Can Shunt Response in Patients with Idiopathic Normal Pressure Hydrocephalus Be Predicted from Preoperative Brain Imaging? A Retrospective Study of the Diagnostic Use of the Normal Pressure Hydrocephalus Radscale in 119 Patients

References

1. 1.↵
   1. Fasano A,
   2. Espay AJ,
   3. Tang-Wai DF, et al

   . Gaps, controversies, and proposed roadmap for research in normal pressure hydrocephalus. Mov Disord 2020;35:1945–54 doi:10.1002/mds.28251 pmid:32959936

   CrossRefPubMed
2. 2.↵
   1. Wang Z,
   2. Zhang Y,
   3. Hu F, et al

   . Pathogenesis and pathophysiology of idiopathic normal pressure hydrocephalus. CNS Neurosci Ther 2020;26:1230–40 doi:10.1111/cns.13526 pmid:33242372

   CrossRefPubMed
3. 3.↵
   1. Bassi MA,
   2. Lopez MA,
   3. Confalone L, et al

   . Normal pressure hydrocephalus: diagnosis and treatment. Nature 2020;388:539–47 doi:10.1007/s11910-008-0058-2 pmid:9252185

   CrossRefPubMed
4. 4.↵
   1. Andersson J,
   2. Rosell M,
   3. Kockum K, et al

   . Challenges in diagnosing normal pressure hydrocephalus: evaluation of the diagnostic guidelines. eNeurologicalSci 2017;7:27–31 doi:10.1016/j.ensci.2017.04.002 pmid:29302622

   CrossRefPubMed
5. 5.↵
   1. Halperin JJ,
   2. Kurlan R,
   3. Schwalb JM, et al

   . Practice guideline: idiopathic normal pressure hydrocephalus: response to shunting and predictors of response. Neurology 2015;85:2063–71 doi:10.1212/WNL.0000000000002193 pmid:26644048

   Abstract/FREE Full Text
6. 6.↵
   1. Giordan E,
   2. Palandri G,
   3. Lanzino G, et al

   . Outcomes and complications of different surgical treatments for idiopathic normal pressure hydrocephalus: a systematic review and meta-analysis. J Neurosurg 2019;131:1024–36 doi:10.3171/2018.5.JNS1875 pmid:30497150

   CrossRefPubMed
7. 7.↵
   1. Bergsneider M,
   2. Black PML,
   3. Klinge P, et al

   . INPH guidelines, part IV: surgical management of idiopathic normal-pressure hydrocephalus. Neurosurgery 2005;57:S2-29–39 doi:10.1227/01.NEU.0000168186.45363.4D

   CrossRef
8. 8.↵
   1. Bradley WG,
   2. Kortman KE,
   3. Burgoyne B

   . Flowing cerebrospinal fluid in normal and hydrocephalic states: appearance on MR images. Radiology 1986;159:611–16 doi:10.1148/radiology.159.3.3704142 pmid:3704142

   CrossRefPubMedWeb of Science
9. 9.↵
   1. Pereira Damasceno B,
   2. Damasceno BP

   . Normal pressure hydrocephalus: diagnostic and predictive evaluation. Dement Neuropsychol 2015;9:350–55 doi:10.1590/1980-57642015DN94000350 pmid:29213984

   CrossRefPubMed
10. 10.↵
    1. Ishikawa M,
    2. Oowaki H,
    3. Takezawa M, et al

    . Disproportionately enlarged subarachnoid space hydrocephalus in idiopathic normal-pressure hydrocephalus and its implication in pathogenesis. Acta Neurochir Suppl 2016;122:287–90 doi:10.1007/978-3-319-22533-3_57 pmid:27165923

    CrossRefPubMed
11. 11.↵
    1. Craven CL,
    2. Toma AK,
    3. Mostafa T, et al

    . The predictive value of DESH for shunt responsiveness in idiopathic normal pressure hydrocephalus. J Clin Neurosci 2016;34:294–98 doi:10.1016/j.jocn.2016.09.004 pmid:27692614

    CrossRefPubMed
12. 12.↵
    1. Grahnke K,
    2. Jusue-Torres I,
    3. Szujewski C, et al

    . The quest for predicting sustained shunt response in normal-pressure hydrocephalus: an analysis of the callosal angle’s utility. World Neurosurg 2018;115:e717–22 doi:10.1016/j.wneu.2018.04.150 pmid:29723726

    CrossRefPubMed
13. 13.↵
    1. Kockum K,
    2. Virhammar J,
    3. Riklund K, et al

    . Diagnostic accuracy of the iNPH radscale in idiopathic normal pressure hydrocephalus. PLoS One 2020;15:e0232275 doi:10.1371/journal.pone.0232275 pmid:32330190

    CrossRefPubMed
14. 14.↵
    1. Kockum K,
    2. Lilja-Lund O,
    3. Larsson EM, et al

    . The idiopathic normal-pressure hydrocephalus radscale: a radiological scale for structured evaluation. Eur J Neurol 2018;25:569–76 doi:10.1111/ene.13555 pmid:29281156

    CrossRefPubMed
15. 15.↵
    1. Relkin N,
    2. Marmarou A,
    3. Klinge P, et al

    . Diagnosing idio-pathic normal-pressure hydrocephalus. Neurosurgery 2005;57(Suppl 3):S4–16 doi:10.1227/01.NEU.0000168185.29659.C5 pmid:16160425

    CrossRefPubMed
16. 16.↵
    1. Eklund A,
    2. Smielewski P,
    3. Chambers I, et al

    . Assessment of cerebrospinal fluid outflow resistance. Med Biol Eng Comput 2007;45:719–35 doi:10.1007/s11517-007-0199-5 pmid:17634761

    CrossRefPubMedWeb of Science
17. 17.↵
    1. Virhammar J,
    2. Laurell K,
    3. Cesarini KG, et al

    . The callosal angle measured on MRI as a predictor of outcome in idiopathic normal-pressure hydrocephalus. J Neurosurg 2014;120:178–84 doi:10.3171/2013.8.JNS13575 pmid:24074491

    CrossRefPubMed
18. 18.↵
    1. Virhammar J,
    2. Laurell K,
    3. Cesarini KG, et al

    . Preoperative prognostic value of MRI findings in 108 patients with idiopathic normal pressure hydrocephalus. AJNR Am J Neuroradiol 2014;35:2311–18 doi:10.3174/ajnr.A4046 pmid:25012669

    Abstract/FREE Full Text
19. 19.↵
    1. Folstein MF,
    2. Folstein SE,
    3. McHugh PR

    . “Mini-mental state”: a practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975;12:189–98 doi:10.1016/0022-3956(75)90026-6 pmid:1202204

    CrossRefPubMedWeb of Science
20. 20.↵
    1. Hellström P,
    2. Klinge P,
    3. Tans J, et al

    . A new scale for assessment of severity and outcome in iNPH. Acta Neurol Scand 2012;126:229–37 doi:10.1111/j.1600-0447.2012.01881.x pmid:22587624

    CrossRefPubMed
21. 21.↵
    1. Landis JR,
    2. Koch GG

    . The measurement of observer agreement for categorical data. Biometrics 1977;33:159–74 doi:10.2307/2529310 pmid:843571

    CrossRefPubMedWeb of Science
22. 22.↵
    1. Kuchcinski G,
    2. Jacquiez C,
    3. Baroncini M, et al

    . Idiopathic normal-pressure hydrocephalus: diagnostic accuracy of automated sulcal morphometry in patients with ventriculomegaly. Clin Neurosurg 2019;85:E747–55 doi:10.1093/neuros/nyz121 pmid:31115469

    CrossRefPubMed
23. 23.↵
    1. Hong YJ,
    2. Kim MJ,
    3. Jeong E, et al

    . Preoperative biomarkers in patients with idiopathic normal pressure hydrocephalus showing a favorable shunt surgery outcome. J Neurol Sci 2018;387:21–26 doi:10.1016/j.jns.2018.01.017 pmid:29571865

    CrossRefPubMed
24. 24.↵
    1. Kockum K,
    2. Virhammar J,
    3. Riklund K, et al

    . Standardized image evaluation in patients with idiopathic normal pressure hydrocephalus: consistency and reproducibility. Neuroradiology 2019;61:1397–406 doi:10.1007/s00234-019-02273-2 pmid:31399851

    CrossRefPubMed
25. 25.↵
    1. Laticevschi T,
    2. Lingenberg A,
    3. Armand S, et al

    . Can the radiological scale “iNPH radscale” predict tap test response in idiopathic normal pressure hydrocephalus? J Neurol Sci 2021;420:117239 doi:10.1016/j.jns.2020.117239 pmid:33278661

    CrossRefPubMed
26. 26.↵
    1. Agerskov S,
    2. Wallin M,
    3. Hellström P, et al

    . Absence of disproportionately enlarged subarachnoid space hydrocephalus, a sharp callosal angle, or other morphologic MRI markers should not be used to exclude patients with idiopathic normal pressure hydrocephalus from shunt surgery. AJNR Am J Neuroradiol 2019;40:74–79 doi:10.3174/ajnr.A5910 pmid:30523139

    Abstract/FREE Full Text
27. 27.↵
    1. Kojoukhova M,
    2. Koivisto AM,
    3. Korhonen R, et al

    . Feasibility of radiological markers in idiopathic normal pressure hydrocephalus. Acta Neurochir (Wien) 2015;157:1709–19 doi:10.1007/s00701-015-2503-8 pmid:26190755

    CrossRefPubMed
28. 28.↵
    1. Shinoda N,
    2. Hirai O,
    3. Hori S, et al

    . Utility of MRI-based disproportionately enlarged subarachnoid space hydrocephalus scoring for predicting prognosis after surgery for idiopathic normal pressure hydrocephalus: Clinical research. J Neurosurg 2017;127:1436–42 doi:10.3171/2016.9.JNS161080 pmid:28156249

    CrossRefPubMed
29. 29.↵
    1. Yamada S,
    2. Ishikawa M,
    3. Nozaki K

    . Exploring mechanisms of ventricular enlargement in idiopathic normal pressure hydrocephalus: a role of cerebrospinal fluid dynamics and motile cilia. Fluids Barriers CNS 2021;18:20 doi:10.1186/s12987-021-00243-6 pmid:33874972

    CrossRefPubMed
30. 30.↵
    1. Modesto PC,
    2. Pinto FC

    . Home physical exercise program: analysis of the impact on the clinical evolution of patients with normal pressure hydrocephalus. Arq Neuropsiquiatr 2019;77:860–70 doi:10.1590/0004-282x20190183

    CrossRef
31. 31.↵
    1. Shanks J,
    2. Markenroth Bloch K,
    3. Laurell K, et al

    . Aqueductal CSF stroke volume is increased in patients with idiopathic normal pressure hydrocephalus and decreases after shunt surgery. AJNR Am J Neuroradiol 2019;40:453–59 doi:10.3174/ajnr.A5972] pmid:30665428

    Abstract/FREE Full Text
32. 32.↵
    1. Hamilton RB,
    2. Scalzo F,
    3. Baldwin K, et al

    . Opposing CSF hydrodynamic trends found in the cerebral aqueduct and prepontine cistern following shunt treatment in patients with normal pressure hydrocephalus. Fluids Barriers CNS 2019;16:2–13 doi:10.1186/s12987-019-0122-0 pmid:30665428

    CrossRefPubMed
33. 33.↵
    1. Ziegelitz D,
    2. Starck G,
    3. Kristiansen D, et al

    . Cerebral perfusion measured by dynamic susceptibility contrast MRI is reduced in patients with idiopathic normal pressure hydrocephalus. J Magn Reson Imaging 2014;39:1533–42 doi:10.1002/jmri.24292 pmid:24006249

    CrossRefPubMed
34. 34.↵
    1. Ziegelitz D,
    2. Arvidsson J,
    3. Hellstrom P, et al

    . Pre-and postoperative cerebral blood flow changes in patients with idiopathic normal pressure hydrocephalus measured by computed tomography (CT)-perfusion. J Cereb Blood Flow Metab 2016;36:1755–66 doi:10.1177/0271678X15608521 pmid:26661191

    CrossRefPubMed
35. 35.↵
    1. Ziegelitz D,
    2. Arvidsson J,
    3. Hellström P, et al

    . In patients with idiopathic normal pressure hydrocephalus postoperative cerebral perfusion changes measured by dynamic susceptibility contrast magnetic resonance imaging correlate with clinical improvement. J Comput Assist Tomogr 2015;39:531–40 doi:10.1097/RCT.0000000000000254 pmid:25974719

    CrossRefPubMed
36. 36.↵
    1. Engel DC,
    2. Adib SD,
    3. Schuhmann MU, et al

    . Paradigm-shift: radiological changes in the asymptomatic iNPH-patient to be: An observational study. Fluids Barriers CNS 2018;15:5 doi:10.1186/s12987-018-0090-9 pmid:29422104

    CrossRefPubMed
37. 37.↵
    1. Kimihira L,
    2. Iseki C,
    3. Takahashi Y, et al

    . A multi-center, prospective study on the progression rate of asymptomatic ventriculomegaly with features of idiopathic normal pressure hydrocephalus on magnetic resonance imaging to idiopathic normal pressure hydrocephalus. J Neurol Sci 2020;419:117166 doi:10.1016/j.jns.2020.117166 pmid:33065495

    CrossRefPubMed
38. 38.↵
    1. Suehiro T,
    2. Kazui H,
    3. Kanemoto H, et al

    . Changes in brain morphology in patients in the preclinical stage of idiopathic normal pressure hydrocephalus. Psychogeriatrics 2019;19:557–65 doi:10.1111/psyg.12445 pmid:30950145

    CrossRefPubMed
39. 39.↵
    1. Czepko R,
    2. Cieslicki K

    . Repeated assessment of suspected normal pressure hydrocephalus in non-shunted cases: a prospective study based on the constant rate lumbar infusion test. Acta Neurochir (Wien) 2016;158:855–63 doi:10.1007/s00701-016-2732-5 pmid:26923798

    CrossRefPubMed
40. 40.↵
    1. Wu D,
    2. Moghekar A,
    3. Shi W, et al

    . Systematic volumetric analysis predicts response to CSF drainage and outcome to shunt surgery in idiopathic normal pressure hydrocephalus. Imaging Informatics and Artificial Intelligence. https://doi.org/10.1007/s00330-020-07531-z. Accessed March 18, 2021
41. 41.↵
    1. Rau A,
    2. Kim S,
    3. Yang S, et al

    . SVM-based normal pressure hydrocephalus detection. Clin Neuroradiol 2021 Jan 26. [Epub ahead of print] doi:10.1007/s00062-020-00993-0

    CrossRef
42. 42.↵
    1. Irie R,
    2. Otsuka Y,
    3. Hagiwara A, et al

    . A novel deep learning approach with a 3D convolutional ladder network for differential diagnosis of idiopathic normal pressure hydrocephalus and Alzheimer’s Disease. Magn Reson Med Sci 2020;19:351–58 doi:10.2463/mrms.mp.2019-0106 pmid:31969525

    CrossRefPubMed