Research ArticleNeurointervention
Predictors of Aneurysm Obliteration in Patients Treated with the WEB Device: Results of a Multicenter Retrospective Study
Panagiotis Mastorakos, Kareem El Naamani, Nimer Adeeb, Mathews Lan, James Castiglione, Omaditya Khanna, Ritam Ghosh, Jose Danilo Bengzon Diestro, Mahmoud Dibas, Rachel M. McLellan, Oktay Algin, Sherief Ghozy, Nicole M. Cancelliere, Assala Aslan, Hugo H. Cuellar-Saenz, Sovann V. Lay, Adrien Guenego, Leonardo Renieri, Joseph Carnevale, Guillaume Saliou, Eimad Shotar, Kevin Premat, Markus Möhlenbruch, Michael Kral, Justin E. Vranic, Charlotte Chung, Mohamed M. Salem, Ivan Lylyk, Paul M. Foreman, Jay A. Vachhani, Hamza Shaikh, Vedran Župančić, Muhammad U. Hafeez, Joshua Catapano, Muhammad Waqas, Vincent M. Tutino, Mohamed K. Ibrahim, Marwa A. Mohammed, James D. Rabinov, Yifan Ren, Clemens M. Schirmer, Mariangela Piano, Maria Bres Bullrich, Michael Mayich, Anna L. Kühn, Caterina Michelozzi, Stéphanie Elens, Robert M. Starke, Ameer E. Hassan, Mark Ogilvie, Anh Nguyen, Jesse Jones, Waleed Brinjikji, Marios Psychogios, Christian Ulfert, Julian Spears, Brian T. Jankowitz, Jan-Karl Burkhardt, Ricardo A. Domingo, Thien Huynh, Rabih G. Tawk, Boris Lubicz, Marie T. Nawka, Pietro Panni, Ajit S. Puri, Guglielmo Pero, Erez Nossek, Eytan Raz, Monika Killer-Oberpfalzer, M. Ozgur Ozates, Giyas Ayberk, Robert W. Regenhardt, Christoph J. Griessenauer, Hamed Asadi, Adnan Siddiqui, Andrew F. Ducruet, Felipe C. Albuquerque, Nirav J. Patel, Christopher J. Stapleton, Peter Kan, Vladimir Kalousek, Pedro Lylyk, Srikanth Boddu, Jared Knopman, Mohammad A. Aziz-Sultan, Frédéric Clarençon, Nicola Limbucci, Mario Zanaty, Juan Carlos Martinez-Gutierrez, Sunil Sheth, Gary Spiegel, Rawad Abbas, Abdelaziz Amllay, Stavropoula I. Tjoumakaris, Michael R. Gooch, Nabeel A. Herial, Robert H. Rosenwasser, Hekmat Zarzour, Richard F. Schmidt, Vitor Mendes Pereira, Aman B. Patel, Pascal M. Jabbour and Adam A. Dmytriw
American Journal of Neuroradiology July 2024, 45 (7) 906-911; DOI: https://doi.org/10.3174/ajnr.A8324
Panagiotis Mastorakos
aFrom the Department of Neurosurgery (P.M., K.E.N., M.L., J. Castiglione, O.K., R.G., M.Z., R.A., A. Amllay, S.I.T., M.R.G., N.A.H., R.H.R., H.Z., R.F.S., P.M.J.), Thomas Jefferson University, Philadelphia, Pennsylvania
Kareem El Naamani
aFrom the Department of Neurosurgery (P.M., K.E.N., M.L., J. Castiglione, O.K., R.G., M.Z., R.A., A. Amllay, S.I.T., M.R.G., N.A.H., R.H.R., H.Z., R.F.S., P.M.J.), Thomas Jefferson University, Philadelphia, Pennsylvania
Nimer Adeeb
bDepartement of Neurosurgery and Neurointerventional Surgery (N.A., M.D., A. Aslan, H.H.C.-S.), Louisiana State University, Shreveport, Lousiana
Mathews Lan
aFrom the Department of Neurosurgery (P.M., K.E.N., M.L., J. Castiglione, O.K., R.G., M.Z., R.A., A. Amllay, S.I.T., M.R.G., N.A.H., R.H.R., H.Z., R.F.S., P.M.J.), Thomas Jefferson University, Philadelphia, Pennsylvania
James Castiglione
aFrom the Department of Neurosurgery (P.M., K.E.N., M.L., J. Castiglione, O.K., R.G., M.Z., R.A., A. Amllay, S.I.T., M.R.G., N.A.H., R.H.R., H.Z., R.F.S., P.M.J.), Thomas Jefferson University, Philadelphia, Pennsylvania
Omaditya Khanna
aFrom the Department of Neurosurgery (P.M., K.E.N., M.L., J. Castiglione, O.K., R.G., M.Z., R.A., A. Amllay, S.I.T., M.R.G., N.A.H., R.H.R., H.Z., R.F.S., P.M.J.), Thomas Jefferson University, Philadelphia, Pennsylvania
Ritam Ghosh
aFrom the Department of Neurosurgery (P.M., K.E.N., M.L., J. Castiglione, O.K., R.G., M.Z., R.A., A. Amllay, S.I.T., M.R.G., N.A.H., R.H.R., H.Z., R.F.S., P.M.J.), Thomas Jefferson University, Philadelphia, Pennsylvania
Jose Danilo Bengzon Diestro
cDivision of Diagnostic and Therapeutic Neuroradiology, Department of Radiology, St. Michael’s Hospital (J.D.B.D., N.M.C., J.S., V.M.P., A.A.D.), University of Toronto, Toronto, Ontario, Canada
Mahmoud Dibas
bDepartement of Neurosurgery and Neurointerventional Surgery (N.A., M.D., A. Aslan, H.H.C.-S.), Louisiana State University, Shreveport, Lousiana
Rachel M. McLellan
dNeuroendovascular Program (R.M.M., J.E.V., J.D.R., N.J.P., C.J.S., M.A.A.-S., A.B.P., A.A.D.), Massachusetts General Hospital and Brigham and Women’s Hospital, Harvard University, Boston, Massachusetts
Oktay Algin
eDepartment of Radiology (O.A., M.O.O., G.A.), City Hospital, Bilkent, Medical Faculty of Yıldırım Beyazıt University, Ankara, Turkey
Sherief Ghozy
fDepartments of Radiology and Neurosurgery (S.G.), Mayo Clinic, Rochester, Minnesota
Nicole M. Cancelliere
cDivision of Diagnostic and Therapeutic Neuroradiology, Department of Radiology, St. Michael’s Hospital (J.D.B.D., N.M.C., J.S., V.M.P., A.A.D.), University of Toronto, Toronto, Ontario, Canada
Assala Aslan
bDepartement of Neurosurgery and Neurointerventional Surgery (N.A., M.D., A. Aslan, H.H.C.-S.), Louisiana State University, Shreveport, Lousiana
Hugo H. Cuellar-Saenz
bDepartement of Neurosurgery and Neurointerventional Surgery (N.A., M.D., A. Aslan, H.H.C.-S.), Louisiana State University, Shreveport, Lousiana
Sovann V. Lay
gService de Neuroradiologie Diagnostique et Thérapeutique (S.V.L.), Centre Hospitalier de Toulouse, Hôpital Purpan, Toulouse, France
Adrien Guenego
hService de Neuroradiologie Interventionnelle (A.G., S.E., B.T.J., B.L.), Hôpital Universitaire Erasme, Bruxelles, Belgique
Leonardo Renieri
iInterventistica Neurovascolare (L.R., N.L.), Ospedale Careggi di Firenze, Florence, Italy
Joseph Carnevale
jNeurosurgery and Interventional Neuroradiology, Weill Cornell School of Medicine (J. Carnevale, R.W.R., S.B., J.K.), NY Presbyterian Hospital, New York, New York
Guillaume Saliou
kService de Radiodiagnostic et Radiologie Interventionnelle (G. Saliou), Centre Hospitalier Vaudois de Lausanne, Lausanne, Switzerland
Eimad Shotar
lDepartment de Neuroradiologie (E.S., K.P., F.C.), Hôpital Pitié-Salpêtrière, Université Sorbonne, Paris, France
Kevin Premat
lDepartment de Neuroradiologie (E.S., K.P., F.C.), Hôpital Pitié-Salpêtrière, Université Sorbonne, Paris, France
Markus Möhlenbruch
mSektion Vaskuläre und Interventionelle Neuroradiologie (M. Möhlenbruch, C.U.), Universitätsklinikum Heidelberg, Heidelberg, Germany
Michael Kral
nDepartment of Neurology/Institute of Neurointervention (M.K., M.K.-O., C.J.G.), Christian Doppler University Hospital and Institute of Neurointervention, Paracelsus Medical University, Salzburg, Austria
Justin E. Vranic
dNeuroendovascular Program (R.M.M., J.E.V., J.D.R., N.J.P., C.J.S., M.A.A.-S., A.B.P., A.A.D.), Massachusetts General Hospital and Brigham and Women’s Hospital, Harvard University, Boston, Massachusetts
Charlotte Chung
oDepartments of Radiology and Neurosurgery (C.C., E.N., E.R., H.A.), NYU Langone Health Center, New York, New York
Mohamed M. Salem
pDepartment of Neurosurgery (M.M.S., B.T. Jankowitz, J.-K.B.), University of Pennsylvania Medical Center, Philadelphia, Pennsylvania
Ivan Lylyk
qEquipo de Neurocirugía Endovascular y Radiología Intervencionista (I.L., P.L.), Clínica La Sagrada Familia, Buenos Aires, Argentina
Paul M. Foreman
rNeurosurgery Department (P.M.F., J.A.V.), Orlando Health Neuroscience and Rehabilitation Institute, Orlando, Florida
Jay A. Vachhani
rNeurosurgery Department (P.M.F., J.A.V.), Orlando Health Neuroscience and Rehabilitation Institute, Orlando, Florida
Hamza Shaikh
sDepartments of Radiology and Neurosurgery (H.S.), Cooper University Health Care, Cooper Medical School of Rowan University, Camden, New Jersey
Vedran Župančić
tSubdivision of Interventional Neuroradiology, Department of Radiology (V.Ž.), Clinical Hospital Center Sisters of Mercy, Zagreb, Croatia
Muhammad U. Hafeez
uDepartment of Neurosurgery (M.U.H., P.K., V.K.), UTMB and Baylor School of Medicine, Houston, Texas
Joshua Catapano
vDepartment of Neurosurgery (J. Catapano, A.F.D., F.C.A.), Barrow Neurological Institute, Phoenix, Arizona
Muhammad Waqas
wDepartment of Neurosurgery (M.W., V.M.T., A.S.), State University of New York at Buffalo, Buffalo, New York
Vincent M. Tutino
wDepartment of Neurosurgery (M.W., V.M.T., A.S.), State University of New York at Buffalo, Buffalo, New York
Mohamed K. Ibrahim
xDepartments of Radiology and Neurosurgery (M.K.I., M.A.M., W.B.), Mayo Clinic, Rochester, Minnesota
Marwa A. Mohammed
xDepartments of Radiology and Neurosurgery (M.K.I., M.A.M., W.B.), Mayo Clinic, Rochester, Minnesota
James D. Rabinov
dNeuroendovascular Program (R.M.M., J.E.V., J.D.R., N.J.P., C.J.S., M.A.A.-S., A.B.P., A.A.D.), Massachusetts General Hospital and Brigham and Women’s Hospital, Harvard University, Boston, Massachusetts
Yifan Ren
yInterventional Radiology and Neurointerventional Services, Department of Radiology (Y.R., R.G.T.), Austin Health, Melbourne, Victoria, Australia
Clemens M. Schirmer
zDepartment of Neurosurgery and Radiology (C.M.S.), Geisinger Hospital, Danville, Pennsylvania
Mariangela Piano
aaInterventistica Neurovascolare (M. Piano, P.P., G.P.), Ospedale Niguarda Cà Granda, Milano, Italy
Maria Bres Bullrich
bbNeurointerventional Program, Departments of Medical Imaging and Clinical Neurological Sciences (M.B.B., M. Mayich), London Health Sciences Centre, Western University, London, Ontario, Canada
Michael Mayich
bbNeurointerventional Program, Departments of Medical Imaging and Clinical Neurological Sciences (M.B.B., M. Mayich), London Health Sciences Centre, Western University, London, Ontario, Canada
Anna L. Kühn
ccDepartment of Neurointerventional Radiology (A.L.K., A.S.P.), UMass Memorial Hospital, Worcester, Massachusetts
Caterina Michelozzi
ddInterventistica Neurovascolare (C.M.), Ospedale San Raffaele Milano, Milano, Italy
Stéphanie Elens
hService de Neuroradiologie Interventionnelle (A.G., S.E., B.T.J., B.L.), Hôpital Universitaire Erasme, Bruxelles, Belgique
Robert M. Starke
eeDepartment of Neurosurgery (R.M.S.), University of Miami, Miami, Florida
Ameer E. Hassan
ffDeparment of Neuroscience (A.E.H.), Valley Baptist Neuroscience Institute, Harlingen, Texas
Mark Ogilvie
ggDepartments of Neurosurgery and Radiology (M.O., J.J.), University of Alabama at Birmingham, Birmingham, Alabama
Anh Nguyen
hhDepartment of Diagnostic and Interventional Neuroradiology (A.N., M. Psychogios), University Hospital Basel, Basel, Switzerland
Jesse Jones
ggDepartments of Neurosurgery and Radiology (M.O., J.J.), University of Alabama at Birmingham, Birmingham, Alabama
Waleed Brinjikji
xDepartments of Radiology and Neurosurgery (M.K.I., M.A.M., W.B.), Mayo Clinic, Rochester, Minnesota
Marios Psychogios
hhDepartment of Diagnostic and Interventional Neuroradiology (A.N., M. Psychogios), University Hospital Basel, Basel, Switzerland
Christian Ulfert
mSektion Vaskuläre und Interventionelle Neuroradiologie (M. Möhlenbruch, C.U.), Universitätsklinikum Heidelberg, Heidelberg, Germany
Julian Spears
cDivision of Diagnostic and Therapeutic Neuroradiology, Department of Radiology, St. Michael’s Hospital (J.D.B.D., N.M.C., J.S., V.M.P., A.A.D.), University of Toronto, Toronto, Ontario, Canada
Brian T. Jankowitz
pDepartment of Neurosurgery (M.M.S., B.T. Jankowitz, J.-K.B.), University of Pennsylvania Medical Center, Philadelphia, Pennsylvania
Jan-Karl Burkhardt
pDepartment of Neurosurgery (M.M.S., B.T. Jankowitz, J.-K.B.), University of Pennsylvania Medical Center, Philadelphia, Pennsylvania
Ricardo A. Domingo
iiDepartments of Radiology & Neurosurgery (R.A.D., T.H.), Mayo Clinic, Jacksonville, Florida
Thien Huynh
iiDepartments of Radiology & Neurosurgery (R.A.D., T.H.), Mayo Clinic, Jacksonville, Florida
Rabih G. Tawk
yInterventional Radiology and Neurointerventional Services, Department of Radiology (Y.R., R.G.T.), Austin Health, Melbourne, Victoria, Australia
Boris Lubicz
hService de Neuroradiologie Interventionnelle (A.G., S.E., B.T.J., B.L.), Hôpital Universitaire Erasme, Bruxelles, Belgique
Marie T. Nawka
jjDepartment of Diagnostic and Interventional Neuroradiology (M.T.N.), University Medical Center Hamburg-Eppendorf, Hamburg, Germany
Pietro Panni
aaInterventistica Neurovascolare (M. Piano, P.P., G.P.), Ospedale Niguarda Cà Granda, Milano, Italy
Ajit S. Puri
ccDepartment of Neurointerventional Radiology (A.L.K., A.S.P.), UMass Memorial Hospital, Worcester, Massachusetts
Guglielmo Pero
aaInterventistica Neurovascolare (M. Piano, P.P., G.P.), Ospedale Niguarda Cà Granda, Milano, Italy
Erez Nossek
oDepartments of Radiology and Neurosurgery (C.C., E.N., E.R., H.A.), NYU Langone Health Center, New York, New York
Eytan Raz
oDepartments of Radiology and Neurosurgery (C.C., E.N., E.R., H.A.), NYU Langone Health Center, New York, New York
Monika Killer-Oberpfalzer
nDepartment of Neurology/Institute of Neurointervention (M.K., M.K.-O., C.J.G.), Christian Doppler University Hospital and Institute of Neurointervention, Paracelsus Medical University, Salzburg, Austria
M. Ozgur Ozates
eDepartment of Radiology (O.A., M.O.O., G.A.), City Hospital, Bilkent, Medical Faculty of Yıldırım Beyazıt University, Ankara, Turkey
Giyas Ayberk
eDepartment of Radiology (O.A., M.O.O., G.A.), City Hospital, Bilkent, Medical Faculty of Yıldırım Beyazıt University, Ankara, Turkey
Robert W. Regenhardt
jNeurosurgery and Interventional Neuroradiology, Weill Cornell School of Medicine (J. Carnevale, R.W.R., S.B., J.K.), NY Presbyterian Hospital, New York, New York
Christoph J. Griessenauer
nDepartment of Neurology/Institute of Neurointervention (M.K., M.K.-O., C.J.G.), Christian Doppler University Hospital and Institute of Neurointervention, Paracelsus Medical University, Salzburg, Austria
Hamed Asadi
oDepartments of Radiology and Neurosurgery (C.C., E.N., E.R., H.A.), NYU Langone Health Center, New York, New York
Adnan Siddiqui
wDepartment of Neurosurgery (M.W., V.M.T., A.S.), State University of New York at Buffalo, Buffalo, New York
Andrew F. Ducruet
vDepartment of Neurosurgery (J. Catapano, A.F.D., F.C.A.), Barrow Neurological Institute, Phoenix, Arizona
Felipe C. Albuquerque
vDepartment of Neurosurgery (J. Catapano, A.F.D., F.C.A.), Barrow Neurological Institute, Phoenix, Arizona
Nirav J. Patel
dNeuroendovascular Program (R.M.M., J.E.V., J.D.R., N.J.P., C.J.S., M.A.A.-S., A.B.P., A.A.D.), Massachusetts General Hospital and Brigham and Women’s Hospital, Harvard University, Boston, Massachusetts
Christopher J. Stapleton
dNeuroendovascular Program (R.M.M., J.E.V., J.D.R., N.J.P., C.J.S., M.A.A.-S., A.B.P., A.A.D.), Massachusetts General Hospital and Brigham and Women’s Hospital, Harvard University, Boston, Massachusetts
Peter Kan
uDepartment of Neurosurgery (M.U.H., P.K., V.K.), UTMB and Baylor School of Medicine, Houston, Texas
Vladimir Kalousek
uDepartment of Neurosurgery (M.U.H., P.K., V.K.), UTMB and Baylor School of Medicine, Houston, Texas
Pedro Lylyk
qEquipo de Neurocirugía Endovascular y Radiología Intervencionista (I.L., P.L.), Clínica La Sagrada Familia, Buenos Aires, Argentina
Srikanth Boddu
jNeurosurgery and Interventional Neuroradiology, Weill Cornell School of Medicine (J. Carnevale, R.W.R., S.B., J.K.), NY Presbyterian Hospital, New York, New York
Jared Knopman
jNeurosurgery and Interventional Neuroradiology, Weill Cornell School of Medicine (J. Carnevale, R.W.R., S.B., J.K.), NY Presbyterian Hospital, New York, New York
Mohammad A. Aziz-Sultan
dNeuroendovascular Program (R.M.M., J.E.V., J.D.R., N.J.P., C.J.S., M.A.A.-S., A.B.P., A.A.D.), Massachusetts General Hospital and Brigham and Women’s Hospital, Harvard University, Boston, Massachusetts
Frédéric Clarençon
lDepartment de Neuroradiologie (E.S., K.P., F.C.), Hôpital Pitié-Salpêtrière, Université Sorbonne, Paris, France
Nicola Limbucci
iInterventistica Neurovascolare (L.R., N.L.), Ospedale Careggi di Firenze, Florence, Italy
Mario Zanaty
aFrom the Department of Neurosurgery (P.M., K.E.N., M.L., J. Castiglione, O.K., R.G., M.Z., R.A., A. Amllay, S.I.T., M.R.G., N.A.H., R.H.R., H.Z., R.F.S., P.M.J.), Thomas Jefferson University, Philadelphia, Pennsylvania
Juan Carlos Martinez-Gutierrez
kkDepartment of Neurology (J.C.M.-G., S.S., G. Spiegel), UTHealth McGovern Medical School, Houston, Texas
Sunil Sheth
kkDepartment of Neurology (J.C.M.-G., S.S., G. Spiegel), UTHealth McGovern Medical School, Houston, Texas
Gary Spiegel
kkDepartment of Neurology (J.C.M.-G., S.S., G. Spiegel), UTHealth McGovern Medical School, Houston, Texas
Rawad Abbas
aFrom the Department of Neurosurgery (P.M., K.E.N., M.L., J. Castiglione, O.K., R.G., M.Z., R.A., A. Amllay, S.I.T., M.R.G., N.A.H., R.H.R., H.Z., R.F.S., P.M.J.), Thomas Jefferson University, Philadelphia, Pennsylvania
Abdelaziz Amllay
aFrom the Department of Neurosurgery (P.M., K.E.N., M.L., J. Castiglione, O.K., R.G., M.Z., R.A., A. Amllay, S.I.T., M.R.G., N.A.H., R.H.R., H.Z., R.F.S., P.M.J.), Thomas Jefferson University, Philadelphia, Pennsylvania
Stavropoula I. Tjoumakaris
aFrom the Department of Neurosurgery (P.M., K.E.N., M.L., J. Castiglione, O.K., R.G., M.Z., R.A., A. Amllay, S.I.T., M.R.G., N.A.H., R.H.R., H.Z., R.F.S., P.M.J.), Thomas Jefferson University, Philadelphia, Pennsylvania
Michael R. Gooch
aFrom the Department of Neurosurgery (P.M., K.E.N., M.L., J. Castiglione, O.K., R.G., M.Z., R.A., A. Amllay, S.I.T., M.R.G., N.A.H., R.H.R., H.Z., R.F.S., P.M.J.), Thomas Jefferson University, Philadelphia, Pennsylvania
Nabeel A. Herial
aFrom the Department of Neurosurgery (P.M., K.E.N., M.L., J. Castiglione, O.K., R.G., M.Z., R.A., A. Amllay, S.I.T., M.R.G., N.A.H., R.H.R., H.Z., R.F.S., P.M.J.), Thomas Jefferson University, Philadelphia, Pennsylvania
Robert H. Rosenwasser
aFrom the Department of Neurosurgery (P.M., K.E.N., M.L., J. Castiglione, O.K., R.G., M.Z., R.A., A. Amllay, S.I.T., M.R.G., N.A.H., R.H.R., H.Z., R.F.S., P.M.J.), Thomas Jefferson University, Philadelphia, Pennsylvania
Hekmat Zarzour
aFrom the Department of Neurosurgery (P.M., K.E.N., M.L., J. Castiglione, O.K., R.G., M.Z., R.A., A. Amllay, S.I.T., M.R.G., N.A.H., R.H.R., H.Z., R.F.S., P.M.J.), Thomas Jefferson University, Philadelphia, Pennsylvania
Richard F. Schmidt
aFrom the Department of Neurosurgery (P.M., K.E.N., M.L., J. Castiglione, O.K., R.G., M.Z., R.A., A. Amllay, S.I.T., M.R.G., N.A.H., R.H.R., H.Z., R.F.S., P.M.J.), Thomas Jefferson University, Philadelphia, Pennsylvania
Vitor Mendes Pereira
cDivision of Diagnostic and Therapeutic Neuroradiology, Department of Radiology, St. Michael’s Hospital (J.D.B.D., N.M.C., J.S., V.M.P., A.A.D.), University of Toronto, Toronto, Ontario, Canada
Aman B. Patel
dNeuroendovascular Program (R.M.M., J.E.V., J.D.R., N.J.P., C.J.S., M.A.A.-S., A.B.P., A.A.D.), Massachusetts General Hospital and Brigham and Women’s Hospital, Harvard University, Boston, Massachusetts
Pascal M. Jabbour
aFrom the Department of Neurosurgery (P.M., K.E.N., M.L., J. Castiglione, O.K., R.G., M.Z., R.A., A. Amllay, S.I.T., M.R.G., N.A.H., R.H.R., H.Z., R.F.S., P.M.J.), Thomas Jefferson University, Philadelphia, Pennsylvania
Adam A. Dmytriw
cDivision of Diagnostic and Therapeutic Neuroradiology, Department of Radiology, St. Michael’s Hospital (J.D.B.D., N.M.C., J.S., V.M.P., A.A.D.), University of Toronto, Toronto, Ontario, Canada
dNeuroendovascular Program (R.M.M., J.E.V., J.D.R., N.J.P., C.J.S., M.A.A.-S., A.B.P., A.A.D.), Massachusetts General Hospital and Brigham and Women’s Hospital, Harvard University, Boston, Massachusetts
Article Figures & Data
Tables
No. (%), Mean (SD) Total No. of patients 763 Sex (female) 510 (66.8) Mean age (yr) 59.9 (SD, 11.7) Smoking statusa Current 210 (31.2) Former 193 (28.7) Nonsmoker 270 (40.1) Ruptured aneurysm 230 (30.1) Aneurysm location AcomA 223 (29.2) Basilar tip 123 (16.1) ACA 56 (7.3) ICA 15 (2.0) MCA 206 (27.0) PcomA 54 (7.1) PICA 14 (1.8) ICA terminus 60 (7.9) SCA 5 (0.7) VA 6 (0.8) PCA 1 (0.1) Mean aneurysm neck (mm)b 4.0 (SD, 1.4) Mean maximal diameter (mm) 6.9 (SD, 2.4) Mean aneurysm height (mm)c 6.1 (SD, 2.3) Mean aneurysm width (mm)d 5.8 (SD, 2.1) Bifurcation aneurysms 639 (83.7) Daughter sace 215 (30.1) Vessel from aneurysm wallf 78 (10.4) Preprocedural AP/ACg None 327 (46.6) Single agent 91 (12.1) Two agents 283 (40.4) ↵Data missing for a = 90, b = 66, c = 10, d = 4, e = 351, f = 49, g = 10, h = 62.
Note:—AcomA indicates anterior communicating artery; PcomA, posterior communicating artery; ACA, anterior cerebral artery; SCA, superior cerebellar artery; VA, vertebral artery; PCA, posterior cerebral artery; AP/AC, antiplatelets/anticoagulants.
- Table 2:
Occlusion rates of treated aneurysms intraoperatively and at most recent follow-up
No. (%), Mean (SD) Mean duration of procedure (min)a 88.0 (47.9) Immediate occlusionb 100% 212 (29.2) >90% 185 (25.5) <90% 328 (45.2) Contrast stasis in nonoccluded aneurysmsc 485 (90.3) Mean duration to last follow-up (mo) 17.7 (20.3) Technique of last follow-upd DSA 206 (27.3) MRA 376 (49.9) CTA 131 (17.4) MRA/DSA 9 (1.2) CTA/DSA 5 (0.7) MRA/CTA 27 (3.6) Occlusion at last follow-upe Complete 497 (71.5) Near-complete occlusion 139 (20) Aneurysm residual 59 (8.5) Complete occlusion 497 (65.1) Retreatment 56 (7.3) Note:—Data missing for a = 113, b = 37, c = 68, d = 9, e = 68.
- Table 3:
Intraoperative degree of occlusion and stasis as predictors of long-term outcomes
Imaging Findings Management Obliteration Residual/Recurrence P Value Treatment No. Treatment P Value Intraoperative 100% occlusion 175 (85%)a 31 (15%)a <.001a 4 (1.9%)a 207 (98.1%)a <.001a 90%–99% occlusion 94 (51.4%) 89 (48.6%) 18 (9.7%) 167 (90.3%) <90% occlusion 200 (61.3%) 126 (38.7%) 34 (10.4%) 193 (89.6%) Contrast stasis 284 (59.2%) 196 (40.8%) .259 48 (9.9%) 436 (90.1%) .606 No stasis 26 (51%) 25 (49%) 4 (7.7%) 48 (92.3%) a Significant.
- Table 4:
Test parameters of intraoperative complete occlusion as a predictor of long-term obliteration and no additional treatment
Obliteration at Last Follow-Up P Value No Retreatment P Value Sensitivity .373 Sensitivity .310 Specificity .874 Specificity .929 Positive predictive value .850 Positive predictive value .981 Negative predictive value .422 Negative predictive value .102 Positive likelihood ratio 2.961 Positive likelihood ratio 4.345 Pearson χ2 P value <.001a Pearson χ2 P value <.001a ROC curve P value <.001a ROC curve P value .003a ↵a Significant.
In this issue
American Journal of Neuroradiology
Vol. 45, Issue 7
1 Jul 2024
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Panagiotis Mastorakos, Kareem El Naamani, Nimer Adeeb, Mathews Lan, James Castiglione, Omaditya Khanna, Ritam Ghosh, Jose Danilo Bengzon Diestro, Mahmoud Dibas, Rachel M. McLellan, Oktay Algin, Sherief Ghozy, Nicole M. Cancelliere, Assala Aslan, Hugo H. Cuellar-Saenz, Sovann V. Lay, Adrien Guenego, Leonardo Renieri, Joseph Carnevale, Guillaume Saliou, Eimad Shotar, Kevin Premat, Markus Möhlenbruch, Michael Kral, Justin E. Vranic, Charlotte Chung, Mohamed M. Salem, Ivan Lylyk, Paul M. Foreman, Jay A. Vachhani, Hamza Shaikh, Vedran Župančić, Muhammad U. Hafeez, Joshua Catapano, Muhammad Waqas, Vincent M. Tutino, Mohamed K. Ibrahim, Marwa A. Mohammed, James D. Rabinov, Yifan Ren, Clemens M. Schirmer, Mariangela Piano, Maria Bres Bullrich, Michael Mayich, Anna L. Kühn, Caterina Michelozzi, Stéphanie Elens, Robert M. Starke, Ameer E. Hassan, Mark Ogilvie, Anh Nguyen, Jesse Jones, Waleed Brinjikji, Marios Psychogios, Christian Ulfert, Julian Spears, Brian T. Jankowitz, Jan-Karl Burkhardt, Ricardo A. Domingo, Thien Huynh, Rabih G. Tawk, Boris Lubicz, Marie T. Nawka, Pietro Panni, Ajit S. Puri, Guglielmo Pero, Erez Nossek, Eytan Raz, Monika Killer-Oberpfalzer, M. Ozgur Ozates, Giyas Ayberk, Robert W. Regenhardt, Christoph J. Griessenauer, Hamed Asadi, Adnan Siddiqui, Andrew F. Ducruet, Felipe C. Albuquerque, Nirav J. Patel, Christopher J. Stapleton, Peter Kan, Vladimir Kalousek, Pedro Lylyk, Srikanth Boddu, Jared Knopman, Mohammad A. Aziz-Sultan, Frédéric Clarençon, Nicola Limbucci, Mario Zanaty, Juan Carlos Martinez-Gutierrez, Sunil Sheth, Gary Spiegel, Rawad Abbas, Abdelaziz Amllay, Stavropoula I. Tjoumakaris, Michael R. Gooch, Nabeel A. Herial, Robert H. Rosenwasser, Hekmat Zarzour, Richard F. Schmidt, Vitor Mendes Pereira, Aman B. Patel, Pascal M. Jabbour, Adam A. Dmytriw
Predictors of Aneurysm Obliteration in Patients Treated with the WEB Device: Results of a Multicenter Retrospective Study
American Journal of Neuroradiology Jul 2024, 45 (7) 906-911; DOI: 10.3174/ajnr.A8324
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Predicting Aneurysm Obliteration with WEB Device
Panagiotis Mastorakos, Kareem El Naamani, Nimer Adeeb, Mathews Lan, James Castiglione, Omaditya Khanna, Ritam Ghosh, Jose Danilo Bengzon Diestro, Mahmoud Dibas, Rachel M. McLellan, Oktay Algin, Sherief Ghozy, Nicole M. Cancelliere, Assala Aslan, Hugo H. Cuellar-Saenz, Sovann V. Lay, Adrien Guenego, Leonardo Renieri, Joseph Carnevale, Guillaume Saliou, Eimad Shotar, Kevin Premat, Markus Möhlenbruch, Michael Kral, Justin E. Vranic, Charlotte Chung, Mohamed M. Salem, Ivan Lylyk, Paul M. Foreman, Jay A. Vachhani, Hamza Shaikh, Vedran Župančić, Muhammad U. Hafeez, Joshua Catapano, Muhammad Waqas, Vincent M. Tutino, Mohamed K. Ibrahim, Marwa A. Mohammed, James D. Rabinov, Yifan Ren, Clemens M. Schirmer, Mariangela Piano, Maria Bres Bullrich, Michael Mayich, Anna L. Kühn, Caterina Michelozzi, Stéphanie Elens, Robert M. Starke, Ameer E. Hassan, Mark Ogilvie, Anh Nguyen, Jesse Jones, Waleed Brinjikji, Marios Psychogios, Christian Ulfert, Julian Spears, Brian T. Jankowitz, Jan-Karl Burkhardt, Ricardo A. Domingo, Thien Huynh, Rabih G. Tawk, Boris Lubicz, Marie T. Nawka, Pietro Panni, Ajit S. Puri, Guglielmo Pero, Erez Nossek, Eytan Raz, Monika Killer-Oberpfalzer, M. Ozgur Ozates, Giyas Ayberk, Robert W. Regenhardt, Christoph J. Griessenauer, Hamed Asadi, Adnan Siddiqui, Andrew F. Ducruet, Felipe C. Albuquerque, Nirav J. Patel, Christopher J. Stapleton, Peter Kan, Vladimir Kalousek, Pedro Lylyk, Srikanth Boddu, Jared Knopman, Mohammad A. Aziz-Sultan, Frédéric Clarençon, Nicola Limbucci, Mario Zanaty, Juan Carlos Martinez-Gutierrez, Sunil Sheth, Gary Spiegel, Rawad Abbas, Abdelaziz Amllay, Stavropoula I. Tjoumakaris, Michael R. Gooch, Nabeel A. Herial, Robert H. Rosenwasser, Hekmat Zarzour, Richard F. Schmidt, Vitor Mendes Pereira, Aman B. Patel, Pascal M. Jabbour, Adam A. Dmytriw
American Journal of Neuroradiology Jul 2024, 45 (7) 906-911; DOI: 10.3174/ajnr.A8324
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