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Research ArticleNeurointervention

Transdural Blood Supply in Cerebral Arteriovenous Malformations: A Systematic Evaluation of Angioarchitecture

K.-P. Stein, C. Moenninghoff, A. Kneist, I.E. Sandalcioglu, M. Forsting and U. Sure
American Journal of Neuroradiology November 2018, DOI: https://doi.org/10.3174/ajnr.A5881
K.-P. Stein
aFrom the Departments of Neurosurgery (K.-P.S., A.K., U.S.)
cDepartment of Neurosurgery (K.-P.S., I.E.S.), Klinikum Region Hannover Hospital Nordstadt, Hannover, Germany.
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C. Moenninghoff
bDiagnostic and Interventional Radiology and Neuroradiology (C.M., M.F.), University Hospital Essen, University Duisburg-Essen, Essen, Germany
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A. Kneist
aFrom the Departments of Neurosurgery (K.-P.S., A.K., U.S.)
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I.E. Sandalcioglu
cDepartment of Neurosurgery (K.-P.S., I.E.S.), Klinikum Region Hannover Hospital Nordstadt, Hannover, Germany.
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M. Forsting
bDiagnostic and Interventional Radiology and Neuroradiology (C.M., M.F.), University Hospital Essen, University Duisburg-Essen, Essen, Germany
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U. Sure
aFrom the Departments of Neurosurgery (K.-P.S., A.K., U.S.)
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  • Fig 1.
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    Fig 1.

    Representative angiograms of the 3 applied TDBS grades (left side ICA, right side ECA). A and B, TDBS I with weak and marginal contrast of the nidus (arrowheads) by a single meningeal feeder (arrow). C and D, TDBS II with distinct and partial ECA supply. E and F, TDBS III with a strong and substantial nidal filling from the ECA branches.

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    Fig 2.

    Clinical symptoms in 32 patients with TDBS according to the suggested grading.

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    Fig 3.

    Clinical symptoms of 32 patients in relation to ICA/ECA flow patterns (low [l] versus high [h]).

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    Fig 4.

    Flow patterns in 32 patients in correlation with the applied TDBS grading.

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    Fig 5.

    Representative angiograms of the 3 identified vascular phenotypes of TDBS (left side ICA, right side ECA). A and B, Temple type. C and D, Occipital type. E and F, Transbasal type.

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    Fig 6.

    Clinical symptoms in 32 patients with TDBS, according to the 3 ECA phenotypes.

Tables

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    Table 1:

    Suggested grading of TDBS, depending on the proportion and intensity of nidus perfusion

    TDBS Grade
    IIIIII
    Proportion of nidus perfusionMarginal (<5%)Partial (5%–50%)Substantial (>50%)
    Intensity of nidus perfusionWeakDistinctStrong
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    Table 2:

    Clinical presentation of 507 patients with cerebral AVMs

    TDBS (No.) (%)No TDBS (No.) (%)Multinomial Logistic Regression
    P ValueOdds Ratio
    All patients (n = 535)39496
    Previous AVM treatment7 (18)21 (4)
    Enrolled patients (n = 507)32475
        Male10 (31)260 (55).0043.433
        Hemorrhage9 (28)225 (47).30.968
        Seizures8 (25)79 (17).41.672
        Headache7 (22)44 (9).063.024
        Other8 (25)127 (27)
    Age (U test) (yr)
        Mean46 ± 1440 ± 18.07
        Range13–752–87
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    Table 3:

    Angiographic characteristics in 507 patients with cerebral AVMs

    TDBS (No.) (%)No TDBS (No.) (%)Multinomial Logistic Regression
    P ValueOdds Ratio
    All patients32475
    Location
        Supratentorial27 (84)399 (84)
        Infratentorial5 (16)76 (16)
    Size
        <30 mm7 (22)253 (53)<.0001117.703
        >30–60 mm17 (53)199 (42)
        >60 mm8 (25)23 (5).00116.852
    Eloquence24 (75)252 (53).084.001
    Venous drainage
        Deep12 (38)175 (37).22.268
    Spetzler-Ponce class
        A9 (28)250 (53).040.042
        B13 (41)137 (29)
        C10 (31)88 (18).030.099
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Cite this article
K.-P. Stein, C. Moenninghoff, A. Kneist, I.E. Sandalcioglu, M. Forsting, U. Sure
Transdural Blood Supply in Cerebral Arteriovenous Malformations: A Systematic Evaluation of Angioarchitecture
American Journal of Neuroradiology Nov 2018, DOI: 10.3174/ajnr.A5881

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Transdural Blood Supply in Cerebral Arteriovenous Malformations: A Systematic Evaluation of Angioarchitecture
K.-P. Stein, C. Moenninghoff, A. Kneist, I.E. Sandalcioglu, M. Forsting, U. Sure
American Journal of Neuroradiology Nov 2018, DOI: 10.3174/ajnr.A5881
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