Radiomics-Based Machine Learning for Outcome Prediction in a Multicenter Phase II Study of Programmed Death-Ligand 1 Inhibition Immunotherapy for Glioblastoma

E. George; E. Flagg; K. Chang; H.X. Bai; H.J. Aerts; M. Vallières; D.A. Reardon; R.Y. Huang

doi:10.3174/ajnr.A7488

Research ArticleAdult Brain

Radiomics-Based Machine Learning for Outcome Prediction in a Multicenter Phase II Study of Programmed Death-Ligand 1 Inhibition Immunotherapy for Glioblastoma

E. George, E. Flagg, K. Chang, H.X. Bai, H.J. Aerts, M. Vallières, D.A. Reardon and R.Y. Huang

American Journal of Neuroradiology May 2022, 43 (5) 675-681; DOI: https://doi.org/10.3174/ajnr.A7488

E. George

aFrom the Department of Radiology and Biomedical Imaging (E.G.), University of California San Francisco, San Francisco, California

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E. Flagg

bDepartment of Radiology (E.F., R.Y.H.), Brigham and Women’s Hospital, Boston, Massachusetts

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K. Chang

cMassachusetts Institute of Technology (K.C.), Cambridge, Massachusetts

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H.X. Bai

dDepartment of Diagnostic Imaging (H.X.B.), Rhode Island Hospital and Warren Alpert Medical School of Brown University, Providence, Rhode Island

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H.J. Aerts

eArtificial Intelligence in Medicine Program (H.J.A.), Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts

fDepartments of Radiation Oncology and Radiology (H.J.A.), Brigham and Women’s Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts

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M. Vallières

gDepartment of Computer Science (M.V.), Université de Sherbrooke, Sherbrooke, Quebec, Canada

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D.A. Reardon

hCenter for Neuro Oncology (D.A.R.), Dana-Farber Cancer Institute, Boston, Massachusetts

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R.Y. Huang

bDepartment of Radiology (E.F., R.Y.H.), Brigham and Women’s Hospital, Boston, Massachusetts

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E. George, E. Flagg, K. Chang, H.X. Bai, H.J. Aerts, M. Vallières, D.A. Reardon, R.Y. Huang

Radiomics-Based Machine Learning for Outcome Prediction in a Multicenter Phase II Study of Programmed Death-Ligand 1 Inhibition Immunotherapy for Glioblastoma

American Journal of Neuroradiology May 2022, 43 (5) 675-681; DOI: 10.3174/ajnr.A7488

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Radiomics-Based Machine Learning for Outcome Prediction in a Multicenter Phase II Study of Programmed Death-Ligand 1 Inhibition Immunotherapy for Glioblastoma

E. George, E. Flagg, K. Chang, H.X. Bai, H.J. Aerts, M. Vallières, D.A. Reardon, R.Y. Huang

American Journal of Neuroradiology May 2022, 43 (5) 675-681; DOI: 10.3174/ajnr.A7488

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