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Research ArticleAdult Brain
Open Access

Cerebral Venous Thrombosis in COVID-19: A New York Metropolitan Cohort Study

F. Al-Mufti, K. Amuluru, R. Sahni, K. Bekelis, R. Karimi, J. Ogulnick, J. Cooper, P. Overby, R. Nuoman, A. Tiwari, K. Berekashvili, N. Dangayach, J. Liang, G. Gupta, P. Khandelwal, J.F. Dominguez, T. Sursal, H. Kamal, K. Dakay, B. Taylor, E. Gulko, M. El-Ghanem, S.A. Mayer and C. Gandhi
American Journal of Neuroradiology July 2021, 42 (7) 1196-1200; DOI: https://doi.org/10.3174/ajnr.A7134
F. Al-Mufti
aFrom the Departments of Neurosurgery (F.A.-M., R.S., J.C., P.O., R.N., J.F.D., T.S., E.G., S.A.M., C.G.)
bNeurology (F.A.-M., R.S., J.O., H.K., K.D., E.G., S.A.M., C.G.), Westchester Medical Center at New York Medical College, Valhalla, New York
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  • ORCID record for F. Al-Mufti
K. Amuluru
iDepartment of Radiology (K.A.), Goodman Campbell Brain and Spine, Indianapolis, Indiana.
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R. Sahni
aFrom the Departments of Neurosurgery (F.A.-M., R.S., J.C., P.O., R.N., J.F.D., T.S., E.G., S.A.M., C.G.)
bNeurology (F.A.-M., R.S., J.O., H.K., K.D., E.G., S.A.M., C.G.), Westchester Medical Center at New York Medical College, Valhalla, New York
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K. Bekelis
cDepartment of Neurosurgery (K. Bekelis), Catholic Health Services and Good Samaritan Hospital, West Islip, New York
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R. Karimi
dDepartment of Neurosurgery (R.K.), Hackensack University Medical Center, Hackensack, New Jersey
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J. Ogulnick
bNeurology (F.A.-M., R.S., J.O., H.K., K.D., E.G., S.A.M., C.G.), Westchester Medical Center at New York Medical College, Valhalla, New York
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J. Cooper
aFrom the Departments of Neurosurgery (F.A.-M., R.S., J.C., P.O., R.N., J.F.D., T.S., E.G., S.A.M., C.G.)
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P. Overby
aFrom the Departments of Neurosurgery (F.A.-M., R.S., J.C., P.O., R.N., J.F.D., T.S., E.G., S.A.M., C.G.)
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R. Nuoman
aFrom the Departments of Neurosurgery (F.A.-M., R.S., J.C., P.O., R.N., J.F.D., T.S., E.G., S.A.M., C.G.)
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A. Tiwari
eDepartment of Neurosurgery (A.T., K. Berekashvili), New York University, New York, New York
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K. Berekashvili
eDepartment of Neurosurgery (A.T., K. Berekashvili), New York University, New York, New York
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  • ORCID record for K. Berekashvili
N. Dangayach
fDepartment of Neurosurgery (N.D., J.L.), Icahn School of Medicine at Mount Sinai, New York, New York
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J. Liang
fDepartment of Neurosurgery (N.D., J.L.), Icahn School of Medicine at Mount Sinai, New York, New York
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G. Gupta
gDepartment of Neurological Surgery (G.G., P.K., B.T.), Rutgers University, New Brunswick, New Jersey
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P. Khandelwal
gDepartment of Neurological Surgery (G.G., P.K., B.T.), Rutgers University, New Brunswick, New Jersey
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J.F. Dominguez
aFrom the Departments of Neurosurgery (F.A.-M., R.S., J.C., P.O., R.N., J.F.D., T.S., E.G., S.A.M., C.G.)
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T. Sursal
aFrom the Departments of Neurosurgery (F.A.-M., R.S., J.C., P.O., R.N., J.F.D., T.S., E.G., S.A.M., C.G.)
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H. Kamal
bNeurology (F.A.-M., R.S., J.O., H.K., K.D., E.G., S.A.M., C.G.), Westchester Medical Center at New York Medical College, Valhalla, New York
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K. Dakay
bNeurology (F.A.-M., R.S., J.O., H.K., K.D., E.G., S.A.M., C.G.), Westchester Medical Center at New York Medical College, Valhalla, New York
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B. Taylor
gDepartment of Neurological Surgery (G.G., P.K., B.T.), Rutgers University, New Brunswick, New Jersey
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E. Gulko
aFrom the Departments of Neurosurgery (F.A.-M., R.S., J.C., P.O., R.N., J.F.D., T.S., E.G., S.A.M., C.G.)
bNeurology (F.A.-M., R.S., J.O., H.K., K.D., E.G., S.A.M., C.G.), Westchester Medical Center at New York Medical College, Valhalla, New York
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M. El-Ghanem
hDepartment of Neurology (M.E.-G.), University of Arizona-Tuscon, Tuscon, Arizona
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S.A. Mayer
aFrom the Departments of Neurosurgery (F.A.-M., R.S., J.C., P.O., R.N., J.F.D., T.S., E.G., S.A.M., C.G.)
bNeurology (F.A.-M., R.S., J.O., H.K., K.D., E.G., S.A.M., C.G.), Westchester Medical Center at New York Medical College, Valhalla, New York
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C. Gandhi
aFrom the Departments of Neurosurgery (F.A.-M., R.S., J.C., P.O., R.N., J.F.D., T.S., E.G., S.A.M., C.G.)
bNeurology (F.A.-M., R.S., J.O., H.K., K.D., E.G., S.A.M., C.G.), Westchester Medical Center at New York Medical College, Valhalla, New York
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Figures

  • FIG 1.
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    FIG 1.

    A, NCCT shows hyperdense thrombus in the region of the torcula and subtle cortical hyperdensity along the right temporo-occipital region (arrows). Sagittal (B) and coronal MIP (C) reformatted images of CTA show multiple filling defects along the posterior superior sagittal sinus (double arrows), torcula, and right transverse sinus. Note a parenchymal hematoma in the right occipital lobe. D, MR imaging of the brain; gradient recalled-echo sequence shows thrombus in the sagittal sinus and associated parenchymal hematoma.

  • FIG 2.
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    FIG 2.

    A, NCCT shows a subtle hyperdense thrombus in left transverse sinus. MR imaging of the brain: T1 postgadolinium images in axial (B) and sagittal (C) projections and MRV (D) with gadolinium showing sinus thrombosis of the torcula with extension to the bilateral, left-greater-than-right, transverse sinuses. E, Endovascular microcatheter venogram shows progression of thrombus throughout superior sagittal sinus. F, A postinterventional venogram shows improved patency after mechanical thrombectomy.

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American Journal of Neuroradiology: 42 (7)
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F. Al-Mufti, K. Amuluru, R. Sahni, K. Bekelis, R. Karimi, J. Ogulnick, J. Cooper, P. Overby, R. Nuoman, A. Tiwari, K. Berekashvili, N. Dangayach, J. Liang, G. Gupta, P. Khandelwal, J.F. Dominguez, T. Sursal, H. Kamal, K. Dakay, B. Taylor, E. Gulko, M. El-Ghanem, S.A. Mayer, C. Gandhi
Cerebral Venous Thrombosis in COVID-19: A New York Metropolitan Cohort Study
American Journal of Neuroradiology Jul 2021, 42 (7) 1196-1200; DOI: 10.3174/ajnr.A7134

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Cerebral Venous Thrombosis in COVID-19: A New York Metropolitan Cohort Study
F. Al-Mufti, K. Amuluru, R. Sahni, K. Bekelis, R. Karimi, J. Ogulnick, J. Cooper, P. Overby, R. Nuoman, A. Tiwari, K. Berekashvili, N. Dangayach, J. Liang, G. Gupta, P. Khandelwal, J.F. Dominguez, T. Sursal, H. Kamal, K. Dakay, B. Taylor, E. Gulko, M. El-Ghanem, S.A. Mayer, C. Gandhi
American Journal of Neuroradiology Jul 2021, 42 (7) 1196-1200; DOI: 10.3174/ajnr.A7134
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