Article Figures & Data
Figures
- Fig 1.
The 10 representative cases of MCA aneurysms used for 3D CFD. A subset of 3 cases (A–C) was truncated differently, as depicted by A′, B′, C′. These are color-coded to identify their data in subsequent figures. Cases A and A′ highlight their individual bifurcations, as used by the splitting method.
- Fig 2.
Bland-Altman plots reveal non-negligible limits of agreement (upper and lower dotted lines) for cycle-averaged MCA flow rates computed via the different outflow strategies. Colored circles represent the 10 cases subsequently selected for 3D CFD. Note that the modified extents (cases A′, B′, C′) show non-negligible changes in flow rates for both zero-pressure and Murray-law methods. The y-axis is defined as the considered outflow method minus the splitting method flow rate, divided by the average of flow rates obtained with the 2 methods.
- Fig 3.
Comparison of 3 normalized hemodynamic indices (see “Materials and Methods”) determined from 3D CFD simulations, computed using zero-pressure-versus-splitting methods. The lower right of each panel shows the coefficients of determination (R2) as measures of correlation and agreement. The dotted line is perfect agreement. Note the triangles and different colors used to highlight the different truncations for cases A, B, and C (see symbol legend in Fig 2). These data points are translated only horizontally because the splitting method is, by design, not sensitive to model extent.
Tables
- Table 1:
For the 70 patients with MCA aneurysms, mean ± SD flow rates (mL/min) in the major arteries and mean flow divisions at the ICA terminusa
Outflow Method ACA MCA OA PcomA ACA:MCA Zero-pressure 103 ± 50 137 ± 53 15 ± 10 71 ± 42 43:57 Murray-law 89 ± 47 152 ± 57 14 ± 11 65 ± 46 37:63 Splitting 86 ± 38 154 ± 46 16 ± 8 60 ± 30 36:64 Literature values 84 ± 24 142 ± 31 11 ± 5 59 ± 14b 37:63 - Table 2:
Impact of model extent on predicted MCA flow rates (mL/min) for the 3 cases with modified outflow extents
Outflow Method A A′ B B′ C C′ Zero-pressure 97 136 134 141 49 85 Murray-law 82 195 145 113 76 90 Splitting 166 166 133 133 106 106
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