Index by author

The authors performed a retrospective review of 48 patients with cerebral metastases from June 2016 to October 2017. Brain MRIs included gadolinium-enhanced T1-weighted IR-FSPGR-BRAVO and CUBE, with subsequent generation of nonoverlapping CUBE MIP and overlapping CUBE MIP. Two blinded radiologists identified the total number and location of metastases on each image type. This study suggests that the use of overlapping CUBE MIP or nonoverlapping CUBE MIP for the detection of brain metastases can reduce interpretation time without sacrificing sensitivity, though the contrast-to-noise ratio of lesions is highest for overlapping CUBE MIP.

The authors automated the identification of enlarged perivascular spaces in brain MR images using a custom quantitative program designed with Matlab. They quantified the densities of enlarged perivascular spaces for patients with mild cognitive impairment (n=14) and age-matched cognitively healthy controls (n=15) and compared them to determine whether the density of enlarged perivascular spaces can serve as an imaging surrogate for mild cognitive impairment diagnosis. The density of enlarged perivascular spaces was found to be significantly higher in those with mild cognitive impairment compared with age-matched healthy control subjects.