Article Figures & Data
Figures
- Fig 1.
Influence of baseline CT ASPECTS on outcome (90-day mRS), indicating better outcomes with higher ASPECTS and better outcome with endovascular therapy irrespective of ASPECTS.
- Fig 2.
Influence of the site of occlusion on outcome (90-day mRS), indicating better outcome with endovascular therapy irrespective of site and the greatest treatment effect in proximal M1 occlusions.
- Fig 3.
Outcomes (90-day mRS) in patients with a clot length of ≥8 mm, indicating statistically superior outcomes with endovascular therapy in these clots.
- Fig 4.
Influence of baseline collateral status on outcome (90-day mRS), indicating better outcomes with better collaterals, better outcomes with endovascular therapy irrespective of collateral quality, and the greatest treatment effect associated with excellent collaterals.
- Fig 5.
Mean mRS in dichotomized subgroups identified by classification and regression tree analysis indicating time to recanalization, initial ASPECTS, and TICI scores posttreatment as substantial predictors of outcome with the displayed cut-points for dichotomization.
Tables
- Table 1:
Univariate predictors of functional independence (mRS 0–2) at 90 days, endovascular arm onlya
Predictor No. Total No. Category Odds Ratio Lower CI Upper CI P Value ASPECTS (per unit) 95 NA 1.53 1.09 2.15 .015 ASPECTS 8–10 (vs 6–7) 95 71/24 2.74 1.06 7.08 .037 ASPECTS 9–10 (vs 6–8) 95 52/43 3.43 1.45 8.09 .005 M1 occlusion (vs non-M1) 95 60/35 2.12 0.90 4.97 .085 Onset-to-groin puncture (per 60 min) 94 NA 0.68 0.48 0.98 .040 TICI 3 postprocedure (vs ≤TICI 2b) 80 56/24 2.11 0.79 5.61 .13 TICI 2b/3 postprocedure (vs ≤TICI 2a) 80 70/10 1.80 0.47 6.82 .39 Collateral grade (per unit) 56 NA 2.77 1.13 6.82 .026 Clot length (per mm) 50 NA 1.12 0.96 1.30 .14 Clot length of ≥8 mm (vs <8 mm) 50 44/6 2.38 0.42 13.40 .32 Clot length of ≥13 mm (vs <13 mm) 50 23/27 2.48 0.71 8.66 .16 Note:—No. reflects the number of data points available for each variable; NA, not applicable.
↵a Univariate logistic regression analysis of patients undergoing endovascular therapy was performed with the following variables: ASPECTS (as scored on preprocedural head CT, 6–7 vs 8–10 and 6–8 vs 9–10), site of occlusion (M1 versus non-M1), onset to groin puncture, quality of recanalization (TICI scale), collateral grade, and clot length (>8 mm versus <8 mm).
- Table 2:
Multivariate predictors of functional independence (mRS 0–2) at 90 days, endovascular arm onlya
Predictor No. Total No. Category Odds Ratio Lower CI Upper CI P Value ASPECTS 9–10 (vs 6–8) 48 28/20 4.25 1.06 17.10 .042 Onset-to-groin puncture (per 60 min) 48 NA 0.79 0.44 1.42 .43 TICI 2b/3 postprocedure (vs ≤TICI 2a) 48 43/5 1.03 0.12 8.46 .98 Collateral grade (per unit) 48 NA 2.85 0.90 9.08 .076 Note:—No. reflects the number of data points available for each variable; NA, not applicable.
↵a Multivariate logistic regression analysis of patients undergoing endovascular therapy was performed with the following variables: ASPECTS (as scored on preprocedural head CT), onset to groin puncture, quality of recanalization (TICI scale), and collaterals.
