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Research ArticleInterventional

Long-Term Results and Follow-Up Examinations after Endovascular Embolization for Unruptured Cerebral Aneurysms

T. Murakami, T. Nishida, K. Asai, Y. Kadono, H. Nakamura, T. Fujinaka and H. Kishima
American Journal of Neuroradiology July 2019, 40 (7) 1191-1196; DOI: https://doi.org/10.3174/ajnr.A6101
T. Murakami
aFrom the Department of Neurosurgery (T.M., T.N., K.A., Y.K., H.N., H.K.), Osaka University Graduate School of Medicine, Osaka, Japan
cDepartment of Neurosurgery (T.M.), Osaka Neurological Institute, Osaka, Japan.
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T. Nishida
aFrom the Department of Neurosurgery (T.M., T.N., K.A., Y.K., H.N., H.K.), Osaka University Graduate School of Medicine, Osaka, Japan
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K. Asai
aFrom the Department of Neurosurgery (T.M., T.N., K.A., Y.K., H.N., H.K.), Osaka University Graduate School of Medicine, Osaka, Japan
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Y. Kadono
aFrom the Department of Neurosurgery (T.M., T.N., K.A., Y.K., H.N., H.K.), Osaka University Graduate School of Medicine, Osaka, Japan
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H. Nakamura
aFrom the Department of Neurosurgery (T.M., T.N., K.A., Y.K., H.N., H.K.), Osaka University Graduate School of Medicine, Osaka, Japan
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T. Fujinaka
bDepartment of Neurosurgery (T.F.), Osaka National Hospital, Osaka, Japan
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H. Kishima
aFrom the Department of Neurosurgery (T.M., T.N., K.A., Y.K., H.N., H.K.), Osaka University Graduate School of Medicine, Osaka, Japan
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Abstract

BACKGROUND AND PURPOSE: The appropriate period of follow-up examinations after endovascular embolization for cerebral aneurysms using time-of-flight MR angiography is not well-known. We retrospectively investigated long-term results after endovascular embolization for unruptured cerebral aneurysms and evaluated the periods from embolization to recanalization and retreatment.

MATERIALS AND METHODS: Between April 2006 and March 2011, one hundred forty-eight unruptured aneurysms were treated with endovascular coil embolization. Among them, we investigated 116 unruptured aneurysms, which were followed up for >5 years. Time-of-flight MR angiography was performed at 1 day, 3–6 months, 1 year after the procedure, and every year thereafter.

RESULTS: The mean follow-up period was 7.0 ± 1.4 years. Recanalization was observed in 19 (16.3%) aneurysms within 2 years. Among them, retreatment for recanalization was performed in 8 (6.8%) aneurysms. No recanalization was detected in any aneurysms that had been stable in the first 2 years after embolization. A larger maximum aneurysm size was significantly correlated with recanalization (P = .019).

CONCLUSIONS: Aneurysms in which recanalization was not observed within 2 years after endovascular coil embolization were stable during a mean follow-up of 7 years. This result may be helpful in considering the appropriate span or frequency of follow-up imaging for embolized cerebral aneurysms.

ABBREVIATIONS:

BA
basilar artery
CO
complete obliteration
RA
residual aneurysm
RN
residual neck
  • © 2019 by American Journal of Neuroradiology
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American Journal of Neuroradiology: 40 (7)
American Journal of Neuroradiology
Vol. 40, Issue 7
1 Jul 2019
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Cite this article
T. Murakami, T. Nishida, K. Asai, Y. Kadono, H. Nakamura, T. Fujinaka, H. Kishima
Long-Term Results and Follow-Up Examinations after Endovascular Embolization for Unruptured Cerebral Aneurysms
American Journal of Neuroradiology Jul 2019, 40 (7) 1191-1196; DOI: 10.3174/ajnr.A6101

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Long-Term Results and Follow-Up Examinations after Endovascular Embolization for Unruptured Cerebral Aneurysms
T. Murakami, T. Nishida, K. Asai, Y. Kadono, H. Nakamura, T. Fujinaka, H. Kishima
American Journal of Neuroradiology Jul 2019, 40 (7) 1191-1196; DOI: 10.3174/ajnr.A6101
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