More articles from Adult Brain
- Atypical Presentations of Intracranial Hypotension: Comparison with Classic Spontaneous Intracranial Hypotension
The authors evaluated the clinical records and neuroimaging of patients with spontaneous intracranial hypotension from September 2005 to August 2014. Patients with classic spontaneous intracranial hypotension (n = 33) were compared with those with intracranial hypotension with atypical clinical presentation (n = 8). There was no significant difference in dural enhancement, subdural hematomas, or cerebellar tonsil herniation. Patients with atypical spontaneous intracranial hypotension had significantly more elongated anteroposterior midbrain diameter compared with those with classic spontaneous intracranial hypotension, and shortened pontomammillary distance. In this population, patients with atypical spontaneous intracranial hypotension showed a more chronic syndrome compared with classic spontaneous intracranial hypotension, more severe brain sagging, lower rates of clinical response, and frequent relapses.
- Mapping the Orientation of White Matter Fiber Bundles: A Comparative Study of Diffusion Tensor Imaging, Diffusional Kurtosis Imaging, and Diffusion Spectrum Imaging
The authors evaluated fiber bundle orientations from DTI and diffusional kurtosis compared with diffusion spectrum imaging as a criterion standard to assess the performance of each technique. DTI, diffusional kurtosis imaging, and diffusion spectrum imaging datasets were acquired during 2 independent sessions in 3 volunteers. While orientation estimates from all 3 techniques had comparable angular reproducibility, diffusional kurtosis imaging decreased angular error throughout the white matter compared with DTI. Diffusion spectrum imaging and diffusional kurtosis imaging enabled the detection of crossing-fiber bundles. They conclude that fiber bundle orientation estimates from diffusional kurtosis imaging have less systematic error than those from DTI.