Imaging Biomarker for Early-Stage Alzheimer Disease: Utility of Hippocampal Histogram Analysis of Diffusion Metrics

Hiroto Takahashi; Yoichi Takami; Shuko Takeda; Naoki Hayakawa; Tsuneo Nakajima; Yasushi Takeya; Chisato Matsuo-Hagiyama; Atsuko Arisawa; Hiromi Rakugi; Noriyuki Tomiyama

doi:10.3174/ajnr.A8106

Research ArticleNeurodegenerative Disorder Imaging

Imaging Biomarker for Early-Stage Alzheimer Disease: Utility of Hippocampal Histogram Analysis of Diffusion Metrics

Hiroto Takahashi, Yoichi Takami, Shuko Takeda, Naoki Hayakawa, Tsuneo Nakajima, Yasushi Takeya, Chisato Matsuo-Hagiyama, Atsuko Arisawa, Hiromi Rakugi and Noriyuki Tomiyama

American Journal of Neuroradiology March 2024, 45 (3) 320-327; DOI: https://doi.org/10.3174/ajnr.A8106

Hiroto Takahashi

aFrom the Department of Diagnostic and Interventional Radiology (H.T., C.M.-H., A.A., N.T.), Osaka University Graduate School of Medicine, Suita, Osaka, Japan

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Yoichi Takami

bDepartment of Geriatric and General Medicine (Y. Takami, N.H., T.N., Y. Takeya, H.R.), Osaka University Graduate School of Medicine, Suita, Osaka, Japan

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Shuko Takeda

cDepartment of Clinical Gene Therapy, Graduate School of Medicine (S.T.), Osaka University, Suita, Osaka, Japan

dOsaka Psychiatric Research Center (S.T.), Osaka Psychiatric Medical Center, Hirakata, Osaka, Japan

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Naoki Hayakawa

bDepartment of Geriatric and General Medicine (Y. Takami, N.H., T.N., Y. Takeya, H.R.), Osaka University Graduate School of Medicine, Suita, Osaka, Japan

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Tsuneo Nakajima

bDepartment of Geriatric and General Medicine (Y. Takami, N.H., T.N., Y. Takeya, H.R.), Osaka University Graduate School of Medicine, Suita, Osaka, Japan

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Yasushi Takeya

bDepartment of Geriatric and General Medicine (Y. Takami, N.H., T.N., Y. Takeya, H.R.), Osaka University Graduate School of Medicine, Suita, Osaka, Japan

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Chisato Matsuo-Hagiyama

aFrom the Department of Diagnostic and Interventional Radiology (H.T., C.M.-H., A.A., N.T.), Osaka University Graduate School of Medicine, Suita, Osaka, Japan

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Atsuko Arisawa

aFrom the Department of Diagnostic and Interventional Radiology (H.T., C.M.-H., A.A., N.T.), Osaka University Graduate School of Medicine, Suita, Osaka, Japan

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Hiromi Rakugi

bDepartment of Geriatric and General Medicine (Y. Takami, N.H., T.N., Y. Takeya, H.R.), Osaka University Graduate School of Medicine, Suita, Osaka, Japan

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Noriyuki Tomiyama

aFrom the Department of Diagnostic and Interventional Radiology (H.T., C.M.-H., A.A., N.T.), Osaka University Graduate School of Medicine, Suita, Osaka, Japan

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Vol. 45, Issue 3

1 Mar 2024

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Cite this article

Hiroto Takahashi, Yoichi Takami, Shuko Takeda, Naoki Hayakawa, Tsuneo Nakajima, Yasushi Takeya, Chisato Matsuo-Hagiyama, Atsuko Arisawa, Hiromi Rakugi, Noriyuki Tomiyama

Imaging Biomarker for Early-Stage Alzheimer Disease: Utility of Hippocampal Histogram Analysis of Diffusion Metrics

American Journal of Neuroradiology Mar 2024, 45 (3) 320-327; DOI: 10.3174/ajnr.A8106

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Hippocampal Histogram Analysis for Early Alzheimer

Hiroto Takahashi, Yoichi Takami, Shuko Takeda, Naoki Hayakawa, Tsuneo Nakajima, Yasushi Takeya, Chisato Matsuo-Hagiyama, Atsuko Arisawa, Hiromi Rakugi, Noriyuki Tomiyama

American Journal of Neuroradiology Mar 2024, 45 (3) 320-327; DOI: 10.3174/ajnr.A8106

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