Case of the Week
Section Editors: Matylda Machnowska1 and Anvita Pauranik2
1University of Toronto, Toronto, Ontario, Canada
2BC Children's Hospital, University of British Columbia, Vancouver, British Columbia, Canada
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June 6, 2011
Neurosarcoidosis
- Sarcoidosis is an idiopathic systemic disease characterized by non-caseating granulomas.
- Neurologic involvement is uncommon, seen in approximately 5% of the cases.
- Clinical presentation is non-specific. It depends on the region of the brain involved. Headache, seizures, vision loss, facial nerve paresis, and signs and symptoms of meningeal irritation are common.
- Key Diagnostic Features: Leptomeningeal enhancement is typical. Cyst formation as seen in this case is uncommon. However, when seen, such cysts occur adjacent to the choroid plexus. Adjacent leptomeningeal enhancement is often seen, though it was not seen in current case. Secondary hydrocephalus is common.
- DDx: Racemose neurocysticercosis, Pilocytic astrocytoma, Neuroglial cyst
- Treatment: Immunosuppression, Corticosteroids
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