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Review ArticleHead and Neck Imaging
Open Access

The Management and Imaging of Vestibular Schwannomas

E.P. Lin and B.T. Crane
American Journal of Neuroradiology November 2017, 38 (11) 2034-2043; DOI: https://doi.org/10.3174/ajnr.A5213
E.P. Lin
aFrom the Departments of Imaging Sciences (E.P.L.)
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B.T. Crane
bOtolaryngology (B.T.C), University of Rochester Medical Center, Rochester, New York.
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  • Fig 1.
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    Fig 1.

    Axial illustration (A) of a translabyrinthine craniotomy demonstrates exposure of the IAC and CPA, and it may be performed with or without cerebellar retraction. Intraoperative images just before (B) and following (C) the labyrinthectomy demonstrate exposure to the intracanalicular vestibular schwannoma. PA indicates porus acusticus. A is reproduced with permission from the University of Rochester.

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    Fig 2.

    Precontrast axial T1WI (A) and postcontrast axial T1WI with fat-suppression (B) demonstrate typical postoperative findings following a translabyrinthine craniotomy, with abdominal fat packing within the mastoidectomy defect (asterisk). Linear enhancement along the mastoidectomy bed reflects postsurgical changes without evidence of recurrent tumor within the IAC.

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    Fig 3.

    Axial illustration (A) of a retrosigmoid craniotomy reveals a typical exposure of the CPA and lateral IAC by drilling through the posterior meatal lip. Intraoperative image (B) reveals excellent exposure of the CPA VS and adjacent cranial nerves (CNs V, IX–XI). A second intraoperative image (C) following removal of the posterior face of the IAC wall exposes the intrameatal component of the VS (IAC VS). Immediate postoperative noncontrast axial CT (D) and a contrast-enhanced T1WI with fat-suppression (E) demonstrate a retrosigmoid craniectomy with a defect in the posterior meatal lip (arrow) and a residual extrameatal enhancing VS on the contrast-enhanced T1WI. A is reproduced with permission from the University of Rochester.

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    Fig 4.

    Coronal illustration (A) of a middle fossa craniotomy demonstrates retraction of the temporal lobe and drilling of the petrous apex over the superior semicircular canal to provide access to the IAC. Postoperative coronal reformation of noncontrast CT (B) and coronal T1WI with fat suppression (C) reveal a temporal craniotomy and absence of the IAC roof (arrows), through which the VS was accessed, and linear enhancement within the IAC, which reflects expected postsurgical changes without evidence of residual tumor. A is reproduced with permission from the University of Rochester.

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    Fig 5.

    Examples of various enhancing IAC and CPA masses on contrast-enhanced T1WI with fat-suppression (B–D, and F) and 3D echo-spoiled gradient-echo images (A and E). A, A large CPA meningioma, located eccentric to the porus acusticus (the asterisk denotes the tumor midline), extends into the IAC without the associated bony expansion often seen with VS (see Fig 6). B, An enhancing facial nerve schwannoma within the IAC extends into the labyrinthine segment (arrow), which differentiates a facial nerve from a vestibular schwannoma, as well as into the anterior genu and tympanic segments. C, A small enhancing metastatic lesion within the IAC in a patient with non-small cell lung cancer extends into the IAC fundus, labyrinthine, anterior genu, and tympanic segments. D, Perineural spread along the intratemporal and intracanicular segments of the facial nerve in a patient with squamous cell carcinoma of the periauricular skin (the asterisk indicates the anterior genu; arrow, the greater superficial petrosal nerve). E, An ill-defined tuft of enhancement within the IAC fundus extending into the labyrinthine segment (arrow) and anterior genu of the facial nerve in a patient with right Bell palsy. F, Bilateral ill-defined enhancement of the distal IAC bilaterally extending into the labyrinthine segment and anterior genu of the facial nerve canal in a patient with neurosarcoidosis.

  • Fig 6.
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    Fig 6.

    Contrast-enhanced axial T1WI (A), axial T2WI (B), and sagittal T1WI (C) reveal a large right CPA VS with asymmetric enlargement of the IAC, brain stem and cerebellar compression, peritumoral edema, and tonsillar herniation.

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    Fig 7.

    Precontrast axial T2WI (A) and postcontrast axial T1WI (B) demonstrate a small intracanalicular VS with lateral extension into the IAC fundus and the modiolus, which is associated with a decreased rate of hearing preservation.

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    Fig 8.

    Axial FIESTA reveals a large left CPA VS with multiple superficial cysts, which may indicate increased adherence to neurovascular structures and lead to a more difficult surgical resection. Note asymmetric decreased T2 signal within the left cochlea (arrow) compared with the right.

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    Fig 9.

    Two examples of post-SRS imaging. Postcontrast axial T1WI with fat suppression in a patient before (A) and following (B) SRS reveals decreased enhancement centrally within the tumor on posttherapeutic imaging (B), confirming a positive response to SRS. Two axial FIESTA images (C and D) obtained during 2 consecutive follow-up examinations in a 2-year period demonstrate interval enlargement of the cystic component within the right CPA associated with a predominantly intrameatal VS following radiation therapy. The cystic component was later resected (not shown).

Tables

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    Table 1:

    Indications, benefits, and disadvantages of lateral skull base approaches for VS resection

    TranslabyrinthineRetrosigmoidMiddle Fossa
    IndicationsUnserviceable hearing; any IAC or CPA VSVS with large CPA component; medial IAC VSSmall lateral IAC VS (<0.5 cm); small medial IAC VS with <1 cm CPA component
    AdvantagesMinimal brain retractionPanoramic CPA exposure; better facial nerve and hearing preservation for medial VSBetter exposure, lateral IAC
    DisadvantagesComplete hearing loss; difficult approach for CPA VS ventral to porus acusticus; risk for facial nerve injuryLimited access to lateral IAC; potential for cerebellar and brain stem injuryLimited PF access; temporal lobe retraction; risk for facial nerve injury
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    Table 2:

    A sample MR imaging protocol for the evaluation of VSa

    SequenceFOV (cm)Thickness and Spacing (mm)TR (ms) (or Flip Angle)TE (ms)MatrixComments
    Sag T1 FLAIR245 × 128009320 × 224(TI 858 ms)
    Ax DTI263 × 08000Min128 × 128
    Sag 3D T2 FLAIR FS271.47600120256 × 256With Ax and Cor reformations
    Ax T2 FLAIR245 × 19500125352 × 224Alternative to 3D T2 FLAIR (TI = 2250 ms)
    Ax T2 FS183 × 0.5491787320 × 320Through PF only
    Ax FIESTA180.8(45°)Min300 × 300With Ax and Sag oblique reformations
    Ax SWAN or SWI252Min (15°)25320 × 224Optional
    Sag 3D T1 FS+C251.2600Min288 × 288With Ax and Cor reformations
    Ax 3D SPGR+C251.5(20°)Min320 × 224For treatment planning; nonangled orthogonal Ax
    Ax T1 FS+C183 × 0.52723.522320 × 320Alternative to 3D T1 FS +C (TI = 111 ms)
    Cor T1 FS+C183 × 0.52475Min383 × 224Alternative to 3D T1 FS +C (TI = 111 ms)
    • Note:—SPGR indicates echo-spoiled gradient echo; FS, fat suppression; C, contrast; Sag, sagittal; Ax, axial; Cor, coronal; SWAN, T2 star-weighted angiography; Min, minimum.

    • ↵a Except for the axial 3D SPGR+C, all sequences are referenced to the anterior/posterior commissure line. An axial T2 FLAIR can be performed instead of the sagittal 3D T2 FLAIR. An axial and coronal T1 FS+C can be performed in lieu of a sagittal 3D T1 FS+C.

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American Journal of Neuroradiology: 38 (11)
American Journal of Neuroradiology
Vol. 38, Issue 11
1 Nov 2017
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Cite this article
E.P. Lin, B.T. Crane
The Management and Imaging of Vestibular Schwannomas
American Journal of Neuroradiology Nov 2017, 38 (11) 2034-2043; DOI: 10.3174/ajnr.A5213

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The Management and Imaging of Vestibular Schwannomas
E.P. Lin, B.T. Crane
American Journal of Neuroradiology Nov 2017, 38 (11) 2034-2043; DOI: 10.3174/ajnr.A5213
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Cited By...

  • Peritumoral Hyperintense Signal on Postcontrast FLAIR Images Surrounding Vestibular Schwannomas following Stereotactic Radiosurgery
  • Defining tumor growth in vestibular schwannomas: a volumetric inter-observer variability study in contrast-enhanced T1-weighted MRI
  • Peritumoral Signal on Postcontrast FLAIR Images: Description and Proposed Biomechanism in Vestibular Schwannomas
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  • Hydrops Herniation into the Semicircular Canals
  • ASL Sensitivity for Head and Neck Paraganglioma
  • Post SRS Peritumoral Hyperintense Signal of VSs
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