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Research ArticleAdult Brain
Open Access

Disorder in Pixel-Level Edge Directions on T1WI Is Associated with the Degree of Radiation Necrosis in Primary and Metastatic Brain Tumors: Preliminary Findings

P. Prasanna, L. Rogers, T.C. Lam, M. Cohen, A. Siddalingappa, L. Wolansky, M. Pinho, A. Gupta, K.J. Hatanpaa, A. Madabhushi and P. Tiwari
American Journal of Neuroradiology March 2019, 40 (3) 412-417; DOI: https://doi.org/10.3174/ajnr.A5958
P. Prasanna
aFrom the Department of Biomedical Engineering (P.P., A.M., P.T.), Case Western Reserve University, Cleveland, Ohio
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L. Rogers
bUniversity Hospitals Case Medical Center (L.R., M.C., A.S., L.W., A.G.), Case Western Reserve School of Medicine, Cleveland, Ohio
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T.C. Lam
cTuen Mun Hospital (T.C.L.), Tuen Mun, Hong Kong
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M. Cohen
bUniversity Hospitals Case Medical Center (L.R., M.C., A.S., L.W., A.G.), Case Western Reserve School of Medicine, Cleveland, Ohio
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A. Siddalingappa
bUniversity Hospitals Case Medical Center (L.R., M.C., A.S., L.W., A.G.), Case Western Reserve School of Medicine, Cleveland, Ohio
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L. Wolansky
bUniversity Hospitals Case Medical Center (L.R., M.C., A.S., L.W., A.G.), Case Western Reserve School of Medicine, Cleveland, Ohio
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M. Pinho
dUniversity of Texas Southwestern Medical Center (M.P., K.J.H.), Dallas, Texas.
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A. Gupta
bUniversity Hospitals Case Medical Center (L.R., M.C., A.S., L.W., A.G.), Case Western Reserve School of Medicine, Cleveland, Ohio
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K.J. Hatanpaa
dUniversity of Texas Southwestern Medical Center (M.P., K.J.H.), Dallas, Texas.
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A. Madabhushi
aFrom the Department of Biomedical Engineering (P.P., A.M., P.T.), Case Western Reserve University, Cleveland, Ohio
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P. Tiwari
aFrom the Department of Biomedical Engineering (P.P., A.M., P.T.), Case Western Reserve University, Cleveland, Ohio
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Article Information

vol. 40 no. 3 412-417
DOI 
https://doi.org/10.3174/ajnr.A5958
PubMed 
30733252

Published By 
American Journal of Neuroradiology
Print ISSN 
0195-6108
Online ISSN 
1936-959X
History 
  • Received June 26, 2018
  • Accepted after revision December 13, 2018
  • Published online March 14, 2019.

Copyright & Usage 
© 2019 by American Journal of Neuroradiology Indicates open access to non-subscribers at www.ajnr.org

Author Information

  1. P. Prasannaa,
  2. L. Rogersb,
  3. T.C. Lamc,
  4. M. Cohenb,
  5. A. Siddalingappab,
  6. L. Wolanskyb,
  7. M. Pinhod,
  8. A. Guptab,
  9. K.J. Hatanpaad,
  10. A. Madabhushia and
  11. P. Tiwaria
  1. aFrom the Department of Biomedical Engineering (P.P., A.M., P.T.), Case Western Reserve University, Cleveland, Ohio
  2. bUniversity Hospitals Case Medical Center (L.R., M.C., A.S., L.W., A.G.), Case Western Reserve School of Medicine, Cleveland, Ohio
  3. cTuen Mun Hospital (T.C.L.), Tuen Mun, Hong Kong
  4. dUniversity of Texas Southwestern Medical Center (M.P., K.J.H.), Dallas, Texas.
  1. Please address correspondence to Prateek Prasanna, PhD, Research Associate, Department of Biomedical Engineering, Case Western University, 10900 Euclid Ave, Cleveland OH 44106; e-mail: prateek{at}case.edu
View Full Text

Funding

  • National Institute of Diabetes and Digestive and Kidney Diseases

    R01DK098503-02
  • DOD Prostate Cancer Synergistic Idea Development Award

    PC120857
  • DOD Lung Cancer Idea Development New Investigator Award

    LC130463
  • NIH

    1U24CA199374-01, R21CA179327-01; R21CA195152-01
  • DOD Prostate Cancer Idea Development Award

  • Case Comprehensive Cancer Center Pilot Grant VelaSano Grant from the Cleveland Clinic

  • Wallace H. Coulter Foundation Program in the Department of Biomedical Engineering at Case Western Reserve University

Altmetrics

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  • Radiomics and Radiogenomics in Neuro-Oncology
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P. Prasanna, L. Rogers, T.C. Lam, M. Cohen, A. Siddalingappa, L. Wolansky, M. Pinho, A. Gupta, K.J. Hatanpaa, A. Madabhushi, P. Tiwari
Disorder in Pixel-Level Edge Directions on T1WI Is Associated with the Degree of Radiation Necrosis in Primary and Metastatic Brain Tumors: Preliminary Findings
American Journal of Neuroradiology Mar 2019, 40 (3) 412-417; DOI: 10.3174/ajnr.A5958

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Disorder in Pixel-Level Edge Directions on T1WI Is Associated with the Degree of Radiation Necrosis in Primary and Metastatic Brain Tumors: Preliminary Findings
P. Prasanna, L. Rogers, T.C. Lam, M. Cohen, A. Siddalingappa, L. Wolansky, M. Pinho, A. Gupta, K.J. Hatanpaa, A. Madabhushi, P. Tiwari
American Journal of Neuroradiology Mar 2019, 40 (3) 412-417; DOI: 10.3174/ajnr.A5958
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This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

  • Histopathology‐validated machine learning radiographic biomarker for noninvasive discrimination between true progression and pseudo‐progression in glioblastoma
    Hamed Akbari, Saima Rathore, Spyridon Bakas, MacLean P. Nasrallah, Gaurav Shukla, Elizabeth Mamourian, Martin Rozycki, Stephen J. Bagley, Jeffrey D. Rudie, Adam E. Flanders, Adam P. Dicker, Arati S. Desai, Donald M. O’Rourke, Steven Brem, Robert Lustig, Suyash Mohan, Ronald L. Wolf, Michel Bilello, Maria Martinez‐Lage, Christos Davatzikos
    Cancer 2020 126 11
  • Current Advances and Challenges in Radiomics of Brain Tumors
    Zhenjie Yi, Lifu Long, Yu Zeng, Zhixiong Liu
    Frontiers in Oncology 2021 11
  • Chemical Exchange Saturation Transfer MRI for Differentiating Radiation Necrosis From Tumor Progression in Brain Metastasis—Application in a Clinical Setting
    Hatef Mehrabian, Rachel W. Chan, Arjun Sahgal, Hanbo Chen, Aimee Theriault, Wilfred W. Lam, Sten Myrehaug, Chia‐Lin Tseng, Zain Husain, Jay Detsky, Hany Soliman, Greg J. Stanisz
    Journal of Magnetic Resonance Imaging 2023 57 6
  • Radiomics-based convolutional neural network for brain tumor segmentation on multiparametric magnetic resonance imaging
    Prateek Prasanna, Ayush Karnawat, Marwa Ismail, Anant Madabhushi
    Journal of Medical Imaging 2019 6 02
  • Radiomics and Radiogenomics in Neuro-Oncology
    Teresa Perillo, Carmela Somma, Marco de Giorgi, Umberto Maria Papace, Sandra Perillo, Antonietta Serino, Andrea Manto, Renato Cuocolo
    2024
  • Current role of machine learning and radiogenomics in precision neuro-oncology
    Teresa Perillo, Marco de Giorgi, Umberto Maria Papace, Antonietta Serino, Renato Cuocolo, Andrea Manto
    Exploration of Targeted Anti-tumor Therapy 2023

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