Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • AJNR Case Collection
    • Case of the Week Archive
    • Classic Case Archive
    • Case of the Month Archive
  • Special Collections
    • Spinal CSF Leak Articles (Jan 2020-June 2024)
    • 2024 AJNR Journal Awards
    • Most Impactful AJNR Articles
  • Multimedia
    • AJNR Podcast
    • AJNR Scantastics
    • Video Articles
  • For Authors
    • Submit a Manuscript
    • Author Policies
    • Fast publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Manuscript Submission Guidelines
    • Imaging Protocol Submission
    • Submit a Case for the Case Collection
  • About Us
    • About AJNR
    • Editorial Board
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Other Publications
    • ajnr

User menu

  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

ASHNR American Society of Functional Neuroradiology ASHNR American Society of Pediatric Neuroradiology ASSR
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • AJNR Case Collection
    • Case of the Week Archive
    • Classic Case Archive
    • Case of the Month Archive
  • Special Collections
    • Spinal CSF Leak Articles (Jan 2020-June 2024)
    • 2024 AJNR Journal Awards
    • Most Impactful AJNR Articles
  • Multimedia
    • AJNR Podcast
    • AJNR Scantastics
    • Video Articles
  • For Authors
    • Submit a Manuscript
    • Author Policies
    • Fast publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Manuscript Submission Guidelines
    • Imaging Protocol Submission
    • Submit a Case for the Case Collection
  • About Us
    • About AJNR
    • Editorial Board
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds

Welcome to the new AJNR, Updated Hall of Fame, and more. Read the full announcements.


AJNR is seeking candidates for the position of Associate Section Editor, AJNR Case Collection. Read the full announcement.

 

Research ArticlePeripheral Nervous System

Gadolinium DTPA Enhancement Characteristics of the Rat Sciatic Nerve after Crush Injury at 4.7T

B.J. Hill, K.R. Padgett, V. Kalra, A. Marcillo, B. Bowen, P. Pattany, D. Dietrich and R. Quencer
American Journal of Neuroradiology January 2018, 39 (1) 177-183; DOI: https://doi.org/10.3174/ajnr.A5437
B.J. Hill
aFrom the Departments of Radiology (B.J.H., K.R.P., B.B., P.P., R.Q.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for B.J. Hill
K.R. Padgett
aFrom the Departments of Radiology (B.J.H., K.R.P., B.B., P.P., R.Q.)
bRadiation Oncology (K.R.P.)
cBiomedical Engineering (K.R.P.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for K.R. Padgett
V. Kalra
eMiller School of Medicine (V.K.), University of Miami, Miami, Florida.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for V. Kalra
A. Marcillo
dMiami Project to Cure Paralysis (A.M., D.D.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for A. Marcillo
B. Bowen
aFrom the Departments of Radiology (B.J.H., K.R.P., B.B., P.P., R.Q.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
P. Pattany
aFrom the Departments of Radiology (B.J.H., K.R.P., B.B., P.P., R.Q.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for P. Pattany
D. Dietrich
dMiami Project to Cure Paralysis (A.M., D.D.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for D. Dietrich
R. Quencer
aFrom the Departments of Radiology (B.J.H., K.R.P., B.B., P.P., R.Q.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for R. Quencer
  • Article
  • Figures & Data
  • Supplemental
  • Info & Metrics
  • Responses
  • References
  • PDF
Loading

References

  1. 1.↵
    1. Noble J,
    2. Munro CA,
    3. Prasad VS
    . Analysis of upper and lower extremity peripheral nerve injuries in a population of patients with multiple injuries. J Trauma 1998;45:116–22 doi:10.1097/00005373-199807000-00025 pmid:9680023
    CrossRefPubMedWeb of Science
  2. 2.↵
    1. Taylor CA,
    2. Braza D,
    3. Rice JB, et al
    . The incidence of peripheral nerve injury in extremity trauma. Am J Phys Med Rehabil 2008;87:381–85 doi:10.1097/PHM.0b013e31815e6370 pmid:18334923
    CrossRefPubMed
  3. 3.↵
    1. Schwartzman RJ,
    2. Grothusen J,
    3. Kiefer TR, et al
    . Neuropathic central pain: epidemiology, etiology, and treatment options. Arch Neurol 2001;58:1547–50 doi:10.1001/archneur.58.10.1547 pmid:11594911
    CrossRefPubMedWeb of Science
  4. 4.↵
    1. Grinsell D,
    2. Keating CP
    . Peripheral nerve reconstruction after injury: a review of clinical and experimental therapies. Biomed Res Int 2014;2014:698256 doi:10.1155/2014/698256 pmid:25276813
    CrossRefPubMed
  5. 5.↵
    1. Ruijs AC,
    2. Jaquet JB,
    3. Kalmijn S, et al
    . Median and ulnar nerve injuries: a meta-analysis of predictors of motor and sensory recovery after modern microsurgical nerve repair. Plast Reconstr Surg 2005;116:484–94; discussion 495–96 doi:10.1097/01.prs.0000172896.86594.07 pmid:16079678
    CrossRefPubMed
  6. 6.↵
    1. Sunderland S
    . Nerve Injuries and Their Repair: A Critical Appraisal. Edinburgh: Churchill Livingstone, 1991
  7. 7.↵
    1. Simon NG,
    2. Spinner RJ,
    3. Kline DG, et al
    . Advances in the neurological and neurosurgical management of peripheral nerve trauma. J Neurol Neurosurg Psychiatry 2016;87:198–208 doi:10.1136/jnnp-2014-310175 pmid:25922080
    Abstract/FREE Full Text
  8. 8.↵
    1. Feinberg J
    . EMG: myths and facts. HSS J 2006;2:19–21 doi:10.1007/s11420-005-0124-0 pmid:18751841
    CrossRefPubMed
  9. 9.↵
    1. Chhabra A,
    2. Ahlawat S,
    3. Belzberg A, et al
    . Peripheral nerve injury grading simplified on MR neurography: as referenced to Seddon and Sunderland classifications. Indian J Radiol Imaging 2014;24:217–24 doi:10.4103/0971-3026.137025 pmid:25114384
    CrossRefPubMed
  10. 10.↵
    1. Liao CD,
    2. Zhang F,
    3. Guo RM, et al
    . Peripheral nerve repair: monitoring by using gadofluorine M-enhanced MR imaging with chitosan nerve conduits with cultured mesenchymal stem cells in rat model of neurotmesis. Radiology 2012;262:161–71 doi:10.1148/radiol.11110911 pmid:22056686
    CrossRefPubMed
  11. 11.↵
    1. Li HJ,
    2. Zhang X,
    3. Zhang F, et al
    . Enhanced repair effect of toll-like receptor 4 activation on neurotmesis: assessment using MR neurography. AJNR Am J Neuroradiol 2014;35:1608–14 doi:10.3174/ajnr.A3977 pmid:24874529
    Abstract/FREE Full Text
  12. 12.↵
    1. Chen YY,
    2. Zhang X,
    3. Lin XF, et al
    . DTI metrics can be used as biomarkers to determine the therapeutic effect of stem cells in acute peripheral nerve injury. J Magn Reson Imaging 2017;45:855–62 doi:10.1002/jmri.25395 pmid:27448779
    CrossRefPubMed
  13. 13.↵
    1. Tofts PS
    . T1-weighted DCE imaging concepts: modelling, acquisition and analysis. http://www.paul-tofts-phd.org.uk/DCE-MRI_siemens.pdf. Accessed May 30, 2017.
  14. 14.↵
    1. Kobayashi S,
    2. Meir A,
    3. Baba H, et al
    . Imaging of intraneural edema by using gadolinium-enhanced MR imaging: experimental compression injury. AJNR Am J Neuroradiol 2005;26:973–80 pmid:15814956
    Abstract/FREE Full Text
  15. 15.↵
    1. Ubogu EE
    . The molecular and biophysical characterization of the human blood-nerve barrier: current concepts. J Vasc Res 2013;50:289–303 doi:10.1159/000353293 pmid:23839247
    CrossRefPubMed
  16. 16.↵
    1. Bouldin TW,
    2. Earnhardt TS,
    3. Goines ND
    . Restoration of the blood-nerve barrier in neuropathy is associated with axonal regeneration and remyelination. J Neuropathol Exp Neurol 1991;50:719–28 doi:10.1097/00005072-199111000-00004 pmid:1748880
    CrossRefPubMed
  17. 17.↵
    1. Kanda T
    . Biology of the blood-nerve barrier and its alteration in immune mediated neuropathies. J Neurol Neurosurg Psychiatry 2013;84:208–12 doi:10.1136/jnnp-2012-302312 pmid:23243216
    Abstract/FREE Full Text
  18. 18.↵
    1. Omura K,
    2. Ohbayashi M,
    3. Sano M, et al
    . The recovery of blood-nerve barrier in crush nerve injury: a quantitative analysis utilizing immunohistochemistry. Brain Res 2004;1001:13–21 doi:10.1016/j.brainres.2003.10.067 pmid:14972650
    CrossRefPubMedWeb of Science
  19. 19.↵
    1. Seitz RJ,
    2. Reiners K,
    3. Himmelmann F, et al
    . The blood-nerve barrier in Wallerian degeneration: a sequential long-term study. Muscle Nerve 1989;12:627–35 doi:10.1002/mus.880120803 pmid:2506446
    CrossRefPubMedWeb of Science
  20. 20.↵
    1. Bridge PM,
    2. Ball DJ,
    3. Mackinnon SE, et al
    . Nerve crush injuries: a model for axonotmesis. Exp Neurol 1994;127:284–90 doi:10.1006/exnr.1994.1104 pmid:8033968
    CrossRefPubMedWeb of Science
  21. 21.↵
    1. Yanagida M
    . MRI enhancement of the facial nerve with Gd-DTPA: first report—experimental study on the enhancement mechanism used in viewing vascular permeability of the facial nerve [in Japanese]. Nihon Jibiinkoka Gakkai Kaiho 1993;96:1320–28 doi:10.3950/jibiinkoka.96.1320 pmid:8377064
    CrossRefPubMed
  22. 22.↵
    1. Aagaard BD,
    2. Lazar DA,
    3. Lankerovich L, et al
    . High-resolution magnetic resonance imaging is a noninvasive method of observing injury and recovery in the peripheral nervous system. Neurosurgery 2003;53:199–203; discussion 203–04 doi:10.1227/01.NEU.0000069534.43067.28 pmid:12823890
    CrossRefPubMedWeb of Science
  23. 23.↵
    1. Bendszus M,
    2. Wessig C,
    3. Solymosi L, et al
    . MRI of peripheral nerve degeneration and regeneration: correlation with electrophysiology and histology. Exp Neurol 2004;188:171–77 doi:10.1016/j.expneurol.2004.03.025 pmid:15191813
    CrossRefPubMedWeb of Science
  24. 24.↵
    1. Stoll G,
    2. Wessig C,
    3. Gold R, et al
    . Assessment of lesion evolution in experimental autoimmune neuritis by gadofluorine M-enhanced MR neurography. Exp Neurol 2006;197:150–56 doi:10.1016/j.expneurol.2005.09.003 pmid:16199036
    CrossRefPubMed
  25. 25.↵
    1. Wessig C,
    2. Bendszus M,
    3. Stoll G
    . In vivo visualization of focal demyelination in peripheral nerves by gadofluorine M-enhanced magnetic resonance imaging. Exp Neurol 2007;204:14–19 doi:10.1016/j.expneurol.2006.09.022 pmid:17112515
    CrossRefPubMed
  26. 26.↵
    1. Wessig C,
    2. Jestaedt L,
    3. Sereda MW, et al
    . Gadofluorine M-enhanced magnetic resonance nerve imaging: comparison between acute inflammatory and chronic degenerative demyelination in rats. Exp Neurol 2008;210:137–43 doi:10.1016/j.expneurol.2007.10.014 pmid:18061168
    CrossRefPubMedWeb of Science
  27. 27.↵
    1. Bendszus M,
    2. Wessig C,
    3. Schütz A, et al
    . Assessment of nerve degeneration by gadofluorine M-enhanced magnetic resonance imaging. Ann Neurol 2005;57:388–95 doi:10.1002/ana.20404 pmid:15732113
    CrossRefPubMedWeb of Science
  28. 28.↵
    1. Skorpil M,
    2. Engström M,
    3. Nordell A
    . Diffusion-direction-dependent imaging: a novel MRI approach for peripheral nerve imaging. Magn Reson Imaging 2007;25:406–11 doi:10.1016/j.mri.2006.09.017 pmid:17371732
    CrossRefPubMed
  29. 29.↵
    1. Takagi T,
    2. Nakamura M,
    3. Yamada M, et al
    . Visualization of peripheral nerve degeneration and regeneration: monitoring with diffusion tensor tractography. Neuroimage 2009;44:884–92 doi:10.1016/j.neuroimage.2008.09.022 pmid:18948210
    CrossRefPubMed
  30. 30.↵
    1. Morisaki S,
    2. Kawai Y,
    3. Umeda , et al
    . In vivo assessment of peripheral nerve regeneration by diffusion tensor imaging. J Magn Reson Imaging 2011;33:535–42 doi:10.1002/jmri.22442 pmid:21287654
    CrossRefPubMed
  31. 31.↵
    1. Sun C,
    2. Hou Z,
    3. Hong G, et al
    . In vivo evaluation of sciatic nerve crush injury using diffusion tensor imaging: correlation with nerve function and histology. J Comput Assist Tomogr 2014;38:790–96 doi:10.1097/RCT.0000000000000118 pmid:24943253
    CrossRefPubMed
  32. 32.↵
    1. Yamasaki T,
    2. Fujiwara H,
    3. Oda R, et al
    . In vivo evaluation of rabbit sciatic nerve regeneration with diffusion tensor imaging (DTI): correlations with histology and behavior. Magn Reson Imaging 2015;33:95–101 doi:10.1016/j.mri.2014.09.005 pmid:25271136
    CrossRefPubMed
  33. 33.↵
    1. Yankeelov TE,
    2. Luci JJ,
    3. Lepage M, et al
    . Quantitative pharmacokinetic analysis of DCE-MRI data without an arterial input function: a reference region model. Magn Reson Imaging 2005;23:519–29 doi:10.1016/j.mri.2005.02.013 pmid:15919597
    CrossRefPubMedWeb of Science
  34. 34.↵
    1. Rohrer M,
    2. Bauer H,
    3. Mintorovitch J, et al
    . Comparison of magnetic properties of MRI contrast media solutions at different magnetic field strengths. Invest Radiol 2005;40:715–24 doi:10.1097/01.rli.0000184756.66360.d3 pmid:16230904
    CrossRefPubMedWeb of Science
PreviousNext
Back to top

In this issue

American Journal of Neuroradiology: 39 (1)
American Journal of Neuroradiology
Vol. 39, Issue 1
1 Jan 2018
  • Table of Contents
  • Index by author
  • Complete Issue (PDF)
Advertisement
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Gadolinium DTPA Enhancement Characteristics of the Rat Sciatic Nerve after Crush Injury at 4.7T
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Cite this article
B.J. Hill, K.R. Padgett, V. Kalra, A. Marcillo, B. Bowen, P. Pattany, D. Dietrich, R. Quencer
Gadolinium DTPA Enhancement Characteristics of the Rat Sciatic Nerve after Crush Injury at 4.7T
American Journal of Neuroradiology Jan 2018, 39 (1) 177-183; DOI: 10.3174/ajnr.A5437

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
0 Responses
Respond to this article
Share
Bookmark this article
Gadolinium DTPA Enhancement Characteristics of the Rat Sciatic Nerve after Crush Injury at 4.7T
B.J. Hill, K.R. Padgett, V. Kalra, A. Marcillo, B. Bowen, P. Pattany, D. Dietrich, R. Quencer
American Journal of Neuroradiology Jan 2018, 39 (1) 177-183; DOI: 10.3174/ajnr.A5437
del.icio.us logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Purchase

Jump to section

  • Article
    • Abstract
    • ABBREVIATIONS:
    • Materials and Methods
    • Results
    • Discussion
    • Conclusions
    • Acknowledgments
    • Footnotes
    • References
  • Figures & Data
  • Supplemental
  • Info & Metrics
  • Responses
  • References
  • PDF

Related Articles

  • PubMed
  • Google Scholar

Cited By...

  • Is Gd-DTPA Necessary in Clinical Practice for Peripheral Nerve Injury?
  • Crossref (14)
  • Google Scholar

This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

  • Incorporating Blood Flow in Nerve Injury and Regeneration Assessment
    Stewart Yeoh, Wesley S. Warner, Samer S. Merchant, Edward W. Hsu, Denes v. Agoston, Mark A. Mahan
    Frontiers in Surgery 2022 9
  • Magnetic Resonance Imaging as a Biomarker in Rodent Peripheral Nerve Injury Models Reveals an Age-Related Impairment of Nerve Regeneration
    Elisa Giorgetti, Michael Obrecht, Marie Ronco, Moh Panesar, Christian Lambert, Nathalie Accart, Arno Doelemeyer, Mark Nash, Michael Bidinosti, Nicolau Beckmann
    Scientific Reports 2019 9 1
  • Technical Update on MR Neurography
    Teodoro Martín-Noguerol, Paula Montesinos, Alvand Hassankhani, Dario A. Bencardino, Rafael Barousse, Antonio Luna
    Seminars in Musculoskeletal Radiology 2022 26 02
  • A Dual‐Modal Magnetic Resonance/Photoacoustic Imaging Tracer for Long‐Term High‐Precision Tracking and Facilitating Repair of Peripheral Nerve Injuries
    Jingyan Ren, Xiaoduo Tang, Tao Wang, Xin Wei, Junhu Zhang, Laijin Lu, Yang Liu, Bai Yang
    Advanced Healthcare Materials 2022 11 13
  • Combine contrast-enhanced 3D T2-weighted short inversion time inversion recovery MR neurography with MR angiography at 1.5 T in the assessment of brachial plexopathy
    Zhengdao Xu, Tonghua Zhang, Jianxin Chen, Zongbao Liu, Tao Wang, Yijiang Hu, Jiahui Zhang, Feifei Xue
    Magnetic Resonance Materials in Physics, Biology and Medicine 2021 34 2
  • Diagnostic Efficacy of 18F-FDG PET/MRI in Peripheral Nerve Injury Models
    Jung Woo Nam, Mi Jee Lee, Hyung Jun Kim
    Neurochemical Research 2019 44 9
  • MRI features of symptomatic amputation neuromas
    Bo Mi Chung, Guen Young Lee, Wan Tae Kim, Injoong Kim, Young Lee, Sung Bin Park
    European Radiology 2021 31 10
  • Comparison of MR findings of acute traumatic peripheral nerve injury and acute compressive neuropathy in a rat model
    Bo Ra Kim, Dong-Ho Ha, Jong Kuk Kim, Young Hee Kim, Xi Chen
    PLOS ONE 2020 15 11
  • Imaging and histopathologic features of reversible nerve root and peripheral nerve edema secondary to disc herniation in a cat
    Robert Herzig, Adriano Wang‐Leandro, Frank Steffen, Kaspar Matiasek, Katrin M. Beckmann
    Journal of Veterinary Internal Medicine 2021 35 3
  • New insights into the evaluation of peripheral nerves lesions: a survival guide for beginners
    Teodoro Martín-Noguerol, Rafael Barousse, Antonio Luna, Mariano Socolovsky, Juan M. Górriz, Manuel Gómez-Río
    Neuroradiology 2022 64 5

More in this TOC Section

Peripheral Nervous System

  • Dorsal Root Ganglion Volumetry by MR Gangliography
  • Role of MR Neurography for the Diagnosis of Peripheral Trigeminal Nerve Injuries in Patients with Prior Molar Tooth Extraction
  • MR Imaging of the Superior Cervical Ganglion and Inferior Ganglion of the Vagus Nerve: Structures That Can Mimic Pathologic Retropharyngeal Lymph Nodes
Show more Peripheral Nervous System

Spine

  • Bern Score Validity for SIH
  • MP2RAGE 7T in MS Lesions of the Cervical Spine
  • Deep Learning for STIR Spine MRI Quality
Show more Spine

Similar Articles

Advertisement

Indexed Content

  • Current Issue
  • Accepted Manuscripts
  • Article Preview
  • Past Issues
  • Editorials
  • Editors Choice
  • Fellow Journal Club
  • Letters to the Editor

Cases

  • Case Collection
  • Archive - Case of the Week
  • Archive - Case of the Month
  • Archive - Classic Case

Special Collections

  • Special Collections

Resources

  • News and Updates
  • Turn around Times
  • Submit a Manuscript
  • Author Policies
  • Manuscript Submission Guidelines
  • Evidence-Based Medicine Level Guide
  • Publishing Checklists
  • Graphical Abstract Preparation
  • Imaging Protocol Submission
  • Submit a Case
  • Become a Reviewer/Academy of Reviewers
  • Get Peer Review Credit from Publons

Multimedia

  • AJNR Podcast
  • AJNR SCANtastic
  • Video Articles

About Us

  • About AJNR
  • Editorial Board
  • Not an AJNR Subscriber? Join Now
  • Alerts
  • Feedback
  • Advertise with us
  • Librarian Resources
  • Permissions
  • Terms and Conditions

American Society of Neuroradiology

  • Not an ASNR Member? Join Now

© 2025 by the American Society of Neuroradiology All rights, including for text and data mining, AI training, and similar technologies, are reserved.
Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire