Comprehensive Venous Outflow Predicts Functional Outcomes in Patients with Acute Ischemic Stroke Treated by Thrombectomy

G. Adusumilli; T.D. Faizy; S. Christensen; M. Mlynash; Y. Loh; G.W. Albers; M.G. Lansberg; J. Fiehler; J.J. Heit

doi:10.3174/ajnr.A7879

Research ArticleInterventional

Comprehensive Venous Outflow Predicts Functional Outcomes in Patients with Acute Ischemic Stroke Treated by Thrombectomy

G. Adusumilli, T.D. Faizy, S. Christensen, M. Mlynash, Y. Loh, G.W. Albers, M.G. Lansberg, J. Fiehler and J.J. Heit

American Journal of Neuroradiology June 2023, 44 (6) 675-680; DOI: https://doi.org/10.3174/ajnr.A7879

G. Adusumilli

aFrom the Department of Radiology (G.A.), Massachusetts General Hospital, Boston, Massachusetts

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for G. Adusumilli

T.D. Faizy

bDepartment of Neuroradiology (T.D.F., J.F.), University of Hamburg-Eppendorf, Hamburg, Germany

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for T.D. Faizy

S. Christensen

cStanford Stroke Center (S.C., M.M., G.W.A., M.G.L.)

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

M. Mlynash

cStanford Stroke Center (S.C., M.M., G.W.A., M.G.L.)

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for M. Mlynash

Y. Loh

eComprehensive Stroke Center (Y.L.), Swedish Neuroscience Institute, Seattle, Washington

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

G.W. Albers

cStanford Stroke Center (S.C., M.M., G.W.A., M.G.L.)

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

M.G. Lansberg

cStanford Stroke Center (S.C., M.M., G.W.A., M.G.L.)

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for M.G. Lansberg

J. Fiehler

bDepartment of Neuroradiology (T.D.F., J.F.), University of Hamburg-Eppendorf, Hamburg, Germany

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for J. Fiehler

J.J. Heit

dDepartment of Radiology (J.J.H.), Stanford University, Stanford, California

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for J.J. Heit

Article
Figures & Data
Supplemental
Info & Metrics
Responses
References
PDF

Article Information

vol. 44 no. 6 675-680

DOI

https://doi.org/10.3174/ajnr.A7879

PubMed

37202117

Published By

American Journal of Neuroradiology

Print ISSN

0195-6108

Online ISSN

1936-959X

History

Received January 31, 2023
Accepted after revision April 22, 2023
Published online June 8, 2023.

Author Information

G. Adusumillia,
T.D. Faizyb,
S. Christensenc,
M. Mlynashc,
Y. Lohe,
G.W. Albersc,
M.G. Lansbergc,
J. Fiehlerb and
J.J. Heitd

^aFrom the Department of Radiology (G.A.), Massachusetts General Hospital, Boston, Massachusetts
^bDepartment of Neuroradiology (T.D.F., J.F.), University of Hamburg-Eppendorf, Hamburg, Germany
^cStanford Stroke Center (S.C., M.M., G.W.A., M.G.L.)
^dDepartment of Radiology (J.J.H.), Stanford University, Stanford, California
^eComprehensive Stroke Center (Y.L.), Swedish Neuroscience Institute, Seattle, Washington

Please address correspondence to Jeremy Heit, MD, PhD, Center for Academic Medicine, Department of Radiology, MC:5659, 453 Quarry Rd, Palo Alto, CA 94304; e-mail: jheit{at}stanford.edu; @JeremyHeitMDPHD

View Full Text

Altmetrics

Cited By...

19 Citations
Google Scholar

This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

Decreased Quantitative Cerebral Blood Volume Is Associated With Poor Outcomes in Large Core Patients

Vivek Yedavalli, Hamza Adel Salim, Janet Mei, Dhairya A. Lakhani, Aneri Balar, Basel Musmar, Nimer Adeeb, Meisam Hoseinyazdi, Licia Luna, Francis Deng, Nathan Z. Hyson, Adam A. Dmytriw, Adrien Guenego, Tobias D. Faizy, Jeremy J. Heit, Gregory W. Albers, Hanzhang Lu, Victor C. Urrutia, Kambiz Nael, Elisabeth B. Marsh, Argye E. Hillis, Raf Llinas

Stroke 2024 55 10
Prolonged venous transit on perfusion imaging is associated with higher odds of mortality in successfully reperfused patients with large vessel occlusion stroke

Vivek S Yedavalli, Manisha Koneru, Meisam Hoseinyazdi, Cynthia Greene, Dhairya A Lakhani, Risheng Xu, Licia P Luna, Justin M Caplan, Adam A Dmytriw, Adrien Guenego, Jeremy J Heit, Gregory W Albers, Max Wintermark, L Fernando Gonzalez, Victor C Urrutia, Judy Huang, Kambiz Nael, Richard Leigh, Elisabeth B Marsh, Argye E Hillis, Rafael H Llinas

Journal of NeuroInterventional Surgery 2025 17 3
Prolonged venous transit is associated with worse neurological recovery in successfully reperfused large vessel strokes

Janet Mei, Hamza Adel Salim, Dhairya A. Lakhani, Licia Luna, Aneri Balar, Mona Shahriari, Nathan Z. Hyson, Francis Deng, Adam A. Dmytriw, Adrien Guenego, Vaibhav Vagal, Victor C. Urrutia, Elisabeth B. Marsh, Hanzhang Lu, Risheng Xu, Rich Leigh, Dylan Wolman, Gaurang Shah, Benjamin Pulli, Kambiz Nael, Gregory W. Albers, Max Wintermark, Jeremy J. Heit, Tobias D. Faizy, Argye E. Hillis, Raf Llinas, Vivek Yedavalli

Annals of Clinical and Translational Neurology 2025 12 1
Exploring the Limits of Endovascular Therapy for Large Core Patients: Where Do We Need More Data?

Gregory W. Albers, Jeremy J. Heit, Maarten G. Lansberg, Manabu Inoue, Xiaochuan Huo, Vivek S. Yedavalli, Pierre Seners, Margy McCullough-Hicks, Carlo W. Cereda, Jenny P. Tsai, Eva A. Mistry, Arindam R. Chatterjee, Colin P. Derdeyn, Pooja Khatri, J.M. Olivot, Michael D. Hill, Jeffrey L. Saver, Marc Fisher

Stroke 2024 55 7
Prolonged Venous Transit Is Associated With Lower Likelihood of Favorable Clinical Recovery in Reperfused Anterior Circulation Large‐Vessel Occlusion Stroke

Vivek S. Yedavalli, Manisha Koneru, Aneri B. Balar, Dhairya A. Lakhani, Andrew Cho, Sijin Wen, Yanqing Mei, Meisam Hoseinyazdi, Cynthia Greene, Risheng Xu, Licia P Luna, Justin M. Caplan, Adam A. Dmytriw, Adrien Guenego, Jeremy J Heit, Gregory W. Albers, Max Wintermark, Luis Fernando Gonzalez, Victor C. Urrutia, Judy Huang, Kambiz Nael, Tobias D. Faizy, Richard Leigh, Elisabeth B. Marsh, Argye E. Hillis, Rafael H. Llinas

Stroke: Vascular and Interventional Neurology 2024 4 5
Prolonged venous transit is associated with lower odds of excellent recovery after reperfusion in anterior large‐vessel occlusion stroke

Hamza Adel Salim, Dhairya A. Lakhani, Janet Mei, Licia Luna, Mona Shahriari, Nathan Z. Hyson, Francis Deng, Adam A. Dmytriw, Adrien Guenego, Victor C. Urrutia, Elisabeth B. Marsh, Hanzhang Lu, Risheng Xu, Rich Leigh, Dylan Wolman, Gaurang Shah, Benjamin Pulli, Gregory W. Albers, Argye E. Hillis, Rafael Llinas, Kambiz Nael, Max Wintermark, Jeremy J. Heit, Tobias D. Faizy, Vivek Yedavalli

European Journal of Neurology 2025 32 1
Perfusion imaging predicts short‐term clinical outcome in isolated posterior cerebral artery occlusion stroke

Hamza Adel Salim, Shenwen Huang, Dhairya A. Lakhani, Janet Mei, Aneri Balar, Basel Musmar, Nimer Adeeb, Meisam Hoseinyazdi, Licia Luna, Francis Deng, Nathan Z. Hyson, Mona Bahouth, Adam A. Dmytriw, Adrien Guenego, Gregory W. Albers's, Hanzhang Lu, Victor C. Urrutia, Kambiz Nael, Elisabeth B Marsh, Argye E. Hillis, Raf Llinas, Max Wintermark, Jeremy J. Heit, Tobias D. Faizy, Vivek Yedavalli

Journal of Neuroimaging 2024 34 6
The benefit of favorable venous outflow profile is mediated through reduced microvascular dysfunction in acute ischemic stroke

Siyuan Li, Lan Hong, Wenhao Yang, Xinyu Liu, Yiran Zhang, Yifeng Ling, Zhijiao He, Xinru Wang, Yunhua Yue, Qiang Dong, Feng Wang, Xin Cheng, Cheng Xin, Wang Feng, Yue Yunhua, Guo Ying, Lu Guozhi, Zhang Jin, Wang Ziran, Zhou Xiaoyu, Wu Danhong, Zhai Qijin, Fang Qi, Tang Ying, Zou Xin, Fan Bosheng, Qu Rongbo

European Stroke Journal 2024 9 2
Synchronous Superficial Middle Cerebral Vein Outflow Correlates Favorable Tissue Fate After Mechanical Thrombectomy for Acute Ischemic Stroke

Lisong Dai, Zheng Sun, Jingxuan Jiang, Jianyong Wei, Xinyu Song, Shen Chen, Yuehua Li

Academic Radiology 2024 31 4
A comparison of endovascular therapy and medical management in patients with large vessel occlusion mild stroke treated between 2015 and 2023: a systematic review and meta-analysis

Yiqiao Xu, Xin Liu, Hao Li

Journal of Stroke and Cerebrovascular Diseases 2024 33 7
Asymmetric deep cerebral venous filling predicts poor outcome of acute basilar artery occlusion after endovascular treatment

Huiyuan Wang, Panpan Shen, Xinyue Yu, Yafei Shang, Jie Xu, Xinyi Chen, Mingming Tan, Longting Lin, Mark Parsons, Sheng Zhang, Yu Geng

CNS Neuroscience & Therapeutics 2024 30 4
Collateral blood vessels in stroke and ischemic disease: Formation, physiology, rarefaction, remodeling

James E Faber

Journal of Cerebral Blood Flow & Metabolism 2025
Deep venous outflow as a surrogate for collaterals in late-window patients with successful revascularization from the DEFUSE 3 cohort

Gautam Adusumilli, Tobias D. Faizy, Soren Christensen, Michael Mlynash, Yince Loh, Gregory W. Albers, Maarten G. Lansberg, Jens Fiehler, Jeremy J. Heit

Interventional Neuroradiology 2024
Evaluation of cortical venous drainage in patients with Acute Ischemic Stroke

Runyang Li, Xi Li, Jie Li, Xinjun Dai, Junhong Guo, Shaoshuai Wang

Frontiers in Neuroscience 2025 19
Poor venous outflow is associated with hyperintense acute reperfusion marker on follow-up MRI in patients with acute ischemic stroke with a large vessel occlusion

Aroosa Zamarud, Nicole Yuen, Anke Wouters, Michael Mlynash, Stephen M Hugdal, Pierre Seners, Jamie Kesten, Vivek Yedavalli, Tobias D Faizy, Gregory W Albers, Maarten G Lansberg, Jeremy J Heit

Journal of NeuroInterventional Surgery 2024
Prolonged Venous Transit Independently Predicts Worse Functional Outcomes at Discharge in Successfully Reperfused Patients with Large Vessel Occlusion Stroke

Janet Mei, Hamza A. Salim, Dhairya A. Lakhani, Aneri Balar, Adam A. Dmytriw, Meisam Hoseinyazdi, Licia Luna, Francis Deng, Vaibhav Vagal, Nathan Z. Hyson, Adrien Guenego, Gregory W. Albers, Hanzhang Lu, Victor C. Urrutia, Kambiz Nael, Elisabeth B. Marsh, Argye E. Hillis, Raf Llinas, Max Wintermark, Jeremy J. Heit, Tobias D. Faizy, Vivek Yedavalli

Clinical Neuroradiology 2025
Prolonged Venous Transit as a Superior Predictor of Functional Outcomes in Successfully Reperfused Large Vessel Occlusions: Comparative Analysis With Cerebral Blood Volume Index and Hypoperfusion Intensity Ratio

Janet Mei, Hamza Adel Salim, Dhairya A. Lakhani, Aneri Balar, Vaibhav Vagal, Manisha Koneru, Dylan Wolman, Risheng Xu, Victor Urrutia, Elisabeth Breese Marsh, Benjamin Pulli, Meisam Hoseinyazdi, Licia Luna, Francis Deng, Nathan Z. Hyson, Mona Shahriari, Adam A. Dmytriw, Adrien Guenego, Gregory W. Albers, Hanzhang Lu, Kambiz Nael, Argye E. Hillis, Rafael Llinas, Max Wintermark, Tobias D. Faizy, Jeremy J. Heit, Vivek Yedavalli

Journal of the American Heart Association 2025 14 8
Role and Prognostic Implications of Venous Outflow Assessment in Acute Ischemic Stroke

Maggie Barghash, Hamza Adel Salim, Janet Mei, Mohamed Tantawi, Awab K. Elnaeem, Heitor Cabral Frade, Khalid Kabeel, Dhairya A. Lakhani, Manisha Koneru, Argye E. Hillis, Raf Llinas, Hanzhang Lu, Rich Leigh, Mona Bahouth, Victor C. Urrutia, Elisabeth B. Marsh, Risheng Xu, Judy Huang, Max Wintermark, Kambiz Nael, Gregory W. Albers, Paul Stracke, Tobias D. Faizy, Jeremy J. Heit, Vivek Yedavalli

Journal of Neuroimaging 2025 35 1
Venöse Drainage beim akuten ischämischen Schlaganfall

Neuroradiologie Scan 2023 13 04

PreviousNext

In this issue

American Journal of Neuroradiology

Vol. 44, Issue 6

1 Jun 2023

Table of Contents
Index by author
Complete Issue (PDF)

Download PDF

Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Your Email *

Your Name *

Send To *

Enter multiple addresses on separate lines or separate them with commas.

You are going to email the following Comprehensive Venous Outflow Predicts Functional Outcomes in Patients with Acute Ischemic Stroke Treated by Thrombectomy

Message Subject (Your Name) has sent you a message from American Journal of Neuroradiology

Message Body (Your Name) thought you would like to see the American Journal of Neuroradiology web site.

Your Personal Message

CAPTCHA

This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

Cite this article

G. Adusumilli, T.D. Faizy, S. Christensen, M. Mlynash, Y. Loh, G.W. Albers, M.G. Lansberg, J. Fiehler, J.J. Heit

Comprehensive Venous Outflow Predicts Functional Outcomes in Patients with Acute Ischemic Stroke Treated by Thrombectomy

American Journal of Neuroradiology Jun 2023, 44 (6) 675-680; DOI: 10.3174/ajnr.A7879

Citation Manager Formats

BibTeX
Bookends
EasyBib
EndNote (tagged)
EndNote 8 (xml)
Medlars
Mendeley
Papers
RefWorks Tagged
Ref Manager
RIS
Zotero

0 Responses

Respond to this article

Bookmark this article

User Name *

Password *

Remember my user name & password.

Venous Outflow Predicts Stroke Treatment Outcomes

G. Adusumilli, T.D. Faizy, S. Christensen, M. Mlynash, Y. Loh, G.W. Albers, M.G. Lansberg, J. Fiehler, J.J. Heit

American Journal of Neuroradiology Jun 2023, 44 (6) 675-680; DOI: 10.3174/ajnr.A7879

Share This Article:

Tweet Widget
Facebook Like
Google Plus One

Purchase

Jump to section

Article
Figures & Data
Supplemental
Info & Metrics
Responses
References
PDF

PubMed
Google Scholar

Cited By...

Prolonged venous transit on perfusion imaging is associated with higher odds of mortality in successfully reperfused patients with large vessel occlusion stroke
Poor venous outflow is associated with hyperintense acute reperfusion marker on follow-up MRI in patients with acute ischemic stroke with a large vessel occlusion

Crossref (19)
Google Scholar

This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

Decreased Quantitative Cerebral Blood Volume Is Associated With Poor Outcomes in Large Core Patients

Vivek Yedavalli, Hamza Adel Salim, Janet Mei, Dhairya A. Lakhani, Aneri Balar, Basel Musmar, Nimer Adeeb, Meisam Hoseinyazdi, Licia Luna, Francis Deng, Nathan Z. Hyson, Adam A. Dmytriw, Adrien Guenego, Tobias D. Faizy, Jeremy J. Heit, Gregory W. Albers, Hanzhang Lu, Victor C. Urrutia, Kambiz Nael, Elisabeth B. Marsh, Argye E. Hillis, Raf Llinas

Stroke 2024 55 10
Prolonged venous transit on perfusion imaging is associated with higher odds of mortality in successfully reperfused patients with large vessel occlusion stroke

Vivek S Yedavalli, Manisha Koneru, Meisam Hoseinyazdi, Cynthia Greene, Dhairya A Lakhani, Risheng Xu, Licia P Luna, Justin M Caplan, Adam A Dmytriw, Adrien Guenego, Jeremy J Heit, Gregory W Albers, Max Wintermark, L Fernando Gonzalez, Victor C Urrutia, Judy Huang, Kambiz Nael, Richard Leigh, Elisabeth B Marsh, Argye E Hillis, Rafael H Llinas

Journal of NeuroInterventional Surgery 2025 17 3
Prolonged venous transit is associated with worse neurological recovery in successfully reperfused large vessel strokes

Janet Mei, Hamza Adel Salim, Dhairya A. Lakhani, Licia Luna, Aneri Balar, Mona Shahriari, Nathan Z. Hyson, Francis Deng, Adam A. Dmytriw, Adrien Guenego, Vaibhav Vagal, Victor C. Urrutia, Elisabeth B. Marsh, Hanzhang Lu, Risheng Xu, Rich Leigh, Dylan Wolman, Gaurang Shah, Benjamin Pulli, Kambiz Nael, Gregory W. Albers, Max Wintermark, Jeremy J. Heit, Tobias D. Faizy, Argye E. Hillis, Raf Llinas, Vivek Yedavalli

Annals of Clinical and Translational Neurology 2025 12 1
Exploring the Limits of Endovascular Therapy for Large Core Patients: Where Do We Need More Data?

Gregory W. Albers, Jeremy J. Heit, Maarten G. Lansberg, Manabu Inoue, Xiaochuan Huo, Vivek S. Yedavalli, Pierre Seners, Margy McCullough-Hicks, Carlo W. Cereda, Jenny P. Tsai, Eva A. Mistry, Arindam R. Chatterjee, Colin P. Derdeyn, Pooja Khatri, J.M. Olivot, Michael D. Hill, Jeffrey L. Saver, Marc Fisher

Stroke 2024 55 7
Prolonged Venous Transit Is Associated With Lower Likelihood of Favorable Clinical Recovery in Reperfused Anterior Circulation Large‐Vessel Occlusion Stroke

Vivek S. Yedavalli, Manisha Koneru, Aneri B. Balar, Dhairya A. Lakhani, Andrew Cho, Sijin Wen, Yanqing Mei, Meisam Hoseinyazdi, Cynthia Greene, Risheng Xu, Licia P Luna, Justin M. Caplan, Adam A. Dmytriw, Adrien Guenego, Jeremy J Heit, Gregory W. Albers, Max Wintermark, Luis Fernando Gonzalez, Victor C. Urrutia, Judy Huang, Kambiz Nael, Tobias D. Faizy, Richard Leigh, Elisabeth B. Marsh, Argye E. Hillis, Rafael H. Llinas

Stroke: Vascular and Interventional Neurology 2024 4 5
Prolonged venous transit is associated with lower odds of excellent recovery after reperfusion in anterior large‐vessel occlusion stroke

Hamza Adel Salim, Dhairya A. Lakhani, Janet Mei, Licia Luna, Mona Shahriari, Nathan Z. Hyson, Francis Deng, Adam A. Dmytriw, Adrien Guenego, Victor C. Urrutia, Elisabeth B. Marsh, Hanzhang Lu, Risheng Xu, Rich Leigh, Dylan Wolman, Gaurang Shah, Benjamin Pulli, Gregory W. Albers, Argye E. Hillis, Rafael Llinas, Kambiz Nael, Max Wintermark, Jeremy J. Heit, Tobias D. Faizy, Vivek Yedavalli

European Journal of Neurology 2025 32 1
Perfusion imaging predicts short‐term clinical outcome in isolated posterior cerebral artery occlusion stroke

Hamza Adel Salim, Shenwen Huang, Dhairya A. Lakhani, Janet Mei, Aneri Balar, Basel Musmar, Nimer Adeeb, Meisam Hoseinyazdi, Licia Luna, Francis Deng, Nathan Z. Hyson, Mona Bahouth, Adam A. Dmytriw, Adrien Guenego, Gregory W. Albers's, Hanzhang Lu, Victor C. Urrutia, Kambiz Nael, Elisabeth B Marsh, Argye E. Hillis, Raf Llinas, Max Wintermark, Jeremy J. Heit, Tobias D. Faizy, Vivek Yedavalli

Journal of Neuroimaging 2024 34 6
The benefit of favorable venous outflow profile is mediated through reduced microvascular dysfunction in acute ischemic stroke

Siyuan Li, Lan Hong, Wenhao Yang, Xinyu Liu, Yiran Zhang, Yifeng Ling, Zhijiao He, Xinru Wang, Yunhua Yue, Qiang Dong, Feng Wang, Xin Cheng, Cheng Xin, Wang Feng, Yue Yunhua, Guo Ying, Lu Guozhi, Zhang Jin, Wang Ziran, Zhou Xiaoyu, Wu Danhong, Zhai Qijin, Fang Qi, Tang Ying, Zou Xin, Fan Bosheng, Qu Rongbo

European Stroke Journal 2024 9 2
Synchronous Superficial Middle Cerebral Vein Outflow Correlates Favorable Tissue Fate After Mechanical Thrombectomy for Acute Ischemic Stroke

Lisong Dai, Zheng Sun, Jingxuan Jiang, Jianyong Wei, Xinyu Song, Shen Chen, Yuehua Li

Academic Radiology 2024 31 4
A comparison of endovascular therapy and medical management in patients with large vessel occlusion mild stroke treated between 2015 and 2023: a systematic review and meta-analysis

Yiqiao Xu, Xin Liu, Hao Li

Journal of Stroke and Cerebrovascular Diseases 2024 33 7

Main menu

User menu

Search

American Journal of Neuroradiology

Comprehensive Venous Outflow Predicts Functional Outcomes in Patients with Acute Ischemic Stroke Treated by Thrombectomy

Article Information

Author Information

Altmetrics

Cited By...

In this issue

Citation Manager Formats

Related Articles

Cited By...

More in this TOC Section

Similar Articles

Indexed Content

Cases

Special Collections

Resources

Multimedia

About Us

American Society of Neuroradiology