Index by author

The most recent 2016 WHO classification includes MVNT as a unique cytoarchitectural pattern of gangliocytoma, though it remains unclear whether MVNT is a true neoplastic process or a dysplastic hamartomatous/malformative lesion. The authors report 33 cases of presumed multinodular and vacuolating neuronal tumor of the cerebrum that exhibit a remarkably similar pattern of imaging findings consisting of a subcortical cluster of nodular lesions. They conclude that these are benign, nonaggressive lesions that do not require biopsy in asymptomatic patients and behave more like a malformative process than a true neoplasm.

The authors compared the diagnostic concordance of vessel imaging using 3D-TOF-MRA and DSA in 85 patients with primary central nervous system vasculitis. Among the 25 patients with abnormal DSA findings, 24 demonstrated abnormal 3D-TOF-MRA findings, whereas all 6 remaining patients with normal DSA findings had normal 3D-TOF-MRA findings. They conclude that 3D-TOF-MRA shows a high concordance with DSA in diagnostic performance when analyzing vasculature in patients with primary central nervous system vasculitis and that with negative 3T 3D-TOF-MRA findings, the added diagnostic value of DSA is limited.