Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home

User menu

  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

ASHNR American Society of Functional Neuroradiology ASHNR American Society of Pediatric Neuroradiology ASSR
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds

AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Getting new auth cookie, if you see this message a lot, tell someone!
Research ArticleAdult Brain
Open Access

Distinguishing Extravascular from Intravascular Ferumoxytol Pools within the Brain: Proof of Concept in Patients with Treated Glioblastoma

R.F. Barajas, D. Schwartz, H.L. McConnell, C.N. Kersch, X. Li, B.E. Hamilton, J. Starkey, D.R. Pettersson, J.P. Nickerson, J.M. Pollock, R.F. Fu, A. Horvath, L. Szidonya, C.G. Varallyay, J.J. Jaboin, A.M. Raslan, A. Dogan, J.S. Cetas, J. Ciporen, S.J. Han, P. Ambady, L.L. Muldoon, R. Woltjer, W.D. Rooney and E.A. Neuwelt
American Journal of Neuroradiology July 2020, 41 (7) 1193-1200; DOI: https://doi.org/10.3174/ajnr.A6600
R.F. Barajas Jr
aFrom the Departments of Radiology (R.F.B. Jr, D.S., B.E.H., J.S., D.R.P., J.P.N., J.M.P., L.S., C.G.V.)
bAdvanced Imaging Research Center (R.F.B. Jr, D.S., X.L., A.H., W.D.R.)
cKnight Cancer Institute Translational Oncology Research Program (R.F.B. Jr)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for R.F. Barajas Jr
D. Schwartz
aFrom the Departments of Radiology (R.F.B. Jr, D.S., B.E.H., J.S., D.R.P., J.P.N., J.M.P., L.S., C.G.V.)
bAdvanced Imaging Research Center (R.F.B. Jr, D.S., X.L., A.H., W.D.R.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for D. Schwartz
H.L. McConnell
dDepartments of Neurology (H.L.M., C.N.K., L.S., C.G.V., P.A., L.L.M., E.A.N.)
iBlood-Brain Barrier Program (H.L.M., C.N.K., L.S., C.G.V., P.A., L.L.M., E.A.N.), Oregon Health & Science University, Portland, Oregon
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for H.L. McConnell
C.N. Kersch
dDepartments of Neurology (H.L.M., C.N.K., L.S., C.G.V., P.A., L.L.M., E.A.N.)
iBlood-Brain Barrier Program (H.L.M., C.N.K., L.S., C.G.V., P.A., L.L.M., E.A.N.), Oregon Health & Science University, Portland, Oregon
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for C.N. Kersch
X. Li
bAdvanced Imaging Research Center (R.F.B. Jr, D.S., X.L., A.H., W.D.R.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for X. Li
B.E. Hamilton
aFrom the Departments of Radiology (R.F.B. Jr, D.S., B.E.H., J.S., D.R.P., J.P.N., J.M.P., L.S., C.G.V.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for B.E. Hamilton
J. Starkey
aFrom the Departments of Radiology (R.F.B. Jr, D.S., B.E.H., J.S., D.R.P., J.P.N., J.M.P., L.S., C.G.V.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for J. Starkey
D.R. Pettersson
aFrom the Departments of Radiology (R.F.B. Jr, D.S., B.E.H., J.S., D.R.P., J.P.N., J.M.P., L.S., C.G.V.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for D.R. Pettersson
J.P. Nickerson
aFrom the Departments of Radiology (R.F.B. Jr, D.S., B.E.H., J.S., D.R.P., J.P.N., J.M.P., L.S., C.G.V.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for J.P. Nickerson
J.M. Pollock
aFrom the Departments of Radiology (R.F.B. Jr, D.S., B.E.H., J.S., D.R.P., J.P.N., J.M.P., L.S., C.G.V.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for J.M. Pollock
R.F. Fu
eMedical Informatics and Clinical Epidemiology (R.F.F.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for R.F. Fu
A. Horvath
bAdvanced Imaging Research Center (R.F.B. Jr, D.S., X.L., A.H., W.D.R.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for A. Horvath
L. Szidonya
aFrom the Departments of Radiology (R.F.B. Jr, D.S., B.E.H., J.S., D.R.P., J.P.N., J.M.P., L.S., C.G.V.)
dDepartments of Neurology (H.L.M., C.N.K., L.S., C.G.V., P.A., L.L.M., E.A.N.)
iBlood-Brain Barrier Program (H.L.M., C.N.K., L.S., C.G.V., P.A., L.L.M., E.A.N.), Oregon Health & Science University, Portland, Oregon
jDepartment of Diagnostic Radiology (L.S.), Heart and Vascular Center, Semmelweis University, Budapest, Hungary
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for L. Szidonya
C.G. Varallyay
aFrom the Departments of Radiology (R.F.B. Jr, D.S., B.E.H., J.S., D.R.P., J.P.N., J.M.P., L.S., C.G.V.)
dDepartments of Neurology (H.L.M., C.N.K., L.S., C.G.V., P.A., L.L.M., E.A.N.)
iBlood-Brain Barrier Program (H.L.M., C.N.K., L.S., C.G.V., P.A., L.L.M., E.A.N.), Oregon Health & Science University, Portland, Oregon
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for C.G. Varallyay
J.J. Jaboin
fRadiation Medicine (J.J.J.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for J.J. Jaboin
A.M. Raslan
gNeurological Surgery (A.M.R., A.D., J.S.C., J.C., S.J.H., E.A.N.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for A.M. Raslan
A. Dogan
gNeurological Surgery (A.M.R., A.D., J.S.C., J.C., S.J.H., E.A.N.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for A. Dogan
J.S. Cetas
gNeurological Surgery (A.M.R., A.D., J.S.C., J.C., S.J.H., E.A.N.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for J.S. Cetas
J. Ciporen
gNeurological Surgery (A.M.R., A.D., J.S.C., J.C., S.J.H., E.A.N.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for J. Ciporen
S.J. Han
gNeurological Surgery (A.M.R., A.D., J.S.C., J.C., S.J.H., E.A.N.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for S.J. Han
P. Ambady
dDepartments of Neurology (H.L.M., C.N.K., L.S., C.G.V., P.A., L.L.M., E.A.N.)
iBlood-Brain Barrier Program (H.L.M., C.N.K., L.S., C.G.V., P.A., L.L.M., E.A.N.), Oregon Health & Science University, Portland, Oregon
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for P. Ambady
L.L. Muldoon
dDepartments of Neurology (H.L.M., C.N.K., L.S., C.G.V., P.A., L.L.M., E.A.N.)
iBlood-Brain Barrier Program (H.L.M., C.N.K., L.S., C.G.V., P.A., L.L.M., E.A.N.), Oregon Health & Science University, Portland, Oregon
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for L.L. Muldoon
R. Woltjer
hPathology (R.W.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for R. Woltjer
W.D. Rooney
bAdvanced Imaging Research Center (R.F.B. Jr, D.S., X.L., A.H., W.D.R.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for W.D. Rooney
E.A. Neuwelt
dDepartments of Neurology (H.L.M., C.N.K., L.S., C.G.V., P.A., L.L.M., E.A.N.)
gNeurological Surgery (A.M.R., A.D., J.S.C., J.C., S.J.H., E.A.N.)
iBlood-Brain Barrier Program (H.L.M., C.N.K., L.S., C.G.V., P.A., L.L.M., E.A.N.), Oregon Health & Science University, Portland, Oregon
kPortland Veterans Affairs Medical Center (E.A.N.), Portland, Oregon.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for E.A. Neuwelt
  • Article
  • Figures & Data
  • Supplemental
  • Info & Metrics
  • Responses
  • References
  • PDF
Loading

References

  1. 1.↵
    1. Ostrom QT,
    2. Gittleman H,
    3. Xu J, et al
    . CBTRUS Statistical Report: Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2009–2013. Neuro Oncol 2016;18:v1–75 doi:10.1093/neuonc/now207 pmid:28475809
    CrossRefPubMed
  2. 2.↵
    1. Stupp R,
    2. Mason WP,
    3. van den Bent MJ, et al
    ; European Organisation for Research and Treatment of Cancer Brain Tumor and Radiotherapy Groups; National Cancer Institute of Canada Clinical Trials Group. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med 2005;352:987–96 doi:10.1056/NEJMoa043330 pmid:15758009
    CrossRefPubMedWeb of Science
  3. 3.↵
    1. Stupp R,
    2. Hegi ME,
    3. Mason WP, et al
    ; European Organisation for Research and Treatment of Cancer Brain Tumour and Radiation Oncology Groups; National Cancer Institute of Canada Clinical Trials Group. Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial. Lancet Oncol 2009;10:459–66 doi:10.1016/S1470-2045(09)70025-7 pmid:19269895
    CrossRefPubMedWeb of Science
  4. 4.↵
    1. Domingues P,
    2. Gonzalez-Tablas M,
    3. Otero A, et al
    . Tumor infiltrating immune cells in gliomas and meningiomas. Brain Behav Immun 2016;53:1–15 doi:10.1016/j.bbi.2015.07.019 pmid:26216710
    CrossRefPubMed
  5. 5.↵
    1. Macdonald DR,
    2. Cascino TL,
    3. Schold SC Jr., et al
    . Response criteria for phase II studies of supratentorial malignant glioma. J Clin Oncol 1990;8:1277–80 doi:10.1200/JCO.1990.8.7.1277 pmid:2358840
    Abstract
  6. 6.↵
    1. Wen PY,
    2. Macdonald DR,
    3. Reardon DA, et al
    . Updated response assessment criteria for high-grade gliomas: Response Assessment in Neuro-Oncology working group. J Clin Oncol 2010;28:1963–72 doi:10.1200/JCO.2009.26.3541 pmid:20231676
    Abstract/FREE Full Text
  7. 7.↵
    1. Okada H,
    2. Weller M,
    3. Huang R, et al
    . Immunotherapy response assessment in neuro-oncology: a report of the RANO working group. Lancet Oncol 2015;16:e534–42 doi:10.1016/S1470-2045(15)00088-1 pmid:26545842
    CrossRefPubMed
  8. 8.↵
    1. Li H,
    2. Li J,
    3. Cheng G, et al
    . IDH mutation and MGMT promoter methylation are associated with the pseudoprogression and improved prognosis of glioblastoma multiforme patients who have undergone concurrent and adjuvant temozolomide-based chemoradiotherapy. Clin Neurol Neurosurg 2016;151:31–36 doi:10.1016/j.clineuro.2016.10.004 pmid:27764705
    CrossRefPubMed
  9. 9.
    1. Gunjur A,
    2. Lau E,
    3. Taouk Y, et al
    . Early post-treatment pseudo-progression amongst glioblastoma multiforme patients treated with radiotherapy and temozolomide: a retrospective analysis. J Med Imaging Radiat Oncol 2011;55:603–10 doi:10.1111/j.1754-9485.2011.02319.x pmid:22141608
    CrossRefPubMed
  10. 10.↵
    1. Nasseri M,
    2. Gahramanov S,
    3. Netto JP, et al
    . Evaluation of pseudoprogression in patients with glioblastoma multiforme using dynamic magnetic resonance imaging with ferumoxytol calls RANO criteria into question. Neuro Oncol 2014;16:1146–54 doi:10.1093/neuonc/not328 pmid:24523362
    CrossRefPubMed
  11. 11.↵
    1. van Dijken BR,
    2. van Laar PJ,
    3. Holtman GA, et al
    . Diagnostic accuracy of magnetic resonance imaging techniques for treatment response evaluation in patients with high-grade glioma; a systematic review and meta-analysis. Eur Radiol 2017;27:4129–44 doi:10.1007/s00330-017-4789-9 pmid:28332014
    CrossRefPubMed
  12. 12.
    1. Grossman R,
    2. Shimony N,
    3. Hadelsberg U, et al
    . Impact of resecting radiation necrosis and pseudoprogression on survival of patients with glioblastoma. World Neurosurg 2016;89:37–41 doi:10.1016/j.wneu.2016.01.020 pmid:26805684
    CrossRefPubMed
  13. 13.↵
    1. Melguizo-Gavilanes I,
    2. Bruner JM,
    3. Guha-Thakurta N, et al
    . Characterization of pseudoprogression in patients with glioblastoma: is histology the gold standard? J Neurooncol 2015;123:141–50 doi:10.1007/s11060-015-1774-5 pmid:25894594
    CrossRefPubMed
  14. 14.↵
    1. Nairz M,
    2. Theurl I,
    3. Swirski FK, et al
    . “Pumping iron”—how macrophages handle iron at the systemic, microenvironmental, and cellular levels. Pflugers Arch 2017;469:397–418 doi:10.1007/s00424-017-1944-8 pmid:28251312
    CrossRefPubMed
  15. 15.↵
    1. McConnell HL,
    2. Schwartz DL,
    3. Richardson BE, et al
    . Ferumoxytol nanoparticle uptake in brain during acute neuroinflammation is cell-specific. Nanomedicine 2016;12:1535–42 doi:10.1016/j.nano.2016.03.009 pmid:27071335
    CrossRefPubMed
  16. 16.↵
    1. Toth GB,
    2. Varallyay CG,
    3. Horvath A, et al
    . Current and potential imaging applications of ferumoxytol for magnetic resonance imaging. Kidney Int 2017;92:47–66 doi:10.1016/j.kint.2016.12.037 pmid:28434822
    CrossRefPubMed
  17. 17.↵
    1. Varallyay CG,
    2. Nesbit E,
    3. Fu R, et al
    . High-resolution steady-state cerebral blood volume maps in patients with central nervous system neoplasms using ferumoxytol, a superparamagnetic iron oxide nanoparticle. J Cereb Blood Flow Metab 2013;33:780–86 doi:10.1038/jcbfm.2013.36 pmid:23486297
    CrossRefPubMed
  18. 18.↵
    1. Iv M,
    2. Samghabadi P,
    3. Holdsworth S, et al
    . Quantification of macrophages in high-grade gliomas by using ferumoxytol-enhanced MRI: a pilot study. Radiology 2019;290:198–206 doi:10.1148/radiol.2018181204 pmid:30398435
    CrossRefPubMed
  19. 19.↵
    1. Horvath A,
    2. Varallyay CG,
    3. Schwartz D, et al
    . Quantitative comparison of delayed ferumoxytol T1 enhancement with immediate gadoteridol enhancement in high grade gliomas. Magn Reson Med 2018;80:224–30 doi:10.1002/mrm.27028 pmid:29205477
    CrossRefPubMed
  20. 20.↵
    1. Bendszus M,
    2. Stoll G
    . Caught in the act: in vivo mapping of macrophage infiltration in nerve injury by magnetic resonance imaging. J Neurosci 2003;23:10892–96 pmid:14645484
    Abstract/FREE Full Text
  21. 21.↵
    1. Jackson C,
    2. Ruzevick J,
    3. Phallen J, et al
    . Challenges in immunotherapy presented by the glioblastoma multiforme microenvironment. Clin Dev Immunol 2011;2011:732413 doi:10.1155/2011/732413 pmid:22190972
    CrossRefPubMed
  22. 22.↵
    1. Wei B,
    2. Wang L,
    3. Zhao X, et al
    . The upregulation of programmed death 1 on peripheral blood T cells of glioma is correlated with disease progression. Tumor Biol 2014;35:2923–29 doi:10.1007/s13277-013-1376-9 pmid:24375192
    CrossRefPubMed
  23. 23.↵
    1. Heddleston JM,
    2. Li Z,
    3. McLendon RE, et al
    . The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype. Cell Cycle 2009;8:3274–84 doi:10.4161/cc.8.20.9701 pmid:19770585
    CrossRefPubMedWeb of Science
  24. 24.↵
    1. Barajas RF Jr.,
    2. Chang JS,
    3. Segal MR, et al
    . Differentiation of recurrent glioblastoma multiforme from radiation necrosis after external beam radiation therapy with dynamic susceptibility-weighted contrast-enhanced perfusion MRI. Radiology 2009;253:486–96 doi:10.1148/radiol.2532090007 pmid:9789240
    CrossRefPubMedWeb of Science
  25. 25.↵
    1. Barajas RF Jr.,
    2. Hamilton BE,
    3. Schwartz D, et al
    . Combined iron oxide nanoparticle ferumoxytol and gadolinium contrast enhanced MRI defines glioblastoma pseudo-progression. Neuro Oncol 2019;21:517–26 doi:10.1093/neuonc/noy160 pmid:30277536
    CrossRefPubMed
  26. 26.↵
    1. Barajas RF Jr.,
    2. Hodgson JG,
    3. Chang JS, et al
    . Glioblastoma multiforme regional genetic and cellular expression patterns: influence on anatomic and physiologic MR imaging. Radiology 2010;254:564–76 doi:10.1148/radiol.09090663 pmid:20093527
    CrossRefPubMedWeb of Science
  27. 27.↵
    1. Ranjan S,
    2. Quezado M,
    3. Garren N, et al
    . Clinical decision making in the era of immunotherapy for high grade-glioma: report of four cases. BMC Cancer 2018;18:239 doi:10.1186/s12885-018-4131-1 pmid:29490632
    CrossRefPubMed
  28. 28.↵
    1. Gordon SR,
    2. Maute RL,
    3. Dulken BW, et al
    . PD-1 expression by tumour-associated macrophages inhibits phagocytosis and tumour immunity. Nature 2017;545:495–99 doi:10.1038/nature22396 pmid:28514441
    CrossRefPubMed
  29. 29.↵
    1. Nguyen KL,
    2. Yoshida T,
    3. Kathuria-Prakash N, et al
    . Multicenter safety and practice for off-label diagnostic use of ferumoxytol in MRI. Radiology 2019;293:554–64 doi:10.1148/radiol.2019190477 pmid:31638489
    CrossRefPubMed
PreviousNext
Back to top

In this issue

American Journal of Neuroradiology: 41 (7)
American Journal of Neuroradiology
Vol. 41, Issue 7
1 Jul 2020
  • Table of Contents
  • Index by author
  • Complete Issue (PDF)
Advertisement
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Distinguishing Extravascular from Intravascular Ferumoxytol Pools within the Brain: Proof of Concept in Patients with Treated Glioblastoma
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Cite this article
R.F. Barajas, D. Schwartz, H.L. McConnell, C.N. Kersch, X. Li, B.E. Hamilton, J. Starkey, D.R. Pettersson, J.P. Nickerson, J.M. Pollock, R.F. Fu, A. Horvath, L. Szidonya, C.G. Varallyay, J.J. Jaboin, A.M. Raslan, A. Dogan, J.S. Cetas, J. Ciporen, S.J. Han, P. Ambady, L.L. Muldoon, R. Woltjer, W.D. Rooney, E.A. Neuwelt
Distinguishing Extravascular from Intravascular Ferumoxytol Pools within the Brain: Proof of Concept in Patients with Treated Glioblastoma
American Journal of Neuroradiology Jul 2020, 41 (7) 1193-1200; DOI: 10.3174/ajnr.A6600

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
0 Responses
Respond to this article
Share
Bookmark this article
Distinguishing Extravascular from Intravascular Ferumoxytol Pools within the Brain: Proof of Concept in Patients with Treated Glioblastoma
R.F. Barajas, D. Schwartz, H.L. McConnell, C.N. Kersch, X. Li, B.E. Hamilton, J. Starkey, D.R. Pettersson, J.P. Nickerson, J.M. Pollock, R.F. Fu, A. Horvath, L. Szidonya, C.G. Varallyay, J.J. Jaboin, A.M. Raslan, A. Dogan, J.S. Cetas, J. Ciporen, S.J. Han, P. Ambady, L.L. Muldoon, R. Woltjer, W.D. Rooney, E.A. Neuwelt
American Journal of Neuroradiology Jul 2020, 41 (7) 1193-1200; DOI: 10.3174/ajnr.A6600
del.icio.us logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Purchase

Jump to section

  • Article
    • Abstract
    • ABBREVIATIONS:
    • MATERIALS AND METHODS
    • RESULTS
    • DISCUSSION
    • CONCLUSIONS
    • ACKNOWLEDGMENTS
    • Footnotes
    • References
  • Figures & Data
  • Supplemental
  • Info & Metrics
  • Responses
  • References
  • PDF

Related Articles

  • PubMed
  • Google Scholar

Cited By...

  • Enhanced Detection of Glioblastoma Vasculature with Superparamagnetic Iron Oxide Nanoparticles and MRI
  • Crossref
  • Google Scholar

This article has not yet been cited by articles in journals that are participating in Crossref Cited-by Linking.

More in this TOC Section

  • Diagnostic Neuroradiology of Monoclonal Antibodies
  • Segmentation of Brain Metastases with BLAST
  • Cerebral ADC Changes in Fabry Disease
Show more Adult Brain

Similar Articles

Advertisement

Indexed Content

  • Current Issue
  • Accepted Manuscripts
  • Article Preview
  • Past Issues
  • Editorials
  • Editor's Choice
  • Fellows' Journal Club
  • Letters to the Editor
  • Video Articles

Cases

  • Case Collection
  • Archive - Case of the Week
  • Archive - Case of the Month
  • Archive - Classic Case

More from AJNR

  • Trainee Corner
  • Imaging Protocols
  • MRI Safety Corner
  • Book Reviews

Multimedia

  • AJNR Podcasts
  • AJNR Scantastics

Resources

  • Turnaround Time
  • Submit a Manuscript
  • Submit a Video Article
  • Submit an eLetter to the Editor/Response
  • Manuscript Submission Guidelines
  • Statistical Tips
  • Fast Publishing of Accepted Manuscripts
  • Graphical Abstract Preparation
  • Imaging Protocol Submission
  • Evidence-Based Medicine Level Guide
  • Publishing Checklists
  • Author Policies
  • Become a Reviewer/Academy of Reviewers
  • News and Updates

About Us

  • About AJNR
  • Editorial Board
  • Editorial Board Alumni
  • Alerts
  • Permissions
  • Not an AJNR Subscriber? Join Now
  • Advertise with Us
  • Librarian Resources
  • Feedback
  • Terms and Conditions
  • AJNR Editorial Board Alumni

American Society of Neuroradiology

  • Not an ASNR Member? Join Now

© 2025 by the American Society of Neuroradiology All rights, including for text and data mining, AI training, and similar technologies, are reserved.
Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire