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AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Research ArticleAdult Brain

Defining the Normal Dorsal Contour of the Corpus Callosum with Time

K.L. Krause, D. Howard, D.R. Pettersson, S. Elstrott, D. Ross, J.T. Obayashi, R. Barajas, A. Bonde and J.M. Pollock
American Journal of Neuroradiology January 2019, 40 (1) 86-91; DOI: https://doi.org/10.3174/ajnr.A5886
K.L. Krause
bNeurological Surgery (K.L.K., D.R., J.T.O.), Oregon Health & Science University, Portland, Oregon.
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  • ORCID record for K.L. Krause
D. Howard
aFrom the Departments of Radiology (D.H., D.R.P., S.E., R.B., A.B., J.M.P.)
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D.R. Pettersson
aFrom the Departments of Radiology (D.H., D.R.P., S.E., R.B., A.B., J.M.P.)
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S. Elstrott
aFrom the Departments of Radiology (D.H., D.R.P., S.E., R.B., A.B., J.M.P.)
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D. Ross
bNeurological Surgery (K.L.K., D.R., J.T.O.), Oregon Health & Science University, Portland, Oregon.
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J.T. Obayashi
bNeurological Surgery (K.L.K., D.R., J.T.O.), Oregon Health & Science University, Portland, Oregon.
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R. Barajas Jr
aFrom the Departments of Radiology (D.H., D.R.P., S.E., R.B., A.B., J.M.P.)
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A. Bonde
aFrom the Departments of Radiology (D.H., D.R.P., S.E., R.B., A.B., J.M.P.)
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J.M. Pollock
aFrom the Departments of Radiology (D.H., D.R.P., S.E., R.B., A.B., J.M.P.)
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    Fig 1.

    A, Midline sagittal T1-weighted image shows an example of a normal corpus callosum without evidence of anterior or posterior notching. B, A “notch” was defined as a depression in the dorsal surface whose depth was at least 1 mm from a tangential (dashed) line to the surface of the CC. The solid arrow line shows a 3-mm-deep anterior notch. C, Three areas of notching indicated by the white arrows correspond to an undulating configuration. D, Midline sagittal T1-weighted image shows that a 3-mm anterior notch (arrow) is present. The flow void from the pericallosal artery is visualized extending into the notch (arrowhead).

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    Fig 2.

    Scatterplot of prevalence versus age in 5-year increments. The posterior notch prevalence (red squares and red line) decreases with time, R2 = 0.29. The anterior notch prevalence (blue diamonds and blue line) increases with time, R2 = 0.60. The undulating pattern prevalence (green triangles and green line) also increases with time, R2 = 0.28.

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    Fig 3.

    Scatterplot of notch depth (millimeters) versus age. No significant difference is seen in the depth of the posterior notch with increasing age (R2 = 0.01). There is a significant increase in the depth of the anterior notch with increasing age (R2 = 0.39).

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  • Retrospective review summary of brain MR imaging studies, notch count, and position

    Review Summary
    Brain MR imaging studies reviewed (No.)1639
    Brain MR imaging studies, with notches (No.)823
    Notches identified in 823 MR imaging studies (No.)1102
    Female (No.) (%)919; 56
        Notch identified460; 50
    Male (No.) (%)720; 44
        Notch identified363; 50
    Anterior position (No.) (%)344; 31
    Posterior position (No.) (%)660; 60
    Undulating, >2 notches (No.) (%)98; 9
    Pericallosal artery notch association (No.) (%)490; 60
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American Journal of Neuroradiology: 40 (1)
American Journal of Neuroradiology
Vol. 40, Issue 1
1 Jan 2019
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K.L. Krause, D. Howard, D.R. Pettersson, S. Elstrott, D. Ross, J.T. Obayashi, R. Barajas, A. Bonde, J.M. Pollock
Defining the Normal Dorsal Contour of the Corpus Callosum with Time
American Journal of Neuroradiology Jan 2019, 40 (1) 86-91; DOI: 10.3174/ajnr.A5886

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Defining the Normal Dorsal Contour of the Corpus Callosum with Time
K.L. Krause, D. Howard, D.R. Pettersson, S. Elstrott, D. Ross, J.T. Obayashi, R. Barajas, A. Bonde, J.M. Pollock
American Journal of Neuroradiology Jan 2019, 40 (1) 86-91; DOI: 10.3174/ajnr.A5886
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