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History
- Received May 6, 2024
- Accepted after revision June 22, 2024
- Published online December 9, 2024.
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© 2024 by American Journal of Neuroradiology
Author Information
- Benjamin M. Ellingsona,
- Francesco Sanvitoa,
- Timothy F. Cloughesyb,
- Raymond Y. Huangc,
- Javier E. Villanueva-Meyerd,
- Whitney B. Popew,
- Daniel P. Barboriake,
- Lalitha K. Shankarf,
- Marion Smitsg,
- Timothy J. Kaufmannh,
- Jerrold L. Boxermani,
- Michael Wellerj,
- Evanthia Galanisk,
- John de Grootl,
- Mark R. Gilbertm,
- Andrew B. Lassmann,
- Mark S. Shiroishio,
- Ali Nabavizadehp,
- Minesh Mehtaq,
- Roger Stuppr,
- Wolfgang Wicks,
- David A. Reardont,
- Michael A. Vogelbaumu,
- Martin van den Bentv,
- Susan M. Changl and
- Patrick Y. Went
- aFrom the UCLA Brain Tumor Imaging Laboratory, Department of Radiological Sciences (B.M.E., F.S.), David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA
- bUCLA Brain Tumor Program, Department of Neurology (T.F.C.), David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA
- cDepartment of Radiology, Brigham and Women's Hospital (R.Y.H.), Harvard Medical School, Boston, MA
- dDepartments of Radiology and Neurosurgery (J.E.V.-M.), University of California San Francisco, CA
- eDepartment of Radiology (D.P.B.), Duke University Medical Center, Durham, NC
- fClinical Trials Branch, Cancer Imaging Program (L.K.S.), National Cancer Institute, National Institutes of Health, Bethesda, MD
- gDepartment of Radiology & Nuclear Medicine (M.S.), Erasmus MC - University Medical Centre Rotterdam, Rotterdam, The Netherlands
- hDepartment of Radiology (T.J.K.), Mayo Clinic, Rochester, MN
- iDepartment of Diagnostic Imaging (J.L.B.), Rhode Island Hospital and Alpert Medical School of Brown University, Providence, RI
- jDepartment of Neurology (M.W.), University Hospital and University of Zurich, Zurich, Switzerland
- kDepartment of Oncology (E.G.), Mayo Clinic, Rochester, MN
- lDivision of Neuro-Oncology, Department of Neurosurgery (J.d.G., S.M.C.), University of California, San Francisco, CA
- mNeuro-Oncology Branch, Center for Cancer Research (M.R.G.), National Cancer Institute, National Institutes of Health, Bethesda, MD
- nDivision of Neuro-Oncology, Department of Neurology (A.B.L.), Herbert Irving Comprehensive Cancer Center and Irving Institute for Clinical and Translational Research, Columbia University Vagelos College of Physicians and Surgeons and New York-Presbyterian Hospital, New York, NY
- oDepartment of Radiology (M.S.S.), Keck School of Medicine of the University of Southern California (USC), Los Angeles, CA
- pDepartment of Radiology (A.N.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
- qMiami Cancer Institute (M.M.), Miami, FL
- rMalnati Brain Tumor Institute, Lurie Comprehensive Cancer Center and Departments of Neurological Surgery, Neurology and Division of Hematology/Oncology (R.S.), Northwestern University, Chicago, IL
- sDepartment of Neurology Heidelberg University Hospital & Clinical Cooperation Unit Neurooncology (W.W.), German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany
- tCenter For Neuro-Oncology, Dana-Farber Cancer Institute and Harvard Medical School(D.A.R., P.Y.W.), Boston, MA
- uDepartment of Neuro-Oncology (M.A.V.), Moffitt Cancer Center, Tampa, FL
- vDepartment Neuro-Oncology (M.v.d.B.), Erasmus MC Cancer Institute, Rotterdam, The Netherlands
- wDepartment of Radiological Sciences (W.B.P.), David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA
- Corresponding Author: Benjamin M. Ellingson, Ph.D. Professor and Director of MRI Research, Director, UCLA Brain Tumor Imaging Laboratory, UCLA Radiology, e-mail: bellingson{at}mednet.ucla.edu
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- Article
- Graphical Abstract
- Abstract
- ABBREVIATIONS:
- STANDARDIZED BRAIN TUMOR IMAGING PROTOCOL (BTIP) AND RADIOGRAPHIC READ PARADIGMS
- OVERVIEW OF UPDATES IN RANO 2.0
- DEFINITIONS OF MEASURABLE, NON-MEASURABLE, AND TARGET LESIONS (FIGURE 1)
- METHODOLOGY FOR 2D MEASUREMENTS (FIGURE 2)
- STEP-BY-STEP GUIDE TO RANO 2.0 RADIOGRAPHIC READS
- ADDITIONAL NOTES ON THE EVALUATION OF CE AND NON-CE DISEASE
- CORRESPONDENCE BETWEEN 2D AND 3D MEASUREMENTS
- CLINICAL DETERIORATION AND CORTICOSTEROID USE
- CONCLUSIONS
- Footnotes
- REFERENCES
- Figures & Data
- Supplemental
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- References