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Research ArticleNeurointervention

Feasibility, Safety, and Periprocedural Complications Associated with Endovascular Treatment of Ruptured Intracranial Aneurysms according to the Depth of Anesthesia

J. Song, C.-Y. Lee and H.-W. Kim
American Journal of Neuroradiology September 2018, 39 (9) 1676-1681; DOI: https://doi.org/10.3174/ajnr.A5753
J. Song
aFrom the Department of Neurosurgery, College of Medicine, Konyang University Hospital, Konyang University Myunggok Medical Research Institute, Daejeon, Republic of Korea.
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C.-Y. Lee
aFrom the Department of Neurosurgery, College of Medicine, Konyang University Hospital, Konyang University Myunggok Medical Research Institute, Daejeon, Republic of Korea.
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H.-W. Kim
aFrom the Department of Neurosurgery, College of Medicine, Konyang University Hospital, Konyang University Myunggok Medical Research Institute, Daejeon, Republic of Korea.
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    Fig 1.

    Rigid and radiolucent head holder.

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    Fig 2.

    Distribution of patients according to clinical grade and depth of anesthesia.

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    Fig 3.

    Procedure-related complications according to clinical grade and depth of anesthesia. Note:—( ) indicates number of patients.

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    Table 1:

    Continuum of depth of sedation—definition of general anesthesia and levels of sedation/analgesia

    Minimal Sedation/ AnxiolysisModerate Sedation/Analgesia (Conscious Sedation)Deep Sedation AnalgesiaGeneral Anesthesia
    ResponsivenessNormal response to verbal stimulationPurposefula response to verbal or tactile stimulationPurposefula response after repeat or painful stimulationUnarousable even with painful stimulus
    AirwayUnaffectedNo intervention requiredIntervention may be requiredIntervention often required
    Spontaneous ventilationUnaffectedAdequateMay be inadequateFrequently inadequate
    Cardiovascular functionUnaffectedUsually maintainedUsually maintainedMay be impaired
    • ↵a Reflex withdrawal from a painful stimulus is not considered a purposeful response.

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    Table 2:

    Baseline demographic data

    VariableNo.
    No. of aneurysms183
    No. of patients183
    Age (mean) (SD) (yr)60.2 (14.8)
        Younger than 4013 (7.1%)
        40–5044 (24.0%)
        50–6043 (23.5%)
        60–7026 (14.2%)
        70–8040 (21.9%)
        Older than 8017 (9.3%)
    Sex
        Female129 (70.5%)
        Male54 (29.5%)
    Multiplicity31 (16.9%)
    Location
        ACA80 (43.7%)
        ICA56 (30.6%)
        MCA31 (16.9%)
        VB15 (8.2%)
    Aneurysm size (mm)
        ≤568 (39.9%)
        5–1092 (47.5%)
        10–1521 (11.5%)
        >152 (1.1%)
    Modalities of EVT
        Simple catheter114 (62.3%)
        Double catheter47 (25.7%)
        Stent-assisted22 (12.0%)
    Anesthesia grade
        Local anesthesia70 (38.3%)
        Conscious sedation33 (18.0%)
        Deep sedation78 (42.6%)
        General anesthesia2 (1.1%)
    Hunt and Hess scale grade
        140 (21.9%)
        257 (31.1%)
        322 (12.0%)
        430 (16.4%)
        534 (18.6%)
    • Note:—ACA indicates anterior cerebral artery; VB, vertebrobasilar artery.

    • View popup
    Table 3:

    Statistical analysis of complications with related factors

    AllEVT (Complications, n = 16)
    HemorrhagicThromboembolicP Value
    Age (yr).399
        Younger than 40523
        40–50303
        50–60523
        60–70312
        Older than 70312
    Sex
        Female1147.9026
    Location.6297
        ICA624
        ACA321
        MCA514
        VB202
    Aneurysm size (n = 1230) (mm).3012
        ≤5431
        5–101129
        10–15101
        >15000
    Modalities of EVT.3919
        Simple catheter725
        Double catheter624
        Stent-assisted312
    Anesthesia grade.3307
        Local anesthesia413
        Conscious sedation532
        Deep sedation716
        General anesthesia000
    Hunt and Hess grade.0731
        1101
        2505
        3312
        4330
        5413
        Good (1 or 2)606.05438
        Poor (3, 4, or 5)1055
    • Note:—ACA indicates anterior cerebral artery; VB, vertebrobasilar artery.

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American Journal of Neuroradiology: 39 (9)
American Journal of Neuroradiology
Vol. 39, Issue 9
1 Sep 2018
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Cite this article
J. Song, C.-Y. Lee, H.-W. Kim
Feasibility, Safety, and Periprocedural Complications Associated with Endovascular Treatment of Ruptured Intracranial Aneurysms according to the Depth of Anesthesia
American Journal of Neuroradiology Sep 2018, 39 (9) 1676-1681; DOI: 10.3174/ajnr.A5753

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Feasibility, Safety, and Periprocedural Complications Associated with Endovascular Treatment of Ruptured Intracranial Aneurysms according to the Depth of Anesthesia
J. Song, C.-Y. Lee, H.-W. Kim
American Journal of Neuroradiology Sep 2018, 39 (9) 1676-1681; DOI: 10.3174/ajnr.A5753
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