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Research ArticleSpine

Zonally Magnified Oblique Multislice and Non-Zonally Magnified Oblique Multislice DWI of the Cervical Spinal Cord

M. Alizadeh, M.M. Poplawski, J. Fisher, R.J.T. Gorniak, A. Dresner, F.B. Mohamed and A.E. Flanders
American Journal of Neuroradiology August 2018, 39 (8) 1555-1561; DOI: https://doi.org/10.3174/ajnr.A5703
M. Alizadeh
aFrom the Department of Radiology (M.A., M.M.P., J.F., R.J.T.G., A.D., F.B.M., A.E.F.), Jefferson Integrated Magnetic Resonance Imaging Center
bDepartment of Neurosurgery (M.A.), Thomas Jefferson University, Philadelphia, Pennsylvania.
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M.M. Poplawski
aFrom the Department of Radiology (M.A., M.M.P., J.F., R.J.T.G., A.D., F.B.M., A.E.F.), Jefferson Integrated Magnetic Resonance Imaging Center
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J. Fisher
aFrom the Department of Radiology (M.A., M.M.P., J.F., R.J.T.G., A.D., F.B.M., A.E.F.), Jefferson Integrated Magnetic Resonance Imaging Center
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R.J.T. Gorniak
aFrom the Department of Radiology (M.A., M.M.P., J.F., R.J.T.G., A.D., F.B.M., A.E.F.), Jefferson Integrated Magnetic Resonance Imaging Center
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A. Dresner
aFrom the Department of Radiology (M.A., M.M.P., J.F., R.J.T.G., A.D., F.B.M., A.E.F.), Jefferson Integrated Magnetic Resonance Imaging Center
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F.B. Mohamed
aFrom the Department of Radiology (M.A., M.M.P., J.F., R.J.T.G., A.D., F.B.M., A.E.F.), Jefferson Integrated Magnetic Resonance Imaging Center
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A.E. Flanders
aFrom the Department of Radiology (M.A., M.M.P., J.F., R.J.T.G., A.D., F.B.M., A.E.F.), Jefferson Integrated Magnetic Resonance Imaging Center
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    Fig 1.

    The size of ROIs manually drawn at each intervertebral disc level. The error bars represent the SDs.

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    Fig 2.

    Averaged DTI parameters of ZOOM and non-ZOOM (full-FOV [fFOV] single-shot-EPI [ss-EPI]) sequences for the direct age-matched group as a function of intervertebral disc levels across all subjects. The error bars represent the SDs.

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    Fig 3.

    Averaged DTI indices of ZOOM EPI and non-ZOOM (full-FOV [fFOV] single-shot-EPI) sequences for the indirect age-matched group as a function of intervertebral disc levels across all subjects. The error bars represent the SDs.

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    Fig 4.

    Illustration of DTI indices at different spinal cord levels localized by a T2-weighted image in ZOOM. Midsagittal T2-weighted image shows the location of the 7 axial diffusion tensor images that cover the entire length of the cervical spinal cord. Color and gray-scale FA maps are in the first and second columns. MD, AD, and RD maps at each location are also shown. Note that spatial resolution is improved and distortion is lower compared with the non-ZOOM acquisition (Fig 5). ssEPI indicates single-shot EPI.

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    Fig 5.

    Illustration of DTI indices at different spinal cord levels localized by a T2-weighted image in non-ZOOM. Midsagittal T2-weighted image shows the location of the 7 axial diffusion tensor images that cover the entire length of the cervical spinal cord. Color and gray-scale FA maps are in the first and second columns. MD, AD, and RD maps at each location are also shown.

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    Table 1:

    Comparison of non-ZOOM and ZOOM of averaged FA, MD, AD, and RD values along the cervical spinal cord levels and across direct age-matched subjectsa

    Non-ZOOMZOOMProb<|t|
    FA0.65 ± 0.0420.74 ± 0.038P = .04
    MD0.72 ± 0.0380.50 ± 0.032P = 005
    AD1.36 ± 0.0860.99 ± 0.021P = .002
    RD0.42 ± 0.0410.24 ± 0.037P < .001
    • Note:—Prob<|t| indicates the P value for 2-tailed test.

    • ↵a Data are means and SDs.

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    Table 2:

    Comparison of non-ZOOM and ZOOM of averaged FA, MD, AD, and RD values along the cervical spinal cord levels and across indirect age-matched subjectsa

    Non-ZOOMZOOMProb<|t|
    FA0.65 ± 0.0670.76 ± 0.04P = .03
    MD0.7 ± 0.0380.49 ± 0.047P = .002
    AD1.3 ± 0.061.02 ± 0.05P < .001
    RD0.4 ± 0.060.23 ± 0.05P = .002
    • ↵a Data are means and SDs.

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American Journal of Neuroradiology: 39 (8)
American Journal of Neuroradiology
Vol. 39, Issue 8
1 Aug 2018
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Cite this article
M. Alizadeh, M.M. Poplawski, J. Fisher, R.J.T. Gorniak, A. Dresner, F.B. Mohamed, A.E. Flanders
Zonally Magnified Oblique Multislice and Non-Zonally Magnified Oblique Multislice DWI of the Cervical Spinal Cord
American Journal of Neuroradiology Aug 2018, 39 (8) 1555-1561; DOI: 10.3174/ajnr.A5703

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Zonally Magnified Oblique Multislice and Non-Zonally Magnified Oblique Multislice DWI of the Cervical Spinal Cord
M. Alizadeh, M.M. Poplawski, J. Fisher, R.J.T. Gorniak, A. Dresner, F.B. Mohamed, A.E. Flanders
American Journal of Neuroradiology Aug 2018, 39 (8) 1555-1561; DOI: 10.3174/ajnr.A5703
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