Value of Thrombus CT Characteristics in Patients with Acute Ischemic Stroke

References

1. 1.↵
   2. Berkhemer OA,
   3. Fransen PS,
   4. Beumer D, et al

   ; MR CLEAN Investigators. A randomized trial of intraarterial treatment for acute ischemic stroke. N Engl J Med 2015;372:11–20 doi:10.1056/NEJMoa1411587 pmid:25517348

   CrossRefPubMedWeb of Science
2. 2.↵
   2. Campbell BC,
   3. Mitchell PJ,
   4. Kleinig TJ, et al

   ; EXTEND-IA Investigators. Endovascular therapy for ischemic stroke with perfusion-imaging selection. N Engl J Med 2015;372:1009–18 doi:10.1056/NEJMoa1414792 pmid:25671797

   CrossRefPubMed
3. 3.↵
   2. Goyal M,
   3. Demchuk AM,
   4. Menon BK, et al

   ; ESCAPE Trial Investigators. Randomized assessment of rapid endovascular treatment of ischemic stroke. N Engl J Med 2015;372:1019–30 doi:10.1056/NEJMoa1414905 pmid:25671798

   CrossRefPubMed
4. 4.↵
   2. Saver JL,
   3. Goyal M,
   4. Bonafe A, et al

   ; SWIFT PRIME Investigators. Stent-retriever thrombectomy after intravenous t-PA vs. t-PA alone in stroke. N Engl J Med 2015;372:2285–95 doi:10.1056/NEJMoa1415061 pmid:25882376

   CrossRefPubMed
5. 5.↵
   2. Jovin TG,
   3. Chamorro A,
   4. Cobo E, et al

   ; REVASCAT Trial Investigators. Thrombectomy within 8 hours after symptom onset in ischemic stroke. N Engl J Med 2015;372:2296–306 doi:10.1056/NEJMoa1503780 pmid:25882510

   CrossRefPubMed
6. 6.↵
   2. Kamalian S,
   3. Morais LT,
   4. Pomerantz SR, et al

   . Clot length distribution and predictors in anterior circulation stroke: implications for intra-arterial therapy. Stroke 2013;44:3553–56 doi:10.1161/STROKEAHA.113.003079 pmid:24105699

   Abstract/FREE Full Text
7. 7.↵
   2. Riedel CH,
   3. Zimmermann P,
   4. Jensen-Kondering U, et al

   . The importance of size: successful recanalization by intravenous thrombolysis in acute anterior stroke depends on thrombus length. Stroke 2011;42:1775–77 doi:10.1161/STROKEAHA.110.609693 pmid:21474810

   Abstract/FREE Full Text
8. 8.↵
   2. Lobsien D,
   3. Gawlitza M,
   4. Schaudinn A, et al

   . Mechanical thrombectomy versus systemic thrombolysis in MCA stroke: a distance to thrombus-based outcome analysis. J Neurointerv Surg 2016;8:878–82 doi:10.1136/neurintsurg-2015-011964 pmid:26346459

   Abstract/FREE Full Text
9. 9.↵
   2. Mokin M,
   3. Morr S,
   4. Natarajan SK, et al

   . Thrombus density predicts successful recanalization with Solitaire stent retriever thrombectomy in acute ischemic stroke. J Neurointerv Surg 2015;7:104–07 doi:10.1136/neurintsurg-2013-011017 pmid:24510378

   Abstract/FREE Full Text
10. 10.↵
    2. Moftakhar P,
    3. English JD,
    4. Cooke DL, et al

    . Density of thrombus on admission CT predicts revascularization efficacy in large vessel occlusion acute ischemic stroke. Stroke 2013;44:243–45 doi:10.1161/STROKEAHA.112.674127 pmid:23111438

    Abstract/FREE Full Text
11. 11.↵
    2. Puig J,
    3. Pedraza S,
    4. Demchuk A, et al

    . Quantification of thrombus Hounsfield units on noncontrast CT predicts stroke subtype and early recanalization after intravenous recombinant tissue plasminogen activator. AJNR Am J Neuroradiol 2012;33:90–96 doi:10.3174/ajnr.A2878 pmid:22158924

    Abstract/FREE Full Text
12. 12.↵
    2. Niesten JM,
    3. van der Schaaf IC,
    4. van der Graaf Y, et al

    . Predictive value of thrombus attenuation on thin-slice non-contrast CT for persistent occlusion after intravenous thrombolysis. Cerebrovasc Dis 2014;37:116–22 doi:10.1159/000357420 pmid:24435107

    CrossRefPubMed
13. 13.↵
    2. Santos EM,
    3. Marquering HA,
    4. den Blanken MD, et al

    ; MR CLEAN Investigators. Thrombus permeability is associated with improved functional outcome and recanalization in patients with ischemic stroke. Stroke 2016;47:732–41 doi:10.1161/STROKEAHA.115.011187 pmid:26846859

    Abstract/FREE Full Text
14. 14.↵
    2. Fransen PSS,
    3. Beumer D,
    4. Berkhemer OA, et al

    ; MR CLEAN Investigators. MR CLEAN, a multicenter randomized clinical trial of endovascular treatment for acute ischemic stroke in the Netherlands: study protocol for a randomized controlled trial. Trials 2014;15:343 doi:10.1186/1745-6215-15-343 pmid:25179366

    CrossRefPubMed
15. 15.↵
    2. Santos EM,
    3. Marquering HA,
    4. Berkhemer OA, et al

    ; MR CLEAN Investigators. Development and validation of intracranial thrombus segmentation on CT angiography in patients with acute ischemic stroke. PLoS One 2014;9:e101985 doi:10.1371/journal.pone.0101985 pmid:25032691

    CrossRefPubMed
16. 16.↵
    2. van Swieten JC,
    3. Koudstaal PJ,
    4. Visser MC, et al

    . Interobserver agreement for the assessment of handicap in stroke patients. Stroke 1988;19:604–07 doi:10.1161/01.STR.20.6.828 pmid:3363593

    Abstract/FREE Full Text
17. 17.↵
    2. Saver JL

    . Novel end point analytic techniques and interpreting shifts across the entire range of outcome scales in acute stroke trials. Stroke 2007;38:3055–62 doi:10.1161/STROKEAHA.107.488536 pmid:17916765

    Abstract/FREE Full Text
18. 18.↵
    2. Nunn A,
    3. Bath PM,
    4. Gray LJ

    . Analysis of the modified Rankin scale in randomised controlled trials of acute ischaemic stroke: a systematic review. Stroke Res Treat 2016;2016:9482876 doi:10.1155/2016/9482876 pmid:27088036

    CrossRefPubMed
19. 19.↵
    2. Boers AM,
    3. Marquering HA,
    4. Jochem JJ, et al

    ; MR CLEAN Investigators. Automated cerebral infarct volume measurement in follow-up noncontrast CT scans of patients with acute ischemic stroke. AJNR Am J Neuroradiol 2013;34:1522–27 doi:10.3174/ajnr.A3463 pmid:23471018

    Abstract/FREE Full Text
20. 20.↵
    2. Zaidat OO,
    3. Yoo AJ,
    4. Khatri P, et al

    ; Cerebral Angiographic Revascularization Grading (CARG) Collaborators, STIR Revascularization Working Group, STIR Thrombolysis in Cerebral Infarction (TICI) Task Force. Recommendations on angiographic revascularization grading standards for acute ischemic stroke: a consensus statement. Stroke 2013;44:2650–63 doi:10.1161/STROKEAHA.113.001972 pmid:23920012

    FREE Full Text
21. 21.↵
    1. Gail M,
    2. Krickeberg K,
    3. Samet J, et al.

    2. Steyerberg EW

    . Coding of categorical and contiuous predictors. In: Gail M, Krickeberg K, Samet J, et al., eds. Clinical Prediction Models: A Practical Approach to Development, Validation, and Updating (Statistics for Biology and Health). New York: Springer-Verlag; 2009:159–73 doi:10.1007/978-0-387-77244-8

    CrossRef
22. 22.↵
    2. Yilmaz U,
    3. Roth C,
    4. Reith W, et al

    . Thrombus attenuation does not predict angiographic results of mechanical thrombectomy with stent retrievers. AJNR Am J Neuroradiol 2013;34:2184–86 doi:10.3174/ajnr.A3565 pmid:23721900

    Abstract/FREE Full Text
23. 23.↵
    2. Spiotta AM,
    3. Vargas J,
    4. Hawk H, et al

    . Hounsfield unit value and clot length in the acutely occluded vessel and time required to achieve thrombectomy: complications and outcome. J Neurointervent Surg 2014;6:423–27 doi:10.1136/neurintsurg-2013-010765 pmid:23904449

    Abstract/FREE Full Text
24. 24.↵
    2. New PF,
    3. Aronow S

    . Attenuation measurements of whole blood and blood fractions in computed tomography. Radiology 1976;121:635–40 doi:10.1148/121.3.635 pmid:981659

    CrossRefPubMedWeb of Science
25. 25.↵
    2. Friedrich B,
    3. Gawlitza M,
    4. Schob S, et al

    . Distance to thrombus in acute middle cerebral artery occlusion: a predictor of outcome after intravenous thrombolysis for acute ischemic stroke. Stroke 2015;46:692–96 doi:10.1161/STROKEAHA.114.008454 pmid:25649802

    Abstract/FREE Full Text
26. 26.↵
    2. Riedel CH,
    3. Jensen U,
    4. Rohr A, et al

    . Assessment of thrombus in acute middle cerebral artery occlusion using thin-slice nonenhanced computed tomography reconstructions. Stroke 2010;41:1659–64 doi:10.1161/STROKEAHA.110.580662 pmid:20595670

    Abstract/FREE Full Text
27. 27.↵
    2. Santos EM,
    3. Yoo AJ,
    4. Beenen LF, et al

    ; MR CLEAN Investigators. Observer variability of absolute and relative thrombus density measurements in patients with acute ischemic stroke. Neuroradiology 2016;58:133–39 doi:10.1007/s00234-015-1607-4 pmid:26494462

    CrossRefPubMed
28. 28.↵
    2. Mishra SM,
    3. Dykeman J,
    4. Sajobi TT, et al

    . Early reperfusion rates with IV tPA are determined by CTA clot characteristics. AJNR Am J Neuroradiol 2014;35:2265–72 doi:10.3174/ajnr.A4048 pmid:25059699

    Abstract/FREE Full Text
29. 29.↵
    2. Frölich AM,
    3. Psychogios MN,
    4. Klotz E, et al

    . Antegrade flow across incomplete vessel occlusions can be distinguished from retrograde collateral flow using 4-dimensional computed tomographic angiography. Stroke 2012;43:2974–79 doi:10.1161/STROKEAHA.112.668889 pmid:22961960

    Abstract/FREE Full Text