Widespread Increased Diffusivity Reveals Early Cortical Degeneration in Huntington Disease

F. Sampedro; S. Martínez-Horta; J. Perez-Perez; A. Horta-Barba; J. Martin-Lahoz; A. Alonso-Solís; I. Corripio; B. Gomez-Anson; J. Kulisevsky

doi:10.3174/ajnr.A6168

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Widespread Increased Diffusivity Reveals Early Cortical Degeneration in Huntington Disease

F. Sampedro, S. Martínez-Horta, J. Perez-Perez, A. Horta-Barba, J. Martin-Lahoz, A. Alonso-Solís, I. Corripio, B. Gomez-Anson and J. Kulisevsky

American Journal of Neuroradiology September 2019, 40 (9) 1464-1468; DOI: https://doi.org/10.3174/ajnr.A6168

F. Sampedro

aFrom the Movement Disorders Unit (F.S., S.M.-H., J.P.-P., A.H.-B., J.M.-L., J.K.), Neurology Department

dBiomedical Research Institute (F.S., S.M.-H., J.P.-P., A.H.-B., J.M.-L., A.A.-S., I.C., J.K.), Barcelona, Spain

eCentro de Investigación en Red-Enfermedades Neurodegenerativas (F.S., S.M.-H., J.P.-P., A.H.-B., J.M.-L., J.K.), Madrid, Spain

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S. Martínez-Horta

aFrom the Movement Disorders Unit (F.S., S.M.-H., J.P.-P., A.H.-B., J.M.-L., J.K.), Neurology Department

dBiomedical Research Institute (F.S., S.M.-H., J.P.-P., A.H.-B., J.M.-L., A.A.-S., I.C., J.K.), Barcelona, Spain

eCentro de Investigación en Red-Enfermedades Neurodegenerativas (F.S., S.M.-H., J.P.-P., A.H.-B., J.M.-L., J.K.), Madrid, Spain

fUniversitat Autónoma de Barcelona (S.M.-H., J.P.-P., J.M.-L., B.G.-A., J.K.), Barcelona, Spain

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J. Perez-Perez

aFrom the Movement Disorders Unit (F.S., S.M.-H., J.P.-P., A.H.-B., J.M.-L., J.K.), Neurology Department

dBiomedical Research Institute (F.S., S.M.-H., J.P.-P., A.H.-B., J.M.-L., A.A.-S., I.C., J.K.), Barcelona, Spain

eCentro de Investigación en Red-Enfermedades Neurodegenerativas (F.S., S.M.-H., J.P.-P., A.H.-B., J.M.-L., J.K.), Madrid, Spain

fUniversitat Autónoma de Barcelona (S.M.-H., J.P.-P., J.M.-L., B.G.-A., J.K.), Barcelona, Spain

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A. Horta-Barba

aFrom the Movement Disorders Unit (F.S., S.M.-H., J.P.-P., A.H.-B., J.M.-L., J.K.), Neurology Department

dBiomedical Research Institute (F.S., S.M.-H., J.P.-P., A.H.-B., J.M.-L., A.A.-S., I.C., J.K.), Barcelona, Spain

eCentro de Investigación en Red-Enfermedades Neurodegenerativas (F.S., S.M.-H., J.P.-P., A.H.-B., J.M.-L., J.K.), Madrid, Spain

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J. Martin-Lahoz

aFrom the Movement Disorders Unit (F.S., S.M.-H., J.P.-P., A.H.-B., J.M.-L., J.K.), Neurology Department

dBiomedical Research Institute (F.S., S.M.-H., J.P.-P., A.H.-B., J.M.-L., A.A.-S., I.C., J.K.), Barcelona, Spain

eCentro de Investigación en Red-Enfermedades Neurodegenerativas (F.S., S.M.-H., J.P.-P., A.H.-B., J.M.-L., J.K.), Madrid, Spain

fUniversitat Autónoma de Barcelona (S.M.-H., J.P.-P., J.M.-L., B.G.-A., J.K.), Barcelona, Spain

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A. Alonso-Solís

dBiomedical Research Institute (F.S., S.M.-H., J.P.-P., A.H.-B., J.M.-L., A.A.-S., I.C., J.K.), Barcelona, Spain

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I. Corripio

cPsychiatry Department (I.C.), Hospital de la Santa Creu i Sant Pau, Barcelona, Spain

dBiomedical Research Institute (F.S., S.M.-H., J.P.-P., A.H.-B., J.M.-L., A.A.-S., I.C., J.K.), Barcelona, Spain

hCentro de Investigación Biomédica en Red-Salud Mental (I.C.), Madrid, Spain.

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B. Gomez-Anson

bNeuroradiology, Radiology Department (B.G.-A.)

gEuropean Huntington's Disease Network (S.M.-H., J.P.-P., A.H.-B., J.K.), Ulm, Germany

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J. Kulisevsky

aFrom the Movement Disorders Unit (F.S., S.M.-H., J.P.-P., A.H.-B., J.M.-L., J.K.), Neurology Department

dBiomedical Research Institute (F.S., S.M.-H., J.P.-P., A.H.-B., J.M.-L., A.A.-S., I.C., J.K.), Barcelona, Spain

eCentro de Investigación en Red-Enfermedades Neurodegenerativas (F.S., S.M.-H., J.P.-P., A.H.-B., J.M.-L., J.K.), Madrid, Spain

gEuropean Huntington's Disease Network (S.M.-H., J.P.-P., A.H.-B., J.K.), Ulm, Germany

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F. Sampedro, S. Martínez-Horta, J. Perez-Perez, A. Horta-Barba, J. Martin-Lahoz, A. Alonso-Solís, I. Corripio, B. Gomez-Anson, J. Kulisevsky

Widespread Increased Diffusivity Reveals Early Cortical Degeneration in Huntington Disease

American Journal of Neuroradiology Sep 2019, 40 (9) 1464-1468; DOI: 10.3174/ajnr.A6168

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Widespread Increased Diffusivity Reveals Early Cortical Degeneration in Huntington Disease

F. Sampedro, S. Martínez-Horta, J. Perez-Perez, A. Horta-Barba, J. Martin-Lahoz, A. Alonso-Solís, I. Corripio, B. Gomez-Anson, J. Kulisevsky

American Journal of Neuroradiology Sep 2019, 40 (9) 1464-1468; DOI: 10.3174/ajnr.A6168

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