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Research ArticleNeurointervention
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Endovascular Therapy of M2 Occlusion in IMS III: Role of M2 Segment Definition and Location on Clinical and Revascularization Outcomes

T.A. Tomsick, J. Carrozzella, L. Foster, M.D. Hill, R. von Kummer, M. Goyal, A.M. Demchuk, P. Khatri, Y. Palesch, J.P. Broderick, S.D. Yeatts, D.S. Liebeskind and for the IMS III Investigators
American Journal of Neuroradiology January 2017, 38 (1) 84-89; DOI: https://doi.org/10.3174/ajnr.A4979

References

  1. 1.↵
    2. Rahme R,
    3. Yeatts SD,
    4. Abruzzo T, et al
    . Early reperfusion and clinical outcome in patients with M2 occlusion: pooled analysis of the PROACT II, IMS, and IMS II studies. J Neurosurg 2014;121:1354–58 doi:10.3171/2014.7.JNS131430 pmid:25259569
    CrossRefPubMed
  2. 2.↵
    IMS Study Investigators. Combined intravenous and intra-arterial recanalization for acute ischemic stroke: the Interventional Management of Stroke Study. Stroke 2004;35:904–11 doi:10.1161/01.STR.0000121641.77121.98 pmid:15017018
    Abstract/FREE Full Text
  3. 3.↵
    The IMS II Trial Investigators. The Interventional Management of Stroke (IMS) II study. Stroke 2007;38:2127–35 doi:10.1161/STROKEAHA.107.483131 pmid:17525387
    Abstract/FREE Full Text
  4. 4.↵
    2. Tomsick TA,
    3. Broderick J,
    4. Carrozella J, et al
    ; Interventional Management of Stroke II Investigators. Revascularization results in the Interventional Management of Stroke II Trial. AJNR Am J Neuroradiol 2008;29:582–87 doi:10.3174/ajnr.A0843 pmid:18337393
    Abstract/FREE Full Text
  5. 5.↵
    2. Galimanis A,
    3. Jung S,
    4. Mono ML, et al
    . Endovascular therapy of 623 patients with anterior circulation stroke. Radiology 2012;43:1052–57 doi:10.1161/STROKEAHA.111.639112 pmid:22363057
    CrossRefPubMed
  6. 6.↵
    2. Sheth S,
    3. Saver J,
    4. Jahan R, et al
    ; UCLA Comprehensive Stroke Center. M2 occlusions as targets for endovascular therapy: comprehensive analysis of diffusion/perfusion MRI, angiography, and clinical outcomes. J Neurointerv Surg 2015;7:478–83 doi:10:1136/neurointsurg-2014-011232 pmid:24821842
    Abstract/FREE Full Text
  7. 7.↵
    2. Flores A,
    3. Tomasello A,
    4. Cardona P, et al
    ; Catalan Stroke Code and Reperfusion Consortium Cat-SCR. Endovascular treatment for M2 occlusions in the era of stentrievers: a descriptive multicenter experience. J Neurointerv Surg 2015;7:234–37 doi:10:1136/neurointsurg-2014-011100 pmid:24578483
    Abstract/FREE Full Text
  8. 8.↵
    2. Tomsick TA,
    3. Khatri P,
    4. Jovin T, et al
    ; IMS III Executive Committee. Equipoise among recanalization strategies. Neurology 2010;74:1069–76 doi:10.1212/WNL.0b013e3181d76b8f pmid:20350981
    Abstract/FREE Full Text
  9. 9.↵
    2. Rahme R,
    3. Abruzzo T,
    4. Martin RH, et al
    . Is intra-arterial thrombolysis beneficial for M2 Occlusions? Subgroup analysis of the PROACT II Trial. Stroke 2013;44:240–42 doi:10.1161/STROKEAHA.112.671495 pmid:23223507
    Abstract/FREE Full Text
  10. 10.↵
    2. Goyal M,
    3. Demchuk AM,
    4. Menon BK, et al
    ; ESCAPE Trial Investigators. Randomized assessment of rapid endovascular treatment of acute stroke. N Engl J Med 2015;372:1019–30 doi:10.1056/NEJMoa1414905 pmid:25671798
    CrossRefPubMed
  11. 11.↵
    2. Campbell BC,
    3. Mitchell PJ,
    4. Kleinig TJ, et al
    ; EXTEND-IA Investigators. Endovascular therapy for ischemic stroke with perfusion-imaging selection. N Engl J Med 2015;372:1009–18 doi:10.1056/NEJMoa1414792 pmid:25671797
    CrossRefPubMed
  12. 12.↵
    2. Berkheimer OA,
    3. Fransen PS,
    4. Beumer D, et al
    ; MR CLEAN Investigators. A randomized trial of intraarterial treatment for acute stroke. N Engl J Med 2015;372:11–20 doi:10.1056/NEJMoa1414792 pmid:25517348
    CrossRefPubMedWeb of Science
  13. 13.↵
    2. Broderick JP,
    3. Palesch YY,
    4. Demchuk AM, et al
    ; Interventional Management of Stroke (IMS) III Investigators. Endovascular therapy after intravenous rt-PA alone for stroke. N Engl J Med 2013;368:893–903 doi:10.1056/NEJMoa1214300 pmid:23390923
    CrossRefPubMedWeb of Science
  14. 14.↵
    2. Khatri P,
    3. Hill M,
    4. Palesch Y, et al
    ; Interventional Management of Stroke III Investigators. Methodology of the Interventional Management of Stroke III trial. Int J Stroke 2008;3:130–37 doi:10.1111/j.1747-4949.2008.00151.x pmid:18706007
    Abstract/FREE Full Text
  15. 15.↵
    2. Yeatts SD,
    3. Martin RH,
    4. Foster LD, et al
    . Challenges of decision-making regarding futility in a randomized trial: the IMS III experience. In: Proceedings of the International Stroke Conference, Honolulu. Hawaii. February 6–8, 2013
  16. 16.↵
    2. Smith WS,
    3. Sung G,
    4. Starkman S, et al
    ; MERCI Trial Investigators. Safety and efficacy of mechanical embolectomy in acute ischemic stroke: results of the MERCI trial. Stroke 2005;36:1432–38 doi:10.1161/01.STR.0000171066.25248.1d pmid:15961709
    Abstract/FREE Full Text
  17. 17.↵
    2. Smith WS,
    3. Sung G,
    4. Saver J, et al
    . Mechanical thrombectomy for acute ischemic stroke: final results of the Multi MERCI trial. Stroke 2008;39:1205–12 doi:10.1161/STROKEAHA.107.497115 pmid:18309168
    Abstract/FREE Full Text
  18. 18.↵
    Penumbra Pivotal Stroke Trial Investigators. The Penumbra Pivotal Stroke Trial: safety and effectiveness of a new generation of mechanical devices for clot removal in intracranial large vessel occlusive disease. Stroke 2009;40:2761–68 doi:10.1161/STROKEAHA.108.544957 pmid:19590057
    Abstract/FREE Full Text
  19. 19.↵
    2. Dávalos A,
    3. Pereira VM,
    4. Chapot R, et al
    . Retrospective multicenter study of Solitaire FR for revascularization in the treatment of acute ischemic stroke. Stroke 2012;43:2699–705 doi:10.1161/STROKEAHA.112.663328 pmid:22851547
    Abstract/FREE Full Text
  20. 20.↵
    2. Tomsick T,
    3. Yeatts SD,
    4. Liebeskind D, et al
    ; IMS III Investigators. Endovascular revascularization results in IMS III: intracranial ICA and M1 occlusions. J Neurointervent Surg 2015;7:795–802 doi:10.1136/neurointsurg-2014-011318 pmid:25342652
    Abstract/FREE Full Text
  21. 21.↵
    2. Morris PP,
    3. Choi IS
    . Cerebral vascular anatomy. Neuroimaging Clin N Am 1996;6:541–60 pmid:8873092
    PubMed
  22. 22.↵
    1. Newton TH,
    2. Potts DG
    2. Ring BA
    . The middle cerebral artery. In: Newton TH, Potts DG, eds. Radiology of the Skull and Brain: Angiography. Vol 2. Great Neck: CV Mosby; 1974:1442–78
  23. 23.↵
    2. Appireddy RM,
    3. Menon BK,
    4. Horn M, et al
    . Using the M2 vessel diameter and baseline NIHSS to identify which M2 occlusions should be treated endovascularly. Stroke 2015;46:AWP56
  24. 24.↵
    2. Gulati D,
    3. Ducruet A,
    4. Aghaebrahim A, et al
    . Impact of differences in definition of M1 and M2 segment of middle cerebral artery on acute stroke endovascular therapy. Stroke 2015;46:AWMP22
  25. 25.↵
    2. Ogawa A,
    3. Mori E,
    4. Minematsu K, et al
    . Randomized trial of intraarterial infusion of urokinase within 6 hours of middle cerebral artery stroke: the middle cerebral artery embolism local fibrinolytic intervention trial (MELT) Japan. Stroke 2007;38:2633–39 doi:10.1161/STROKEAHA.107.488551 pmid:17702958
    Abstract/FREE Full Text
  26. 26.↵
    2. Zaidat OO,
    3. Yoo AJ,
    4. Khatri P, et al
    ; Cerebral Angiographic Revascularization Grading (CARG) Collaborators, STIR Revascularization Working Group, STIR Thrombolysis in Cerebral Infarction (TICI) Task Force. Recommendations on angiographic revascularization standards for acute ischemic stroke: a consensus statement. Stroke 2013;44:2650–63 doi:10.1161/STROKEAHA.113.001972 pmid:23920012
    FREE Full Text
  27. 27.↵
    2. Gibo H,
    3. Carver CC,
    4. Rhoton AL Jr., et al
    . Microsurgical anatomy of the middle cerebral artery. J Neurosurg 1981;54:151–69 doi:10.3171/jns.1981.54.2.0151 pmid:7452329
    CrossRefPubMedWeb of Science
  28. 28.↵
    2. Krayenbuhl HA,
    3. Yasargil MG
    . Cerebral Angiography. 2nd ed. Philadelphia; Lippincott; 1968
  29. 29.↵
    1. Newton TH,
    2. Potts DG
    2. Ring BA
    . The middle cerebral artery. In: Newton TH, Potts DG, eds. Radiology of the Skull and Brain: Angiography. Vol 2. Great Neck; CV Mosby; 1974:1459
  30. 30.↵
    2. Menon BK,
    3. Bal S,
    4. Modi J, et al
    . Anterior temporal artery sign in CT angiography predicts fatal brain edema and mortality in acute M1 middle cerebral artery occlusion. J Neuroimaging 2012;22:145–48 doi:10.1111/j.1552-6569.2010.00566.x pmid:21223432
    CrossRefPubMed
  31. 31.↵
    2. Livorine A,
    3. Vagal A,
    4. Shu J, et al
    . Anatomical variation of M2 occlusions and tissue at risk in IMS III trial: an exploratory analysis. In: Proceedings of the Annual Meeting of American Roentgen Ray Society, Toronto, Ontario, Canada. April 19–24, 2015
  32. 32.↵
    2. Von Kummer R,
    3. Demchuk AM,
    4. Foster LD, et al
    . Early arterial recanalization after intra-venous tissue-plasminogen-activator treatment in the Interventional Management of Stroke-3 study. Stroke 2014;45:A74
    CrossRef
  33. 33.↵
    2. Demchuk AM,
    3. Goyal M,
    4. Yeatts SD, et al
    ; IMS III Investigators. Recanalization and clinical outcome of occlusion sites at baseline CT angiography in the Interventional Management of Stroke III trial. Radiology 2014;273:202–10 doi:10.1148/radiol.14132649 pmid:24895878
    CrossRefPubMedWeb of Science
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Endovascular Therapy of M2 Occlusion in IMS III: Role of M2 Segment Definition and Location on Clinical and Revascularization Outcomes
T.A. Tomsick, J. Carrozzella, L. Foster, M.D. Hill, R. von Kummer, M. Goyal, A.M. Demchuk, P. Khatri, Y. Palesch, J.P. Broderick, S.D. Yeatts, D.S. Liebeskind, for the IMS III Investigators
American Journal of Neuroradiology Jan 2017, 38 (1) 84-89; DOI: 10.3174/ajnr.A4979
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