Article Figures & Data
Figures
- Fig 1.
Evaluation of recanalization with MRA and TOF-MRA. A, At postprocedural day 1, we routinely evaluate the status of occlusion using MR angiography. The dotted line shows a cross-section of B and C. B, A residual neck is observed in the right internal carotid artery aneurysm after coil embolization at postprocedural day 1. Dotted circles show a coil mass. C, Blood flow signal of the residual neck has increased (asterisk) at 1 year after endovascular embolization compared with postprocedural day 1. This increased blood flow signal is regarded as recanalization.
- Fig 2.
Comparison of the maximum size of aneurysms between the follow-up and non-follow-up groups. A total of 116 unruptured aneurysms were followed up for >5 years. These aneurysms were categorized as the follow-up-group. Thirty unruptured aneurysms could not be followed up for >5 years. These aneurysms were categorized as the non-follow-up group. The distribution of the maximum size of aneurysms between the follow-up and non-follow-up groups was not significantly different (P = .24, Student t test).
- Fig 3.
Kaplan-Meier analysis of the nonrecanalization rate. The nonrecanalization rate of embolized aneurysms was decreased by 2 years, and there was no recanalization after this time.
- Fig 4.
Correlation between recanalization and the size of aneurysms. The maximum size of aneurysms was significantly correlated with the recanalization rate (P = .019, Student t test).
- Fig 5.
The relationship between the size of aneurysms and the nonrecanalization rate using the Kaplan-Meier method. Aneurysms were divided into <5-mm, 5- to 10-mm, and >10-mm groups. Using the Kaplan-Meier method, we analyzed the relationship between time (months) and the nonrecanalization rate of treated aneurysms in each group. The thick line indicates the nonrecanalization rate of the <5-mm group. The dotted line indicates the 5- to 10-mm group. The dashed line indicates the >10-mm group. The Bonferroni method showed that the >10-mm group had a significantly higher recanalization rate within 2 years compared with the <5-mm group. Despite the size of the aneurysms, aneurysms in which recanalization was not observed within 2 years after the procedure were not recanalized after this time. Double asterisks indicate P = .021.
Tables
- Table 1:
Analysis of recanalization after endovascular embolization of unruptured aneurysms
Parameters Recanalization (n = 19) Nonrecanalization (n = 97) Total or Mean Value P Value Age (mean) (yr) 57.9 ± 12.1 59.6 ± 11.4 59.8 ± 11.3 .55a Sex (male/female) 3:16 31:66 34:82 .18b Location of the aneurysm (No.) .72b MCA 1 10 11 PcomA 1 7 8 ICA 12 50 62 BA tip 3 6 9 Others 2 24 26 Size of the aneurysm (No.) (mm) 9 6.8 7.1 .019a Balloon-assisted (No.) 17 69 86 .15b Stent-assisted (No.) 0 8 8 .34b CO/RN/RA (No.) 9/7/3 53/38/6 62/45/9 .34b (53%/38%/7.7%) Variable OR 95% CI P Value Age 0.99 0.95–1.04 .97 Sex 1.35 0.29–6.12 .69 Anterior/posterior 3.19 0.46–22.23 .22 Bifurcation type/nonbifurcation type 1.08 0.25–4.56 .91 Aneurysm location (ICA) 1.94 0.24–15.42 .52 Size (mm) 1.24 1.05–1.43 .006 No. of aneurysms 1.33 0.80–2.21 .27 Balloon-assisted 4.04 0.71–22.97 .084 Stent-assisted 0 0 .07 CO/RN/RA 1.05 0.38–2.86 .91 Follow-up period 1 0.99–1.00 .34
