To tPA or Not to tPA, That Is the Question

REFERENCES

1. 1.↵
   2. Berkhemer OA,
   3. Fransen PS,
   4. Beumer D, et al

   . A randomized trial of intraarterial treatment for acute ischemic stroke. N Engl J Med 2015;372:11–20 doi:10.1056/NEJMoa1411587 pmid:25517348

   CrossRefPubMedWeb of Science
2. 2.↵
   2. Campbell BC,
   3. Mitchell PJ,
   4. Kleinig TJ, et al

   ; EXTEND-IA Investigators. Endovascular therapy for ischemic stroke with perfusion-imaging selection. N Engl J Med 2015;372:1009–18 doi:10.1056/NEJMoa1414792 pmid:25671797

   CrossRefPubMed
3. 3.↵
   2. Goyal M,
   3. Demchuk AM,
   4. Menon BK, et al

   ; ESCAPE Trial Investigators. Randomized assessment of rapid endovascular treatment of ischemic stroke. N Engl J Med 2015;372:1019–30 doi:10.1056/NEJMoa1414905 pmid:25671798

   CrossRefPubMed
4. 4.↵
   2. Jovin TG,
   3. Chamorro A,
   4. Cobo E, et al

   ; REVASCAT Trial Investigators. Thrombectomy within 8 hours after symptom onset in ischemic stroke. N Engl J Med 2015;372:2296–306 doi:10.1056/NEJMoa1503780 pmid:25882510

   CrossRefPubMed
5. 5.↵
   2. Saver JL,
   3. Goyal M,
   4. Bonafe A, et al

   ; SWIFT PRIME Investigators. Stent-retriever thrombectomy after intravenous t-PA vs. t-PA alone in stroke. N Engl J Med 2015;372:2285–95 doi:10.1056/NEJMoa1415061 pmid:25882376

   CrossRefPubMed
6. 6.↵
   2. Goyal M,
   3. Menon BK,
   4. van Zwam WH, et al

   ; HERMES collaborators. Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials. Lancet 2016;387:1723–31 doi:10.1016/S0140-6736(16)00163-X pmid:26898852

   CrossRefPubMed
7. 7.↵
   2. Bracard S,
   3. Ducrocq X,
   4. Mas JL, et al

   ; THRACE investigators. Mechanical thrombectomy after intravenous alteplase versus alteplase alone after stroke (THRACE): a randomised controlled trial. Lancet Neurol 2016;15:1138–47 doi:10.1016/S1474-4422(16)30177-6 pmid:27567239

   CrossRefPubMed
8. 8.↵
   2. Weber R,
   3. Nordmeyer H,
   4. Hadisurya J, et al

   . Comparison of outcome and interventional complication rate in patients with acute stroke treated with mechanical thrombectomy with and without bridging thrombolysis. J Neurointerv Surg 2017;9:229–33 doi:10.1136/neurintsurg-2015-012236 pmid:26902926

   Abstract/FREE Full Text
9. 9.↵
   2. Broeg-Morvay A,
   3. Mordasini P,
   4. Bernasconi C, et al

   . Direct mechanical intervention versus combined intravenous and mechanical intervention in large artery anterior circulation stroke: a matched-pairs analysis. Stroke 2016;47:1037–44 doi:10.1161/STROKEAHA.115.011134 pmid:26906917

   Abstract/FREE Full Text
10. 10.↵
    2. Coutinho JM,
    3. Liebeskind DS,
    4. Slater LA, et al

    . Combined intravenous thrombolysis and thrombectomy vs thrombectomy alone for acute ischemic stroke: a pooled analysis of the SWIFT and STAR studies. JAMA Neurol 2017;74:268–74 doi:10.1001/jamaneurol.2016.5374 pmid:28097310

    CrossRefPubMed
11. 11.↵
    2. Chandra RV,
    3. Leslie-Mazwi TM,
    4. Mehta BP, et al

    . Does the use of IV tPA in the current era of rapid and predictable recanalization by mechanical embolectomy represent good value? J Neurointerv Surg 2016;8:443–46 doi:10.1136/neurintsurg-2015-012231 pmid:26758911

    Abstract/FREE Full Text
12. 12.↵
    2. Hirsch JA,
    3. Harvey HB,
    4. Barr RM, et al

    . Sustainable growth rate repealed, MACRA revealed: historical context and analysis of recent changes in Medicare physician payment methodologies. AJNR Am J Neuroradiol 2016;37:210–14 doi:10.3174/ajnr.A4522 pmid:26585253

    FREE Full Text
13. 13.↵
    2. Shireman TI,
    3. Wang K,
    4. Saver JL, et al

    ; SWIFT-PRIME Investigators. Cost-effectiveness of Solitaire stent retriever thrombectomy for acute ischemic stroke: results from the SWIFT-PRIME trial (Solitaire With the Intention for Thrombectomy as Primary Endovascular Treatment for Acute Ischemic Stroke). Stroke 2017;48:379–87 doi:10.1161/STROKEAHA.116.014735 pmid:28028150

    Abstract/FREE Full Text