Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home

User menu

  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

ASHNR American Society of Functional Neuroradiology ASHNR American Society of Pediatric Neuroradiology ASSR
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds

AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Research ArticleAdult Brain

Dedicated 3D-T2-STIR-ZOOMit Imaging Improves Demyelinating Lesion Detection in the Anterior Visual Pathways of Patients with Multiple Sclerosis

E. Pravatà, L. Roccatagliata, M.P. Sormani, L. Carmisciano, C. Lienerth, R. Sacco, A. Kaelin-Lang, A. Cianfoni, C. Zecca and C. Gobbi
American Journal of Neuroradiology June 2021, 42 (6) 1061-1068; DOI: https://doi.org/10.3174/ajnr.A7082
E. Pravatà
aFrom the Department of Neuroradiology (E.P., A.C.), Neurocenter of Southern Switzerland, Lugano, Switzerland
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for E. Pravatà
L. Roccatagliata
bDepartment of Health Sciences (L.R., M.P.S., L.C.), University of Genova, Genova, Italy
cDipartimento di Scienze della Salute – DISSAL (L.R., M.P.S.), Istituto di Ricovero e Cura a Carattere Scientifico Ospedale Policlinico San Martino, Genoa, Italy
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for L. Roccatagliata
M.P. Sormani
bDepartment of Health Sciences (L.R., M.P.S., L.C.), University of Genova, Genova, Italy
cDipartimento di Scienze della Salute – DISSAL (L.R., M.P.S.), Istituto di Ricovero e Cura a Carattere Scientifico Ospedale Policlinico San Martino, Genoa, Italy
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for M.P. Sormani
L. Carmisciano
bDepartment of Health Sciences (L.R., M.P.S., L.C.), University of Genova, Genova, Italy
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for L. Carmisciano
C. Lienerth
dBayer Vital GmbH (C.L.), Leverkusen, Germany
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for C. Lienerth
R. Sacco
eDepartment of Neurology (R.S., A.K.-L., C.Z., C.G.), Neurocenter of Southern Switzerland, Lugano, Switzerland
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for R. Sacco
A. Kaelin-Lang
eDepartment of Neurology (R.S., A.K.-L., C.Z., C.G.), Neurocenter of Southern Switzerland, Lugano, Switzerland
fFaculty of Biomedical Sciences (A.K.-L., A.C., C.Z., C.G.), Università della Svizzera Italiana, Lugano, Switzerland
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for A. Kaelin-Lang
A. Cianfoni
aFrom the Department of Neuroradiology (E.P., A.C.), Neurocenter of Southern Switzerland, Lugano, Switzerland
fFaculty of Biomedical Sciences (A.K.-L., A.C., C.Z., C.G.), Università della Svizzera Italiana, Lugano, Switzerland
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for A. Cianfoni
C. Zecca
eDepartment of Neurology (R.S., A.K.-L., C.Z., C.G.), Neurocenter of Southern Switzerland, Lugano, Switzerland
fFaculty of Biomedical Sciences (A.K.-L., A.C., C.Z., C.G.), Università della Svizzera Italiana, Lugano, Switzerland
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for C. Zecca
C. Gobbi
eDepartment of Neurology (R.S., A.K.-L., C.Z., C.G.), Neurocenter of Southern Switzerland, Lugano, Switzerland
fFaculty of Biomedical Sciences (A.K.-L., A.C., C.Z., C.G.), Università della Svizzera Italiana, Lugano, Switzerland
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for C. Gobbi
  • Article
  • Figures & Data
  • Supplemental
  • Info & Metrics
  • Responses
  • References
  • PDF
Loading

References

  1. 1.↵
    1. Reich DS,
    2. Lucchinetti CF,
    3. Calabresi PA
    . Multiple sclerosis. N Engl J Med 2018;378:169–80 doi:10.1056/NEJMra1401483 pmid:29320652
    CrossRefPubMed
  2. 2.↵
    1. Dutra BG,
    2. Da Rocha AJ,
    3. Nunes RH, et al
    . Neuromyelitis optica spectrum disorders: spectrum of MR imaging findings and their differential diagnosis. Radiographics 2018;38:169–93 doi:10.1148/rg.2018170141 pmid:29320331
    CrossRefPubMed
  3. 3.↵
    1. Ulrich J,
    2. Groebke-Lorenz W
    . The optic nerve in multiple sclerosis: a morphological study with retrospective clinico-pathological correlations. Neuro-Ophthalmology 1983;3:149–59 doi:10.3109/01658108309009732
    CrossRef
  4. 4.↵
    1. Balcer LJ,
    2. Frohman EM
    . Evaluating loss of visual function in multiple sclerosis as measured by low-contrast letter acuity. Neurology 2010;74:S16–23 doi:10.1212/WNL.0b013e3181dbb664 pmid:20421569
    Abstract/FREE Full Text
  5. 5.↵
    1. Filippi M,
    2. Rocca MA,
    3. Ciccarelli O, et al
    . MRI criteria for the diagnosis of multiple sclerosis: MAGNIMS consensus guidelines. Lancet Neurol 2016;15:292–303 doi:10.1016/S1474-4422(15)00393-2 pmid:26822746
    CrossRefPubMed
  6. 6.↵
    1. Thompson AJ,
    2. Banwell BL,
    3. Barkhof F, et al
    . Diagnosis of multiple sclerosis: 2017 revisions of the McDonald criteria. Lancet Neurol 2018;17:162–73 doi:10.1016/S1474-4422(17)30470-2 pmid:29275977
    CrossRefPubMed
  7. 7.↵
    1. Sormani MP,
    2. De Stefano N
    . Defining and scoring response to IFN-β in multiple sclerosis. Nat Rev Neurol 2013;9:504–12 doi:10.1038/nrneurol.2013.146 pmid:23897407
    CrossRefPubMed
  8. 8.↵
    1. Petzold A,
    2. Wattjes MP,
    3. Costello F, et al
    . The investigation of acute optic neuritis: a review and proposed protocol. Nat Rev Neurol 2014;10:447–58 doi:10.1038/nrneurol.2014.108 pmid:25002105
    CrossRefPubMed
  9. 9.↵
    1. Polman CH,
    2. Reingold SC,
    3. Banwell B, et al
    . Diagnostic criteria for multiple sclerosis: 2010 Revisions to the McDonald Criteria. Ann Neurol 2011;69:292–302 doi:10.1002/ana.22366 pmid:21387374
    CrossRefPubMedWeb of Science
  10. 10.↵
    1. Blasche M,
    2. Riffel P,
    3. Lichy M
    . TimTX TrueShape and syngo ZOOMit: technical and practical aspects. MAGNETOM Flash 2012 https://cdn0.scrvt.com/39b415fb07de4d9656c7b516d8e2d907/1800000000118051/a06d5db36c83/TimTX_TrueShape_and_syngo_Zoomit_Aspects_1800000000118051.pdf. Accessed January 01, 2020
  11. 11.↵
    1. Fang S,
    2. Bai HX,
    3. Fan X, et al
    . A novel sequence: ZOOMit-blood oxygen level-dependent for motor-cortex localization. Clin Neurosurg 2020;86:E124–32 doi:10.1093/neuros/nyz441 pmid:31642505
    CrossRefPubMed
  12. 12.↵
    1. Bot JC,
    2. Barkhof F,
    3. Lycklama À, et al
    . Comparison of a conventional cardiac-triggered dual spin-echo and a fast STIR sequence in detection of spinal cord lesion in multiples sclerosis. Eur Radiol 2000;10:753–58 doi:10.1007/s003300050998 pmid:10823627
    CrossRefPubMed
  13. 13.↵
    1. Thorpe JW,
    2. MacManus DG,
    3. Kendall BE, et al
    . Short tau inversion recovery fast spin-echo (fast STIR) imaging of the spinal cord in multiple sclerosis. Magn Reson Imaging 1994;12:983–89 doi:10.1016/0730-725X(94)91228-O pmid:7997103
    CrossRefPubMed
  14. 14.↵
    1. Hodel J,
    2. Outteryck O,
    3. Bocher AL, et al
    . Comparison of 3D double inversion recovery and 2D STIR FLAIR MR sequences for the imaging of optic neuritis: pilot study. Eur Radiol 2014;24:3069–75 doi:10.1007/s00330-014-3342-3
    CrossRefPubMed
  15. 15.↵
    1. Kurtzke JF
    . Rating neurologic impairment in multiple sclerosis: An Expanded Disability Status Scale (EDSS). Neurology 1983;33:1444–52 doi:10.1212/wnl.33.11.1444 pmid:6685237
    Abstract/FREE Full Text
  16. 16.↵
    1. Geraldes R,
    2. Ciccarelli O,
    3. Barkhof F, et al
    . MAGNIMS study group. The current role of MRI in differentiating multiple sclerosis from its imaging mimics. Nat Rev Neurol 2018;14:199–213 doi:10.1038/nrneurol.2018.14 pmid:29582852
    CrossRefPubMed
  17. 17.↵
    1. Bink A,
    2. Schmitt M,
    3. Gaa J, et al
    . Detection of lesions in multiple sclerosis by 2D FLAIR and single-slab 3D FLAIR sequences at 3.0 T: initial results. Eur Radiol 2006;16:1104–10 doi:10.1007/s00330-005-0107-z pmid:16425026
    CrossRefPubMedWeb of Science
  18. 18.↵
    1. Molyneux PD,
    2. Tubridy N,
    3. Parker GJ, et al
    . The effect of section thickness on MR lesion detection and quantification in multiple sclerosis. AJNR Am J Neuroradiol 1998;19:1715–20 pmid:30446963
    Abstract
  19. 19.↵
    1. Moraal B,
    2. Roosendaal SD,
    3. Pouwels PJ, et al
    . Multi-contrast, isotropic, single-slab 3D MR imaging in multiple sclerosis. Eur Radiol 2008;18:2311–20 doi:10.1007/s00330-008-1009-7 pmid:18509658
    CrossRefPubMedWeb of Science
  20. 20.↵
    1. Kallmes DF,
    2. Hui FK,
    3. Mugler JP
    . Suppression of cerebrospinal fluid and blood flow artifacts in FLAIR MR imaging with a single-slab three-dimensional pulse sequence: Initial experience. Radiology 2001;221:251–55 doi:10.1148/radiol.2211001712 pmid:11568348
    CrossRefPubMed
  21. 21.↵
    1. Kneeland JB,
    2. Shimakawa A,
    3. Wehrli FW
    . Effect of intersection spacing on MR image contrast and study time. Radiology 1986;158:819–22 doi:10.1148/radiology.158.3.3945757 pmid:3945757
    CrossRefPubMed
  22. 22.↵
    1. Sartoretti T,
    2. Sartoretti E,
    3. Rauch S, et al
    . How common is signal-intensity increase in optic nerve segments on 3D double inversion recovery sequences in visually asymptomatic patients with multiple sclerosis? AJNR Am J Neuroradiol 2017;38:1748–53 doi:10.3174/ajnr.A5262 pmid:28663263
    Abstract/FREE Full Text
  23. 23.↵
    1. Hadhoum N,
    2. Hodel J,
    3. Defoort-Dhellemmes S, et al
    . Length of optic nerve double inversion recovery hypersignal is associated with retinal axonal loss. Mult Scler 2016;22:649–58 doi:10.1177/1352458515598021 pmid:26227005
    CrossRefPubMed
  24. 24.↵
    1. Riederer I,
    2. Mühlau M,
    3. Hoshi MM, et al
    . Detecting optic nerve lesions in clinically isolated syndrome and multiple sclerosis: double-inversion recovery magnetic resonance imaging in comparison with visually evoked potentials. J Neurol 2019;266:148–56 doi:10.1007/s00415-018-9114-2 pmid:30446963
    CrossRefPubMed
  25. 25.↵
    1. Traboulsee A,
    2. Simon JH,
    3. Stone L, et al
    . Revised recommendations of the consortium of MS centers task force for a standardized MRI protocol and clinical guidelines for the diagnosis and follow-up of multiple sclerosis. AJNR Am J Neuroradiol 2016;37:394–401 doi:10.3174/ajnr.A4539 pmid:26564433
    Abstract/FREE Full Text
  26. 26.↵
    1. Yuhasz M,
    2. Hoch MJ,
    3. Hagiwara M, et al
    . Accelerated internal auditory canal screening magnetic resonance imaging protocol with compressed sensing 3-dimensional T2-weighted sequence. Invest Radiol 2018;53:742–47 doi:10.1097/RLI.0000000000000499 pmid:30020139
    CrossRefPubMed
  27. 27.↵
    1. Fritz J,
    2. Fritz B,
    3. Thawait GG, et al
    . Three-dimensional CAIPIRINHA SPACE TSE for 5-minute high-resolution MRI of the knee. Invest Radiol 2016;51:609–17 doi:10.1097/RLI.0000000000000287 pmid:27187045
    CrossRefPubMed
  28. 28.↵
    1. White N,
    2. Roddey C,
    3. Shankaranarayanan A, et al
    . PROMO: real-time prospective motion correction in MRI using image-based tracking. Magn Reson Med 2010;63:91–105 doi:10.1002/mrm.22176 pmid:20027635
    CrossRefPubMed
PreviousNext
Back to top

In this issue

American Journal of Neuroradiology: 42 (6)
American Journal of Neuroradiology
Vol. 42, Issue 6
1 Jun 2021
  • Table of Contents
  • Index by author
  • Complete Issue (PDF)
Advertisement
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Dedicated 3D-T2-STIR-ZOOMit Imaging Improves Demyelinating Lesion Detection in the Anterior Visual Pathways of Patients with Multiple Sclerosis
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Cite this article
E. Pravatà, L. Roccatagliata, M.P. Sormani, L. Carmisciano, C. Lienerth, R. Sacco, A. Kaelin-Lang, A. Cianfoni, C. Zecca, C. Gobbi
Dedicated 3D-T2-STIR-ZOOMit Imaging Improves Demyelinating Lesion Detection in the Anterior Visual Pathways of Patients with Multiple Sclerosis
American Journal of Neuroradiology Jun 2021, 42 (6) 1061-1068; DOI: 10.3174/ajnr.A7082

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
0 Responses
Respond to this article
Share
Bookmark this article
Dedicated 3D-T2-STIR-ZOOMit Imaging Improves Demyelinating Lesion Detection in the Anterior Visual Pathways of Patients with Multiple Sclerosis
E. Pravatà, L. Roccatagliata, M.P. Sormani, L. Carmisciano, C. Lienerth, R. Sacco, A. Kaelin-Lang, A. Cianfoni, C. Zecca, C. Gobbi
American Journal of Neuroradiology Jun 2021, 42 (6) 1061-1068; DOI: 10.3174/ajnr.A7082
del.icio.us logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Purchase

Jump to section

  • Article
    • Abstract
    • ABBREVIATIONS:
    • MATERIALS AND METHODS
    • RESULTS
    • DISCUSSION
    • CONCLUSIONS
    • ACKNOWLEDGMENTS
    • Footnotes
    • References
  • Figures & Data
  • Supplemental
  • Info & Metrics
  • Responses
  • References
  • PDF

Related Articles

  • PubMed
  • Google Scholar

Cited By...

  • Nonlesional Sources of Contrast Enhancement on Postgadolinium "Black-Blood" 3D T1-SPACE Images in Patients with Multiple Sclerosis
  • Crossref
  • Google Scholar

This article has not yet been cited by articles in journals that are participating in Crossref Cited-by Linking.

More in this TOC Section

  • Diagnostic Neuroradiology of Monoclonal Antibodies
  • Clinical Outcomes After Chiari I Decompression
  • Segmentation of Brain Metastases with BLAST
Show more Adult Brain

Similar Articles

Advertisement

Indexed Content

  • Current Issue
  • Accepted Manuscripts
  • Article Preview
  • Past Issues
  • Editorials
  • Editor's Choice
  • Fellows' Journal Club
  • Letters to the Editor
  • Video Articles

Cases

  • Case Collection
  • Archive - Case of the Week
  • Archive - Case of the Month
  • Archive - Classic Case

More from AJNR

  • Trainee Corner
  • Imaging Protocols
  • MRI Safety Corner
  • Book Reviews

Multimedia

  • AJNR Podcasts
  • AJNR Scantastics

Resources

  • Turnaround Time
  • Submit a Manuscript
  • Submit a Video Article
  • Submit an eLetter to the Editor/Response
  • Manuscript Submission Guidelines
  • Statistical Tips
  • Fast Publishing of Accepted Manuscripts
  • Graphical Abstract Preparation
  • Imaging Protocol Submission
  • Evidence-Based Medicine Level Guide
  • Publishing Checklists
  • Author Policies
  • Become a Reviewer/Academy of Reviewers
  • News and Updates

About Us

  • About AJNR
  • Editorial Board
  • Editorial Board Alumni
  • Alerts
  • Permissions
  • Not an AJNR Subscriber? Join Now
  • Advertise with Us
  • Librarian Resources
  • Feedback
  • Terms and Conditions
  • AJNR Editorial Board Alumni

American Society of Neuroradiology

  • Not an ASNR Member? Join Now

© 2025 by the American Society of Neuroradiology All rights, including for text and data mining, AI training, and similar technologies, are reserved.
Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire