Identification of Multiclass Pediatric Low-Grade Neuroepithelial Tumor Molecular Subtype with ADC MR Imaging and Machine Learning

Matheus D. Soldatelli; Khashayar Namdar; Uri Tabori; Cynthia Hawkins; Kristen Yeom; Farzad Khalvati; Birgit B. Ertl-Wagner; Matthias W. Wagner

doi:10.3174/ajnr.A8199

Research ArticlePediatric Neuroimaging

Identification of Multiclass Pediatric Low-Grade Neuroepithelial Tumor Molecular Subtype with ADC MR Imaging and Machine Learning

Matheus D. Soldatelli, Khashayar Namdar, Uri Tabori, Cynthia Hawkins, Kristen Yeom, Farzad Khalvati, Birgit B. Ertl-Wagner and Matthias W. Wagner

American Journal of Neuroradiology June 2024, 45 (6) 753-760; DOI: https://doi.org/10.3174/ajnr.A8199

Matheus D. Soldatelli

aFrom the Department Diagnostic Imaging (M.D.S., B.B.E.-W., M.W.W.), Division of Neuroradiology, The Hospital for Sick Children, Toronto, Ontario, Canada

bDepartment of Medical Imaging (M.D.S., K.N., F.K., B.B.E.-W., M.W.W.), University of Toronto, Toronto, Ontario, Canada

cInstitute of Medical Science (M.D.S., K.N., U.T., F.K., B.B.E.-W.), University of Toronto, Toronto, Ontario, Canada

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Khashayar Namdar

bDepartment of Medical Imaging (M.D.S., K.N., F.K., B.B.E.-W., M.W.W.), University of Toronto, Toronto, Ontario, Canada

cInstitute of Medical Science (M.D.S., K.N., U.T., F.K., B.B.E.-W.), University of Toronto, Toronto, Ontario, Canada

dVector Institute (K.N., F.K.), Toronto, Ontario, Canada

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Uri Tabori

cInstitute of Medical Science (M.D.S., K.N., U.T., F.K., B.B.E.-W.), University of Toronto, Toronto, Ontario, Canada

eThe Arthur and Sonia Labatt Brain Tumour Research Centre (U.T., C.H.), The Hospital for Sick Children, Toronto, Ontario, Canada

fProgram in Genetics and Genome Biology (U.T.) The Hospital for Sick Children, Toronto, Ontario, Canada

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Cynthia Hawkins

eThe Arthur and Sonia Labatt Brain Tumour Research Centre (U.T., C.H.), The Hospital for Sick Children, Toronto, Ontario, Canada

gDepartment of Laboratory Medicine and Pathobiology (C.H.), University of Toronto, Toronto, Ontario, Canada

hDivision of Pathology (C.H.), The Hospital for Sick Children, Toronto, Ontario, Canada

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Kristen Yeom

iDepartment of Radiology (K.Y.), Lucile Packard Children's Hospital, Stanford University School of Medicine, Stanford, California

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Farzad Khalvati

bDepartment of Medical Imaging (M.D.S., K.N., F.K., B.B.E.-W., M.W.W.), University of Toronto, Toronto, Ontario, Canada

cInstitute of Medical Science (M.D.S., K.N., U.T., F.K., B.B.E.-W.), University of Toronto, Toronto, Ontario, Canada

dVector Institute (K.N., F.K.), Toronto, Ontario, Canada

jDepartment of Computer Science (F.K.), University of Toronto, Toronto, Ontario, Canada

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Birgit B. Ertl-Wagner

aFrom the Department Diagnostic Imaging (M.D.S., B.B.E.-W., M.W.W.), Division of Neuroradiology, The Hospital for Sick Children, Toronto, Ontario, Canada

bDepartment of Medical Imaging (M.D.S., K.N., F.K., B.B.E.-W., M.W.W.), University of Toronto, Toronto, Ontario, Canada

cInstitute of Medical Science (M.D.S., K.N., U.T., F.K., B.B.E.-W.), University of Toronto, Toronto, Ontario, Canada

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Matthias W. Wagner

aFrom the Department Diagnostic Imaging (M.D.S., B.B.E.-W., M.W.W.), Division of Neuroradiology, The Hospital for Sick Children, Toronto, Ontario, Canada

bDepartment of Medical Imaging (M.D.S., K.N., F.K., B.B.E.-W., M.W.W.), University of Toronto, Toronto, Ontario, Canada

kDepartment of Diagnostic and Interventional Neuroradiology (M.W.W.), University Hospital Augsburg, Augsburg, Germany

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Matheus D. Soldatelli, Khashayar Namdar, Uri Tabori, Cynthia Hawkins, Kristen Yeom, Farzad Khalvati, Birgit B. Ertl-Wagner, Matthias W. Wagner

Identification of Multiclass Pediatric Low-Grade Neuroepithelial Tumor Molecular Subtype with ADC MR Imaging and Machine Learning

American Journal of Neuroradiology Jun 2024, 45 (6) 753-760; DOI: 10.3174/ajnr.A8199

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PEDS Low-Grade Neuroepithelial Tumor Subtypes

Matheus D. Soldatelli, Khashayar Namdar, Uri Tabori, Cynthia Hawkins, Kristen Yeom, Farzad Khalvati, Birgit B. Ertl-Wagner, Matthias W. Wagner

American Journal of Neuroradiology Jun 2024, 45 (6) 753-760; DOI: 10.3174/ajnr.A8199

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