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Research ArticleNeurointervention

Coil Embolization in Patients with Recurrent Cerebral Aneurysms Who Previously Underwent Surgical Clipping

S.-T. Kim, J.W. Baek, S.-C. Jin, J.H. Park, J.S. Kim, H.Y. Kim, H.W. Jeong and Y.G. Jeong
American Journal of Neuroradiology January 2019, 40 (1) 116-121; DOI: https://doi.org/10.3174/ajnr.A5909
S.-T. Kim
aFrom the Departments of Neurosurgery (S.-T.K., J.H.P., Y.G.J.)
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J.W. Baek
bDiagnostic Radiology (J.W.B., H.W.J.), Busan Paik Hospital, Inje University, College of Medicine, Busan, Republic of Korea
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S.-C. Jin
cDepartment of Neurosurgery (S.-C.J., J.S.K., H.Y.K.), Haeundae Paik Hospital, Inje University, College of Medicine, Busan, Republic of Korea.
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J.H. Park
aFrom the Departments of Neurosurgery (S.-T.K., J.H.P., Y.G.J.)
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J.S. Kim
cDepartment of Neurosurgery (S.-C.J., J.S.K., H.Y.K.), Haeundae Paik Hospital, Inje University, College of Medicine, Busan, Republic of Korea.
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H.Y. Kim
cDepartment of Neurosurgery (S.-C.J., J.S.K., H.Y.K.), Haeundae Paik Hospital, Inje University, College of Medicine, Busan, Republic of Korea.
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H.W. Jeong
bDiagnostic Radiology (J.W.B., H.W.J.), Busan Paik Hospital, Inje University, College of Medicine, Busan, Republic of Korea
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Y.G. Jeong
aFrom the Departments of Neurosurgery (S.-T.K., J.H.P., Y.G.J.)
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  • Fig 1.
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    Fig 1.

    First case of our series, posterior communicating artery aneurysm. A, Working angle view angiography before the first coil embolization. B, After the first coil embolization, the final angiography evaluation reveals complete occlusion of the aneurysm. C, After 41 months, follow-up angiography reveals major recurrence of the aneurysm. D, After the second coil embolization, the residual neck is detected in the final angiography evaluation. E, After 43 months, follow-up angiography reveals major recurrence. F, Final image of the third coil embolization.

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    Fig 2.

    Eighth case of our series, basilar tip aneurysm. A, Working angle view angiography before first coil embolization. B, After the first coil embolization, the final angiography evaluation reveals complete occlusion of the aneurysm. C, After 29 months, follow-up angiography reveals major recurrence of the aneurysm. D, After the second coil embolization, the residual neck is detected in the final angiography evaluation. E, Follow-up angiography reveals minor recurrence.

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    Fig 3.

    Thirteenth case in our series, left middle cerebral artery bifurcation aneurysm. The first coil embolization of this aneurysm was performed at another hospital. Therefore, we confirmed the presence of a residual neck in the medical record, without imaging. A, At 180 months after the first coil embolization, 3D rotational angiography reveals recurrence of a middle cerebral artery bifurcation aneurysm. B, Working angle angiography before the second coil embolization. C, The final angiography evaluation reveals complete occlusion of the aneurysm.

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    Fig 4.

    Fourteenth case of our series, posterior communicating artery aneurysm. A, Working angle view angiography before the first coil embolization. B, After the first coil embolization, the final angiography evaluation reveals the residual neck of the aneurysm. C, After 18 months, follow-up angiography reveals major recurrence of the aneurysm. D, After the second coil embolization, a residual neck is detected in the final angiography evaluation. E, Follow-up angiography reveals minor recurrence.

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    Fig 5.

    Sixteenth case of our series, posterior communicating artery aneurysm. A, Working angle view angiography before the first coil embolization. B, After the first coil embolization, the final angiographic evaluation reveals the residual neck of the aneurysm. C, After 47 months, follow-up angiography reveals major recurrence of the aneurysm. D, After the second coil embolization, the final angiography evaluation reveals complete occlusion of the aneurysm.

Tables

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    Table 1:

    Factors related to major recurrence in univariate analysis

    VariablesCategoriesMajor RecurrenceP Valuea
    AgeYounger than 60 yr (n = 7)4 (57.1%).293
    60 yr or older (n = 5)1 (20.0%)
    SexMale (n = 4)2 (50.0%)1.0
    Female (n = 8)3 (37.5%)
    Presentation at surgeryRuptured (n = 12)5 (41.7%)1.0
    Unruptured (n = 0)0 (0%)
    Presentation at coilingRuptured (n = 6)4 (66.7%).242
    Unruptured (n = 6)1 (16.7%)
    Multiple aneurysmsYes (n = 6)2 (33.3%)1.0
    No (n = 6)3 (50.0%)
    Size≤10 mm (n = 11)4 (36.4%).417
    >10 mm (n = 1)1 (100%)
    Wide neckNarrow (n = 2)0 (0%).470
    Wide (n = 10)5 (50.0%)
    Stent useYes (n = 1)0 (0%)1.0
    No (n = 11)5 (45.5%)
    Procedural complicationsYes (n = 1)1 (100%).417
    No (n = 11)4 (36.4%)
    Clinical outcome (good, mRS ≤ 2)Good (n = 9)3 (33.3%).523
    Bad (n = 3)2 (66.7%)
    Rebleeding after coilingYes (n = 2)2 (100%).152
    No (n = 10)3 (30.0%)
    Immediate radiologic resultsComplete (n = 8)3 (20%)1.0
    Remnant neck (n = 4)2 (37.5%)
    Remnant sac (n = 0)–
    • Note:—mRS indicates modified Rankin scale.

    • ↵a All P values are significant.

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    Table 2:

    Characteristics and treatment results of recurrent aneurysms after coil embolization

    No.LocationPresentation at ClippingPresentation at CoilingInterval to RetreatmentSize (H × W) (mm)Neck Diameter (mm)Immediate Radiologic ResultsReason for RecurrenceFollow-Up mRS
    1PcomARR/-/-41/43 mo8.7 × 6.35.1C/N/NRegrowth2
    8Basilar tipR-/-29 mo3.8 × 7.26C/NRegrowth0
    13MCARR/R180 mo12 × 1010N/CRegrowth6
    14PcomARR/R18 mo7.8 × 8.18.1N/NRegrowth4
    16PcomARR/-47 mo3.3 × 3.02.4N/CRegrowth0
    • Note:—C indicates complete occlusion; H, height; N, residual neck; R, ruptured; W, width.

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American Journal of Neuroradiology: 40 (1)
American Journal of Neuroradiology
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1 Jan 2019
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Cite this article
S.-T. Kim, J.W. Baek, S.-C. Jin, J.H. Park, J.S. Kim, H.Y. Kim, H.W. Jeong, Y.G. Jeong
Coil Embolization in Patients with Recurrent Cerebral Aneurysms Who Previously Underwent Surgical Clipping
American Journal of Neuroradiology Jan 2019, 40 (1) 116-121; DOI: 10.3174/ajnr.A5909

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Coil Embolization in Patients with Recurrent Cerebral Aneurysms Who Previously Underwent Surgical Clipping
S.-T. Kim, J.W. Baek, S.-C. Jin, J.H. Park, J.S. Kim, H.Y. Kim, H.W. Jeong, Y.G. Jeong
American Journal of Neuroradiology Jan 2019, 40 (1) 116-121; DOI: 10.3174/ajnr.A5909
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