
        CMA2 (6.6%)1.5 (0.1)1 (0)
    • Note:—AcomA indicates anterior communicating artery; CMA, callosomarginal artery.

    • ↵a In patients in whom placement of a stent retriever was possible.

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    Table 3:

    List of types, manufacturers, and number of passes of devices used for mechanical thrombectomy

    DeviceManufacturerSize (mm)No. of Patients TreatedTotal No. of Passes
    AperioaAcandis4.5 × 3013
    CaptureaMindFrameb4.0 × 2012
    Catch MiniaBaltc3 × 1534
    ERICaMicroVention4 × 2411
    RevivedCodman4.5 × 2269
    Solitaire FRdCovidien4 × 201217
    Trevo ProVuedStrykere4 × 2012
    • ↵a Devices fitting through .017-inch microcatheters (eg, Headway 17; MicroVention).

    • ↵b Irvine, California.

    • ↵c Montmorency, France.

    • ↵d Devices fitting through .021-inch microcatheters (eg, Rebar 18; Covidien), and .027-inch microcatheters (Revive, Codman Neurovascular; Rebar 27, Covidien).

    • ↵e Kalamazoo, Michigan.

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American Journal of Neuroradiology: 37 (4)
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J. Pfaff, C. Herweh, M. Pham, S. Schieber, P.A. Ringleb, M. Bendszus, M. Möhlenbruch
Mechanical Thrombectomy of Distal Occlusions in the Anterior Cerebral Artery: Recanalization Rates, Periprocedural Complications, and Clinical Outcome
American Journal of Neuroradiology Apr 2016, 37 (4) 673-678; DOI: 10.3174/ajnr.A4594

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Mechanical Thrombectomy of Distal Occlusions in the Anterior Cerebral Artery: Recanalization Rates, Periprocedural Complications, and Clinical Outcome
J. Pfaff, C. Herweh, M. Pham, S. Schieber, P.A. Ringleb, M. Bendszus, M. Möhlenbruch
American Journal of Neuroradiology Apr 2016, 37 (4) 673-678; DOI: 10.3174/ajnr.A4594
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  • Endovascular treatment for acute ischaemic stroke due to medium vessel occlusion: data from ANGEL-ACT registry
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