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Research ArticleADULT BRAIN
Open Access

Utility of a Multiparametric Quantitative MRI Model That Assesses Myelin and Edema for Evaluating Plaques, Periplaque White Matter, and Normal-Appearing White Matter in Patients with Multiple Sclerosis: A Feasibility Study

A. Hagiwara, M. Hori, K. Yokoyama, M.Y. Takemura, C. Andica, K.K. Kumamaru, M. Nakazawa, N. Takano, H. Kawasaki, S. Sato, N. Hamasaki, A. Kunimatsu and S. Aoki
American Journal of Neuroradiology February 2017, 38 (2) 237-242; DOI: https://doi.org/10.3174/ajnr.A4977
A. Hagiwara
aFrom the Department of Radiology (A.H., A.K.), Graduate School of Medicine, University of Tokyo, Tokyo, Japan
bDepartments of Radiology (A.H., M.H., M.Y.T., C.A., K.K.K., M.N., N.T., H.K., S.S., N.H., S.A.)
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  • ORCID record for A. Hagiwara
M. Hori
bDepartments of Radiology (A.H., M.H., M.Y.T., C.A., K.K.K., M.N., N.T., H.K., S.S., N.H., S.A.)
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K. Yokoyama
cNeurology (K.Y.), Juntendo University School of Medicine, Tokyo, Japan
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M.Y. Takemura
bDepartments of Radiology (A.H., M.H., M.Y.T., C.A., K.K.K., M.N., N.T., H.K., S.S., N.H., S.A.)
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C. Andica
bDepartments of Radiology (A.H., M.H., M.Y.T., C.A., K.K.K., M.N., N.T., H.K., S.S., N.H., S.A.)
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K.K. Kumamaru
bDepartments of Radiology (A.H., M.H., M.Y.T., C.A., K.K.K., M.N., N.T., H.K., S.S., N.H., S.A.)
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M. Nakazawa
bDepartments of Radiology (A.H., M.H., M.Y.T., C.A., K.K.K., M.N., N.T., H.K., S.S., N.H., S.A.)
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N. Takano
bDepartments of Radiology (A.H., M.H., M.Y.T., C.A., K.K.K., M.N., N.T., H.K., S.S., N.H., S.A.)
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H. Kawasaki
bDepartments of Radiology (A.H., M.H., M.Y.T., C.A., K.K.K., M.N., N.T., H.K., S.S., N.H., S.A.)
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S. Sato
bDepartments of Radiology (A.H., M.H., M.Y.T., C.A., K.K.K., M.N., N.T., H.K., S.S., N.H., S.A.)
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N. Hamasaki
bDepartments of Radiology (A.H., M.H., M.Y.T., C.A., K.K.K., M.N., N.T., H.K., S.S., N.H., S.A.)
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A. Kunimatsu
aFrom the Department of Radiology (A.H., A.K.), Graduate School of Medicine, University of Tokyo, Tokyo, Japan
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S. Aoki
bDepartments of Radiology (A.H., M.H., M.Y.T., C.A., K.K.K., M.N., N.T., H.K., S.S., N.H., S.A.)
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Article Information

vol. 38 no. 2 237-242
DOI 
https://doi.org/10.3174/ajnr.A4977
PubMed 
27789453

Published By 
American Journal of Neuroradiology
Print ISSN 
0195-6108
Online ISSN 
1936-959X
History 
  • Received June 13, 2016
  • Accepted after revision August 29, 2016
  • Published online February 13, 2017.

Copyright & Usage 
© 2017 by American Journal of Neuroradiology Indicates open access to non-subscribers at www.ajnr.org

Author Information

  1. A. Hagiwaraa,b,
  2. M. Horib,
  3. K. Yokoyamac,
  4. M.Y. Takemurab,
  5. C. Andicab,
  6. K.K. Kumamarub,
  7. M. Nakazawab,
  8. N. Takanob,
  9. H. Kawasakib,
  10. S. Satob,
  11. N. Hamasakib,
  12. A. Kunimatsua and
  13. S. Aokib
  1. aFrom the Department of Radiology (A.H., A.K.), Graduate School of Medicine, University of Tokyo, Tokyo, Japan
  2. bDepartments of Radiology (A.H., M.H., M.Y.T., C.A., K.K.K., M.N., N.T., H.K., S.S., N.H., S.A.)
  3. cNeurology (K.Y.), Juntendo University School of Medicine, Tokyo, Japan
  4. dDepartment of Radiological Sciences (M.N.), Graduate School of Human Health Sciences, Tokyo Metropolitan University, Tokyo, Japan.
  1. Please address correspondence to Akifumi Hagiwara, MD, Department of Radiology, Graduate School of Medicine, University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo, Japan, 113-8655; e-mail: ahagiwara-tky{at}umin.ac.jp
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American Journal of Neuroradiology: 38 (2)
American Journal of Neuroradiology
Vol. 38, Issue 2
1 Feb 2017
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Utility of a Multiparametric Quantitative MRI Model That Assesses Myelin and Edema for Evaluating Plaques, Periplaque White Matter, and Normal-Appearing White Matter in Patients with Multiple Sclerosis: A Feasibility Study
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Cite this article
A. Hagiwara, M. Hori, K. Yokoyama, M.Y. Takemura, C. Andica, K.K. Kumamaru, M. Nakazawa, N. Takano, H. Kawasaki, S. Sato, N. Hamasaki, A. Kunimatsu, S. Aoki
Utility of a Multiparametric Quantitative MRI Model That Assesses Myelin and Edema for Evaluating Plaques, Periplaque White Matter, and Normal-Appearing White Matter in Patients with Multiple Sclerosis: A Feasibility Study
American Journal of Neuroradiology Feb 2017, 38 (2) 237-242; DOI: 10.3174/ajnr.A4977

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Utility of a Multiparametric Quantitative MRI Model That Assesses Myelin and Edema for Evaluating Plaques, Periplaque White Matter, and Normal-Appearing White Matter in Patients with Multiple Sclerosis: A Feasibility Study
A. Hagiwara, M. Hori, K. Yokoyama, M.Y. Takemura, C. Andica, K.K. Kumamaru, M. Nakazawa, N. Takano, H. Kawasaki, S. Sato, N. Hamasaki, A. Kunimatsu, S. Aoki
American Journal of Neuroradiology Feb 2017, 38 (2) 237-242; DOI: 10.3174/ajnr.A4977
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