Evaluation of the Sensitivity of Inhomogeneous Magnetization Transfer (ihMT) MRI for Multiple Sclerosis

References

1. 1.↵
   2. MacKay A,
   3. Whittall K,
   4. Adler J, et al

   . In vivo visualization of myelin water in brain by magnetic resonance. Magn Reson Med 1994;31:673–77 doi:10.1002/mrm.1910310614 pmid:8057820

   CrossRefPubMedWeb of Science
2. 2.↵
   2. Henkelman RM,
   3. Stanisz GJ,
   4. Graham SJ

   . Magnetization transfer in MRI: a review. NMR Biomed 2001;14:57–64 doi:10.1002/nbm.683 pmid:11320533

   CrossRefPubMedWeb of Science
3. 3.↵
   2. Sled JG,
   3. Pike GB

   . Quantitative imaging of magnetization transfer exchange and relaxation properties in vivo using MRI. Magn Reson Med 2001;46:923–31 doi:10.1002/mrm.1278 pmid:11675644

   CrossRefPubMedWeb of Science
4. 4.↵
   2. Gass A,
   3. Barker GJ,
   4. Kidd D, et al

   . Correlation of magnetization transfer ratio with clinical disability in multiple sclerosis. Ann Neurol 1994;36:62–67 doi:10.1002/ana.410360113 pmid:8024264

   CrossRefPubMedWeb of Science
5. 5.↵
   2. Rocca MA,
   3. Mastronardo G,
   4. Rodegher M, et al

   . Long-term changes of magnetization transfer–derived measures from patients with relapsing-remitting and secondary progressive multiple sclerosis. AJNR Am J Neuroradiol 1999;20:821–27 pmid:10369352

   Abstract/FREE Full Text
6. 6.↵
   2. Schmierer K,
   3. Scaravilli F,
   4. Altmann DR, et al

   . Magnetization transfer ratio and myelin in postmortem multiple sclerosis brain. Ann Neurol 2004;56:407–15 doi:10.1002/ana.20202 pmid:15349868

   CrossRefPubMedWeb of Science
7. 7.↵
   2. Filippi M,
   3. Campi A,
   4. Dousset V, et al

   . A magnetization transfer imaging study of normal-appearing white matter in multiple sclerosis. Neurology 1995;45(3 Pt 1):478–82 doi:10.1212/WNL.45.3.478 pmid:7898700

   Abstract/FREE Full Text
8. 8.↵
   2. Varma G,
   3. Duhamel G,
   4. de Bazelaire C, et al

   . Magnetization transfer from inhomogeneously broadened lines: a potential marker for myelin. Magn Reson Med 2015;73:614–22 doi:10.1002/mrm.25174 pmid:24604578

   CrossRefPubMed
9. 9.↵
   2. Varma G,
   3. Girard OM,
   4. Prevost VH, et al

   . Interpretation of magnetization transfer from inhomogeneously broadened lines (ihMT) in tissues as a dipolar order effect within motion restricted molecules. J Magn Reson 2015;260:67–76 doi:10.1016/j.jmr.2015.08.024 pmid:26408956

   CrossRefPubMed
10. 10.↵
    2. Swanson SD,
    3. Malyarenko DI,
    4. Fabiilli ML, et al

    . Molecular, dynamic, and structural origin of inhomogeneous magnetization transfer in lipid membranes. Magn Reson Med 2017;77:1318–28 doi:10.1002/mrm.26210 pmid:27029318

    CrossRefPubMed
11. 11.↵
    2. Manning AP,
    3. Chang KL,
    4. MacKay AL, et al

    . The physical mechanism of “inhomogeneous” magnetization transfer MRI. J Magn Reson 2017;274:125–36 doi:10.1016/j.jmr.2016.11.013 pmid:27918896

    CrossRefPubMed
12. 12.↵
    2. Varma G,
    3. Girard OM,
    4. Prevost VH, et al

    . In vivo measurement of a new source of contrast, the dipolar relaxation time, T_1D, using a modified inhomogeneous magnetization transfer (ihMT) sequence. Magn Reson Med 2017;78:1362–72 doi:10.1002/mrm.26523 pmid:27859618

    CrossRefPubMed
13. 13.↵
    2. Prevost VH,
    3. Girard OM,
    4. Mchinda S, et al

    . Optimization of inhomogeneous magnetization transfer (ihMT) MRI contrast for preclinical studies using dipolar relaxation time (T_1D) filtering. NMR Biomed 2017;30:e3706 doi:10.1002/nbm.3706

    CrossRef
14. 14.↵
    2. Prevost VH,
    3. Girard OM,
    4. Cayre M, et al

    . Validation of inhomogeneous magnetization transfer (ihMT) as a myelin biomarker. In: Proceedings of the Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine, Honolulu, Hawaii. April 22–24, 2017:1498
15. 15.↵
    2. Girard OM,
    3. Prevost VH,
    4. Varma G, et al

    . Magnetization transfer from inhomogeneously broadened lines (ihMT): experimental optimization of saturation parameters for human brain imaging at 1.5 Tesla. Magn Reson Med 2015;73:2111–21 doi:10.1002/mrm.25330 pmid:24962257

    CrossRefPubMed
16. 16.↵
    2. Girard OM,
    3. Callot V,
    4. Prevost VH, et al

    . Magnetization transfer from inhomogeneously broadened lines (ihMT): improved imaging strategy for spinal cord applications. Magn Reson Med 2017;77:581–91 doi:10.1002/mrm.26134 pmid:26959278

    CrossRefPubMed
17. 17.↵
    2. Kurtzke JF

    . Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS). Neurology 1983;33:1444–52 doi:10.1212/WNL.33.11.1444 pmid:6685237

    Abstract/FREE Full Text
18. 18.↵
    2. Prevost VH,
    3. Girard OM,
    4. Varma G, et al

    . Minimizing the effects of magnetization transfer asymmetry on inhomogeneous magnetization transfer (ihMT) at ultra-high magnetic field (11.75 T). MAGMA 2016;29:699–709 doi:10.1007/s10334-015-0523-2 pmid:26762244

    CrossRefPubMed
19. 19.↵
    2. Avants BB,
    3. Tustison NJ,
    4. Song G, et al

    . A reproducible evaluation of ANTs similarity metric performance in brain image registration. Neuroimage 2011;54:2033–44 doi:10.1016/j.neuroimage.2010.09.025 pmid:20851191

    CrossRefPubMed
20. 20.↵
    1. Liang H,
    2. Bronzino JD,
    3. Peterson DR

    2. Wu G,
    3. Jia H,
    4. Wang Q, et al

    . Emergence of groupwise registration in MR brain study. In: Liang H, Bronzino JD, Peterson DR, eds. Biosignal Processing: Principles and Practices. Boca Raton, Florida: CRC Press; 2012: chap 5
21. 21.↵
    2. Neuhäuser M,
    3. Bretz F

    . Nonparametric all-pairs multiple comparisons. Biom J 2001;43:571–80

    CrossRefWeb of Science
22. 22.↵
    2. Filippi M,
    3. Agosta F

    . Magnetization transfer MRI in multiple sclerosis. J Neuroimaging 2007;17:22S–26S. doi:10.1111/j.1552-6569.2007.00132.x pmid:17425730

    CrossRefPubMedWeb of Science
23. 23.↵
    2. Traboulsee A,
    3. Dehmeshki J,
    4. Peters KR, et al

    . Disability in multiple sclerosis is related to normal appearing brain tissue MTR histogram abnormalities. Mult Scler 2003;9:566–73 doi:10.1191/1352458503ms958oa pmid:14664468

    CrossRefPubMedWeb of Science
24. 24.↵
    2. Vrenken H,
    3. Pouwels PJ,
    4. Ropele S, et al

    . Magnetization transfer ratio measurement in multiple sclerosis normal-appearing brain tissue: limited differences with controls but relationships with clinical and MR measures of disease. Mult Scler 2007;13:708–16 doi:10.1177/1352458506075521 pmid:17613597

    CrossRefPubMed
25. 25.↵
    2. Amann M,
    3. Papadopoulou A,
    4. Andelova M, et al

    . Magnetization transfer ratio in lesions rather than normal-appearing brain relates to disability in patients with multiple sclerosis. J Neurol 2015;262:1909–17 doi:10.1007/s00415-015-7793-5 pmid:26041614

    CrossRefPubMed
26. 26.↵
    2. De Stefano N

    . Brain damage as detected by magnetization transfer imaging is less pronounced in benign than in early relapsing multiple sclerosis. Brain 2006;129:2008–16 doi:10.1093/brain/awl152 pmid:16815879

    CrossRefPubMedWeb of Science
27. 27.↵
    2. Santos AC,
    3. Narayanan S,
    4. de Stefano N, et al

    . Magnetization transfer can predict clinical evolution in patients with multiple sclerosis. J Neurol 2002;249:662–68 doi:10.1007/s00415-002-0686-4 pmid:12111296

    CrossRefPubMedWeb of Science
28. 28.↵
    2. Moll NM,
    3. Rietsch AM,
    4. Thomas S, et al

    . Multiple sclerosis normal-appearing white matter: pathology-imaging correlations. Ann Neurol 2011;70:764–73 doi:10.1002/ana.22521 pmid:22162059

    CrossRefPubMed
29. 29.↵
    2. Mchinda S,
    3. Varma G,
    4. Prevost VH, et al

    . Whole brain inhomogeneous magnetization transfer (ihMT) imaging: sensitivity enhancement within a steady-state gradient echo sequence. Magn Reson Med 2017 Sep 23. [Epub ahead of print] doi:10.1002/mrm.26907 pmid:28940355

    CrossRefPubMed